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102146-07-6,MFCD00055117
Catalog No.:AA0006NN

102146-07-6 | 1H-Purine-2,6-dione, 8-cyclopentyl-3,9-dihydro-1,3-dipropyl-

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10mg
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25mg
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50mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0006NN
Chemical Name:
1H-Purine-2,6-dione, 8-cyclopentyl-3,9-dihydro-1,3-dipropyl-
CAS Number:
102146-07-6
Molecular Formula:
C16H24N4O2
Molecular Weight:
304.3874
MDL Number:
MFCD00055117
SMILES:
CCCn1c2[nH]c(nc2c(=O)n(c1=O)CCC)C1CCCC1
Properties
Properties
 
BP:
535.1°C at760mmHg  
Form:
Solid  
MP:
178 °C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
436  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
4  

Literature

Title: Alpha-naphthylisothiocyanate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes.

Journal: Toxicology 20160831

Title: A Positive Allosteric Modulator of the Adenosine A1 Receptor Selectively Inhibits Primary Afferent Synaptic Transmission in a Neuropathic Pain Model.

Journal: Molecular pharmacology 20150901

Title: Endogenous A1 adenosine receptor protects mice from acute ethanol-induced hepatotoxicity.

Journal: Toxicology 20130705

Title: Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.

Journal: European journal of medicinal chemistry 20130501

Title: Loss of A(1) adenosine receptor attenuates alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130101

Title: Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia.

Journal: PloS one 20130101

Title: Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slices.

Journal: Neuroscience 20121025

Title: A₁ adenosine receptor modulation of chemically and electrically evoked lumbar locomotor network activity in isolated newborn rat spinal cords.

Journal: Neuroscience 20121011

Title: Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20121003

Title: Genetic inactivation of the adenosine A(2A) receptor exacerbates brain damage in mice with experimental autoimmune encephalomyelitis.

Journal: Journal of neurochemistry 20121001

Title: A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A(1) receptors and enhances consolidation of step-down avoidance.

Journal: Behavioural brain research 20121001

Title: Expression of A1 adenosine receptors in the developing avian retina: in vivo modulation by A(2A) receptors and endogenous adenosine.

Journal: Journal of neurochemistry 20121001

Title: Adenosine A(2A) receptor antagonists are broad facilitators of antinicotinic neuromuscular blockade monitored either with 2 Hz train-of-four or 50 Hz tetanic stimuli.

Journal: Clinical and experimental pharmacology & physiology 20121001

Title: Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes.

Journal: Journal of cellular physiology 20120901

Title: Elucidating mechanisms underlying altered renal autoregulation in diabetes.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120901

Title: A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury.

Journal: American journal of physiology. Renal physiology 20120901

Title: A role for ATP in bronchoconstriction-induced activation of guinea pig vagal intrapulmonary C-fibres.

Journal: The Journal of physiology 20120815

Title: Adenosinergic modulation of the imidazoline I₁-receptor-dependent hypotensive effect of ethanol in acute renal failure.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801

Title: Acute saline expansion increases nephron filtration and distal flow rate but maintains tubuloglomerular feedback responsiveness: role of adenosine A(1) receptors.

Journal: American journal of physiology. Renal physiology 20120801

Title: On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: role of adenosine A1 receptor.

Journal: The Journal of thoracic and cardiovascular surgery 20120701

Title: Evidence for constitutively-active adenosine receptors at mammalian motor nerve endings.

Journal: European journal of pharmacology 20120615

Title: Noninvasive limb remote ischemic preconditioning contributes neuroprotective effects via activation of adenosine A1 receptor and redox status after transient focal cerebral ischemia in rats.

Journal: Brain research 20120612

Title: Pinacidil pretreatment improves vascular reactivity after shock through PKCα and PKCε in rats.

Journal: Journal of cardiovascular pharmacology 20120601

Title: Contribution of the extracellular cAMP-adenosine pathway to dual coupling of β2-adrenoceptors to Gs and Gi proteins in mouse skeletal muscle.

Journal: The Journal of pharmacology and experimental therapeutics 20120601

Title: Coadministration of cannabinoid CB1-receptor and adenosine A1-receptor antagonists improves the acquisition of spatial memory in mice: participation of glutamatergic neurotransmission.

