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100637-60-3,MFCD00665896
Catalog No.:AA0002GQ

100637-60-3 | 4-(Carboxymethyl)-2h-1,4-benzothiazin-3(4h)-one

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1g
96%
in stock  
$145.00   $102.00
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5g
96%
in stock  
$544.00   $381.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0002GQ
Chemical Name:
4-(Carboxymethyl)-2h-1,4-benzothiazin-3(4h)-one
CAS Number:
100637-60-3
Molecular Formula:
C10H9NO3S
Molecular Weight:
223.2484
MDL Number:
MFCD00665896
SMILES:
OC(=O)CN1C(=O)CSc2c1cccc2
Properties
Computed Properties
 
Complexity:
282  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.2  

Downstream Synthesis Route

[1]Fujita;Ota;Ito;Yamamoto;Kawashima[Synthesis,1988,#8,p.599-604]

[1]Locationinpatent:experimentalpartGowda;Khader;Kalluraya;Shree,Padma;Shabaraya[EuropeanJournalofMedicinalChemistry,2011,vol.46,#9,p.4100-4106]

[2]Trapani;Latrofa;Franco;Liso[IlFarmaco,1995,vol.50,#2,p.107-112]

[3]CurrentPatentAssignee:TAISHOPHARMACEUTICALHOLDINGSCO.,LTD.-US4755509,1988,A

100637-60-3    17356-08-0   
2-amino-4N-aceticacidthiazolo2,3-b1,4benzothiazine 

[1]Nagarapu,Lingaiah;Ravirala,Narender[HeterocyclicCommunications,2001,vol.7,#5,p.433-438]

[1]Nagarapu,Lingaiah;Ravirala,Narender[HeterocyclicCommunications,2001,vol.7,#5,p.433-438]

100637-60-3   
2-carboxy-9N-aceticacidthiene3,2-b1,4benzothiazine 

[1]Nagarapu,Lingaiah;Ravirala,Narender[HeterocyclicCommunications,2001,vol.7,#5,p.433-438]

Literature

Title: Synthesis, characterization and pharmacological activity of 4-{[1-substituted aminomethyl-4-arylideneamino-5-sulfanyl-4,5-dihydro-1H-1,2,4-triazol-3-yl]methyl}-2H-1,4-benzothiazin-3(4H)-ones.

Journal: European journal of medicinal chemistry 20110901

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: 2-(3-Oxo-3,4-dihydro-2H-1,4-benzothia-zin-4-yl)acetohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20100901

Title: 4-(1H-Benzimidazol-2-ylmeth-yl)-2H-1,4-benzothia-zin-3(4H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

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SDS
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Tags:100637-60-3 Molecular Formula|100637-60-3 MDL|100637-60-3 SMILES|100637-60-3 4-(Carboxymethyl)-2h-1,4-benzothiazin-3(4h)-one