Home Fluorides 1017779-71-3
1017779-71-3,MFCD09832387
Catalog No.:AA0005EH

1017779-71-3 | 4,5-Difluoro-2-methoxyaniline

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$42.00   $29.00
- +
1g
98%
in stock  
$56.00   $39.00
- +
10g
95%
in stock  
$512.00   $359.00
- +
25g
95%
in stock  
$1,208.00   $846.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0005EH
Chemical Name:
4,5-Difluoro-2-methoxyaniline
CAS Number:
1017779-71-3
Molecular Formula:
C7H7F2NO
Molecular Weight:
159.1334
MDL Number:
MFCD09832387
SMILES:
COc1cc(F)c(cc1N)F
Properties
Computed Properties
 
Complexity:
134  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
1.4  

Downstream Synthesis Route

[1]Estrada,AnthonyA.;Liu,Xingrong;Baker-Glenn,Charles;Beresford,Alan;Burdick,DanielJ.;Chambers,Mark;Chan,BryanK.;Chen,Huifen;Ding,Xiao;Dipasquale,AntonioG.;Dominguez,SaraL.;Dotson,Jennafer;Drummond,Jason;Flagella,Michael;Flynn,Sean;Fuji,Reina;Gill,Andrew;Gunzner-Toste,Janet;Harris,SethF.;Heffron,TimothyP.;Kleinheinz,Tracy;Lee,DonnaW.;LePichon,ClaireE.;Lyssikatos,JosephP.;Medhurst,AndrewD.;Moffat,JohnG.;Mukund,Susmith;Nash,Kevin;Scearce-Levie,Kimberly;Sheng,Zejuan;Shore,DanielG.;Tran,Thuy;Trivedi,Naimisha;Wang,Shumei;Zhang,Shuo;Zhang,Xiaolin;Zhao,Guiling;Zhu,Haitao;Sweeney,ZacharyK.[JournalofMedicinalChemistry,2012,vol.55,#22,p.9416-9433]

[1]Estrada,AnthonyA.;Liu,Xingrong;Baker-Glenn,Charles;Beresford,Alan;Burdick,DanielJ.;Chambers,Mark;Chan,BryanK.;Chen,Huifen;Ding,Xiao;Dipasquale,AntonioG.;Dominguez,SaraL.;Dotson,Jennafer;Drummond,Jason;Flagella,Michael;Flynn,Sean;Fuji,Reina;Gill,Andrew;Gunzner-Toste,Janet;Harris,SethF.;Heffron,TimothyP.;Kleinheinz,Tracy;Lee,DonnaW.;LePichon,ClaireE.;Lyssikatos,JosephP.;Medhurst,AndrewD.;Moffat,JohnG.;Mukund,Susmith;Nash,Kevin;Scearce-Levie,Kimberly;Sheng,Zejuan;Shore,DanielG.;Tran,Thuy;Trivedi,Naimisha;Wang,Shumei;Zhang,Shuo;Zhang,Xiaolin;Zhao,Guiling;Zhu,Haitao;Sweeney,ZacharyK.[JournalofMedicinalChemistry,2012,vol.55,#22,p.9416-9433]

[1]Estrada,AnthonyA.;Liu,Xingrong;Baker-Glenn,Charles;Beresford,Alan;Burdick,DanielJ.;Chambers,Mark;Chan,BryanK.;Chen,Huifen;Ding,Xiao;Dipasquale,AntonioG.;Dominguez,SaraL.;Dotson,Jennafer;Drummond,Jason;Flagella,Michael;Flynn,Sean;Fuji,Reina;Gill,Andrew;Gunzner-Toste,Janet;Harris,SethF.;Heffron,TimothyP.;Kleinheinz,Tracy;Lee,DonnaW.;LePichon,ClaireE.;Lyssikatos,JosephP.;Medhurst,AndrewD.;Moffat,JohnG.;Mukund,Susmith;Nash,Kevin;Scearce-Levie,Kimberly;Sheng,Zejuan;Shore,DanielG.;Tran,Thuy;Trivedi,Naimisha;Wang,Shumei;Zhang,Shuo;Zhang,Xiaolin;Zhao,Guiling;Zhu,Haitao;Sweeney,ZacharyK.[JournalofMedicinalChemistry,2012,vol.55,#22,p.9416-9433]

[1]Estrada,AnthonyA.;Liu,Xingrong;Baker-Glenn,Charles;Beresford,Alan;Burdick,DanielJ.;Chambers,Mark;Chan,BryanK.;Chen,Huifen;Ding,Xiao;Dipasquale,AntonioG.;Dominguez,SaraL.;Dotson,Jennafer;Drummond,Jason;Flagella,Michael;Flynn,Sean;Fuji,Reina;Gill,Andrew;Gunzner-Toste,Janet;Harris,SethF.;Heffron,TimothyP.;Kleinheinz,Tracy;Lee,DonnaW.;LePichon,ClaireE.;Lyssikatos,JosephP.;Medhurst,AndrewD.;Moffat,JohnG.;Mukund,Susmith;Nash,Kevin;Scearce-Levie,Kimberly;Sheng,Zejuan;Shore,DanielG.;Tran,Thuy;Trivedi,Naimisha;Wang,Shumei;Zhang,Shuo;Zhang,Xiaolin;Zhao,Guiling;Zhu,Haitao;Sweeney,ZacharyK.[JournalofMedicinalChemistry,2012,vol.55,#22,p.9416-9433]

1017779-71-3   
2-bromo-3,4-difluoro-6-methoxyaniline 

[1]CurrentPatentAssignee:JOHNSON&JOHNSONINC-US2022/89538,2022,A1Locationinpatent:Paragraph0277;0434;0435

[2]CurrentPatentAssignee:GruenenthalPharmaGmbH&Co.Kommanditgesellschaft-US2020/24281,2020,A1Locationinpatent:Paragraph0440;0445-0446

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Tags:1017779-71-3 Molecular Formula|1017779-71-3 MDL|1017779-71-3 SMILES|1017779-71-3 4,5-Difluoro-2-methoxyaniline |Fluorinated_Building_Blocks