Journal: Behavioural pharmacology 20120601

Title: Activation of adenosine₁ receptors induces antidepressant-like, anti-impulsive effects on differential reinforcement of low-rate 72-s behavior in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20120501

Title: 3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A₂B adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20120223

Title: Neurabin scaffolding of adenosine receptor and RGS4 regulates anti-seizure effect of endogenous adenosine.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120222

Title: Endogenous adenosine contributes to renal sympathetic neurotransmission via postjunctional A1 receptor-mediated coincident signaling.

Journal: American journal of physiology. Renal physiology 20120215

Title: Alteration of purinergic neurotransmission in isolated atria of streptozotocin-induced diabetic rats.

Journal: Journal of cardiovascular pharmacology 20120201

Title: Acute down-regulation of adenosine A(1) receptor activity in status epilepticus.

Journal: Epilepsia 20120101

Title: Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses.

Journal: Scientific reports 20120101

Title: Combined contribution of endothelial relaxing autacoides in the rat femoral artery response to CPCA: an adenosine A2 receptor agonist.

Journal: TheScientificWorldJournal 20120101

Title: Importance of GluA1 subunit-containing AMPA glutamate receptors for morphine state-dependency.

Journal: PloS one 20120101

Title: Inhibition of hippocampal synaptic activity by ATP, hypoxia or oxygen-glucose deprivation does not require CD73.

Journal: PloS one 20120101

Title: CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111109

Title: Presynaptic muscarinic and adenosine receptors are involved in 2 Hz-induced train-of-four fade caused by antinicotinic neuromuscular relaxants in the rat.

Journal: Clinical and experimental pharmacology & physiology 20111101

Title: Morphine and remifentanil-induced cardioprotection: its experimental and clinical outcomes.

Journal: Korean journal of anesthesiology 20111101

Title: A₁ receptors inhibit glutamate release in rat medullary dorsal horn neurons.

Journal: Neuroreport 20111005

Title: Guanine-induced inhibition of renal Na(+)-ATPase activity: evidence for the involvement of the Gi protein-coupled receptor.

Journal: Archives of biochemistry and biophysics 20110915

Title: Adenosine A₂A and A₂B receptors are both required for adenosine A₁ receptor-mediated cardioprotection.

Journal: American journal of physiology. Heart and circulatory physiology 20110901

Title: Inhibitory effect of schisandrin on spontaneous contraction of isolated rat colon.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110815

Title: 2',3'-cAMP, 3'-AMP, and 2'-AMP inhibit human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors.

Journal: American journal of physiology. Heart and circulatory physiology 20110801

Title: Small-animal PET study of adenosine A(1) receptors in rat brain: blocking receptors and raising extracellular adenosine.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110801

Title: New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20110728

Title: Expression of human equilibrative nucleoside transporter 1 in mouse neurons regulates adenosine levels in physiological and hypoxic-ischemic conditions.

Journal: Journal of neurochemistry 20110701

Title: Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing.

Journal: The European journal of neuroscience 20110701

Title: Glucose-induced intestinal vasodilation via adenosine A1 receptors requires nitric oxide but not K(+)(ATP) channels.

Journal: The Journal of surgical research 20110615

Title: Endogenous adenosine A1 receptor activation underlies the transient post-ischemic rhythmic delta EEG activity.

Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20110601

Title: Functional selectivity of adenosine receptor ligands.

Journal: Purinergic signalling 20110601

Title: [Sedative, hypnotic and anticonvulsive effects of an adenosine analogue WS090501].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110601

Title: Calcium microdomains near R-type calcium channels control the induction of presynaptic long-term potentiation at parallel fiber to purkinje cell synapses.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110406

Title: The role of extracellular adenosine in chemical neurotransmission in the hippocampus and Basal Ganglia: pharmacological and clinical aspects.

Journal: Current topics in medicinal chemistry 20110401

Title: Adenosine modulates the excitability of layer II stellate neurons in entorhinal cortex through A1 receptors.

Journal: Hippocampus 20110301

Title: Adenosine A2 receptors are involved in the activation of ATP-sensitive K+ currents during metabolic inhibition in guinea pig ventricular myocytes.

Journal: Canadian journal of physiology and pharmacology 20110301

Title: Adenosine reduces GABAergic IPSC frequency via presynaptic A₁ receptors in hypothalamic paraventricular neurons projecting to rostral ventrolateral medulla.

Journal: Neuroscience letters 20110218

Title: Discovery of phosphoric acid mono-{2-[(E/Z)-4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-benzoylimino]-thiazol-3-ylmethyl} ester (Lu AA47070): a phosphonooxymethylene prodrug of a potent and selective hA(2A) receptor antagonist.

Journal: Journal of medicinal chemistry 20110210

Title: Action-potential modulation during axonal conduction.

Journal: Science (New York, N.Y.) 20110204

Title: Synergistic action of hypoosmolarity and glutamine in inducing acute swelling of retinal glial (Müller) cells.

Journal: Glia 20110201

Title: Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans.

Journal: Diabetes 20110201

Title: Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20110127

Title: Functional and morphological examinations of P1A1 purinoceptors in the normal and inflamed urinary bladder of the rat.

Journal: Autonomic neuroscience : basic & clinical 20110120

Title: Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis.

Journal: European journal of pharmacology 20110115

Title: Blockade of adenosine A(1) receptors prevents methylphenidate-induced impairment of object recognition task in adult mice.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20110115

Title: A role for adenosine A(1) receptor blockade in the ability of caffeine to promote MDMA 'Ecstasy'-induced striatal dopamine release.

Journal: European journal of pharmacology 20110110

Title: Involvement of adenosine signaling in controlling the release of ghrelin from the mouse stomach.

Journal: The Journal of pharmacology and experimental therapeutics 20110101

Title: Autocrine signaling via A(1) adenosine receptors causes downregulation of M(2) receptors in adult rat atrial myocytes in vitro.

Journal: Pflugers Archiv : European journal of physiology 20110101

Title: Short-term regulation of adiponectin secretion in rat adipocytes.

Journal: Physiological research 20110101

Title: Renal effects of the novel selective adenosine A1 receptor blocker SLV329 in experimental liver cirrhosis in rats.

Journal: PloS one 20110101

Title: Selective attenuation of norepinephrine release and stress-induced heart rate increase by partial adenosine A1 agonism.

Journal: PloS one 20110101

Title: A new series of 2-alkoxy(aralkoxy)-[1,2,4]triazolo[1,5-a]quinazolin-5-ones as adenosine receptor antagonists.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: The Effect of Cordycepin on Steroidogenesis and Apoptosis in MA-10 Mouse Leydig Tumor Cells.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: GABA(A) Receptors: Post-Synaptic Co-Localization and Cross-Talk with Other Receptors.

Journal: Frontiers in cellular neuroscience 20110101

Title: Effects of adenosine A(1) receptor antagonism on insulin secretion from rat pancreatic islets.

Journal: Physiological research 20110101

Title: The role of muscarinic receptors in the beneficial effects of adenosine against myocardial reperfusion injury in rats.

Journal: PloS one 20110101

Title: A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release.

Journal: Arthritis research & therapy 20110101

Title: Caffeine acts via A1 adenosine receptors to disrupt embryonic cardiac function.

Journal: PloS one 20110101

Title: A1 receptors self-regulate adenosine release in the striatum: evidence of autoreceptor characteristics.

Journal: Neuroscience 20101229

Title: Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors.

Journal: The Journal of physiology 20101215

Title: Adenosine receptor regulation of coronary blood flow in Ossabaw miniature swine.

Journal: The Journal of pharmacology and experimental therapeutics 20101201

Title: Differential effects of adenosine A1 receptor on pain-related behavior in normal and nerve-injured rats.

Journal: Brain research 20101118

Title: Pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as selective human A(1) adenosine receptor ligands.

Journal: Bioorganic & medicinal chemistry 20101115

Title: Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway.

Journal: Pain 20101101

Title: Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relationships.

Journal: Bioorganic & medicinal chemistry 20101101

Title: Adenosine A1 receptors are modified by acute treatment with methylphenidate in adult mice.

Journal: Brain research 20101021

Title: Deletion of aquaporin-4 renders retinal glial cells more susceptible to osmotic stress.

Journal: Journal of neuroscience research 20101001

Title: Cooperative cardioprotection through adenosine A1 and A2A receptor agonism in ischemia-reperfused isolated mouse heart.

Journal: Journal of cardiovascular pharmacology 20101001

Title: Differential effects of selective adenosine antagonists on the effort-related impairments induced by dopamine D1 and D2 antagonism.

Journal: Neuroscience 20100929

Title: Adenosine A1 receptor agonists reduce hyperalgesia after spinal cord injury in rats.

Journal: Spinal cord 20100901

Title: Delineating the mode of action of adenosine A1 receptor allosteric modulators.

Journal: Molecular pharmacology 20100901

Title: Adenosine drives recycled vesicles to a slow-release pool at the mouse neuromuscular junction.

Journal: The European journal of neuroscience 20100901

Title: Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods.

Journal: European journal of medicinal chemistry 20100801

Title: Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100701

Title: Effects of adenosine receptor antagonists on survival in amitriptyline-poisoned mice.

Journal: Drug and chemical toxicology 20100701

Title: Extracellular 2,3-cyclic adenosine monophosphate is a potent inhibitor of preglomerular vascular smooth muscle cell and mesangial cell growth [corrected].

Journal: Hypertension (Dallas, Tex. : 1979) 20100701

Title: Adenosine A(1) receptor agonist N(6)-cyclohexyl-adenosine induced phosphorylation of delta opioid receptor and desensitization of its signaling.

Journal: Acta pharmacologica Sinica 20100701

Title: Excitatory synaptic transmission in the spinal substantia gelatinosa is under an inhibitory tone of endogenous adenosine.

Journal: Neuroscience letters 20100614

Title: Extracellular 3',5'-cAMP-adenosine pathway inhibits glomerular mesangial cell growth.

Journal: The Journal of pharmacology and experimental therapeutics 20100601

Title: Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601

Title: Acute stress impairs hippocampal mossy fiber-CA3 long-term potentiation by enhancing cAMP-specific phosphodiesterase 4 activity.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601

Title: P2X(1) receptor blockade inhibits whole kidney autoregulation of renal blood flow in vivo.

Journal: American journal of physiology. Renal physiology 20100601

Title: Role of wake-promoting basal forebrain and adenosinergic mechanisms in sleep-promoting effects of ethanol.

Journal: Alcoholism, clinical and experimental research 20100601

Title: Physical Characterization of 1,3-dipropyl-8-cyclopentylxanthine (CPX).

Journal: AAPS PharmSciTech 20100601

Title: Novel N2-substituted pyrazolo[3,4-d]pyrimidine adenosine A3 receptor antagonists: inhibition of A3-mediated human glioblastoma cell proliferation.

Journal: Journal of medicinal chemistry 20100527

Title: Adenosine receptor agonists affect taurine release from mouse brain stem slices in ischemia.

Journal: Amino acids 20100501

Title: Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats contributes to the induction of persistent LTD via an adenosine-A1 receptor-regulated mechanism.

Journal: Cerebral cortex (New York, N.Y. : 1991) 20100501

Title: Synthesis and theoretical studies on energetics of novel N- and O- perfluoroalkyl triazole tagged thienopyrimidines--their potential as adenosine receptor ligands.

Journal: European journal of medicinal chemistry 20100501

Title: Modulation of A1 adenosine receptor expression by cell aggregation and long-term activation of A2a receptors in cultures of avian retinal cells: involvement of the cyclic AMP/PKA pathway.

Journal: Journal of neurochemistry 20100501

Title: Adenosine activates a2b receptors and enhances chloride secretion in kidney inner medullary collecting duct cells.

Journal: Hypertension (Dallas, Tex. : 1979) 20100501

Title: Chronic morphine treatment impaired hippocampal long-term potentiation and spatial memory via accumulation of extracellular adenosine acting on adenosine A1 receptors.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100407

Title: Antagonist selective modulation of adenosine A1 and A3 receptor pharmacology by the food dye Brilliant Black BN: evidence for allosteric interactions.

Journal: Molecular pharmacology 20100401

Title: Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels.

Journal: Journal of neurochemistry 20100401

Title: Adenosinergic modulation of neuronal activity in the pond snail Lymnaea stagnalis.

Journal: The Journal of experimental biology 20100401

Title: Glutamate-induced depression of EPSP-spike coupling in rat hippocampal CA1 neurons and modulation by adenosine receptors.

Journal: The European journal of neuroscience 20100401

Title: 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20100315

Title: Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells.

Journal: Journal of neurochemistry 20100301

Title: Adenosine A(1) receptor mediated suppression of adrenal activity in near-term fetal sheep.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100301

Title: Peripheral origin of IL-1beta production in the rodent hippocampus under in vivo systemic bacterial lipopolysaccharide (LPS) challenge and its regulation by P2X(7) receptors.

Journal: Journal of neuroimmunology 20100226

Title: Adenosine mediated desensitization of cAMP signaling enhances T-cell responses.

Journal: European journal of immunology 20100201

Title: Oral tremor induced by the muscarinic agonist pilocarpine is suppressed by the adenosine A2A antagonists MSX-3 and SCH58261, but not the adenosine A1 antagonist DPCPX.

Journal: Pharmacology, biochemistry, and behavior 20100201

Title: Compensatory upregulation of the adenosine system following phenylephrine-induced hypertrophy in cultured rat ventricular myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20100201

Title: Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands.

Journal: British journal of pharmacology 20100201

Title: The stimulatory effects of caffeine with oseltamivir (Tamiflu) on light-dark behavior and open-field behavior in mice.

Journal: Neuroscience letters 20100122

Title: Control of cannabinoid CB1 receptor function on glutamate axon terminals by endogenous adenosine acting at A1 receptors.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100113

Title: Predominance of adenosine excitatory over inhibitory effects on transmission at the neuromuscular junction of infant rats.

Journal: The Journal of pharmacology and experimental therapeutics 20100101

Title: Caffeine and an adenosine A(2A) receptor antagonist prevent memory impairment and synaptotoxicity in adult rats triggered by a convulsive episode in early life.

Journal: Journal of neurochemistry 20100101

Title: Caffeine and a selective adenosine A2A receptor antagonist induce sensitization and cross-sensitization behavior associated with increased striatal dopamine in mice.

Journal: Journal of biomedical science 20100101

Title: Bradykinin and adenosine receptors mediate desflurane induced postconditioning in human myocardium: role of reactive oxygen species.

Journal: BMC anesthesiology 20100101

Title: The impact of adenosine and an A2A adenosine receptor agonist on the ACh-induced increase in intracellular calcium of the glomus cells of the cat carotid body.

Journal: Brain research 20091208

Title: Long-term synaptic plasticity is impaired in rats with lesions of the ventrolateral preoptic nucleus.

Journal: The European journal of neuroscience 20091203

Title: Design, synthesis and biological evaluation of a bivalent micro opiate and adenosine A1 receptor antagonist.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Adenosine A(1) receptors selectively target protein kinase C isoforms to the caveolin-rich plasma membrane in cardiac myocytes.

Journal: Biochimica et biophysica acta 20091201

Title: Cannabinoid CB(1) and adenosine A(1) receptors independently inhibit hippocampal synaptic transmission.

Journal: European journal of pharmacology 20091125

Title: Absence of adenosine-mediated aortic relaxation in A(2A) adenosine receptor knockout mice.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivity.

Journal: The Journal of pharmacology and experimental therapeutics 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Suppression of GABA input by A1 adenosine receptor activation in rat cerebellar granule cells.

Journal: Neuroscience 20090915

Title: Adenosine-evoked hyperpolarization of retinal ganglion cells is mediated by G-protein-coupled inwardly rectifying K+ and small conductance Ca2+-activated K+ channel activation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090909

Title: A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells.

Journal: American journal of physiology. Heart and circulatory physiology 20090901

Title: Intracellular acidification causes adenosine release during states of hyperexcitability in the hippocampus.

Journal: Journal of neurophysiology 20090901

Title: Fructose-1,6-bisphosphate reduces inflammatory pain-like behaviour in mice: role of adenosine acting on A1 receptors.

Journal: British journal of pharmacology 20090901

Title: Inhibition of renal Na+-ATPase activity by inosine is mediated by A1 receptor-induced inhibition of the cAMP signaling pathway.

Journal: Archives of biochemistry and biophysics 20090901

Title: Adenosine and the auditory system.

Journal: Current neuropharmacology 20090901

Title: Negative crosstalk between M1 and M2 muscarinic autoreceptors involves endogenous adenosine activating A1 receptors at the rat motor endplate.

Journal: Neuroscience letters 20090814

Title: Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse.

Journal: American journal of physiology. Heart and circulatory physiology 20090801

Title: Differential actions of adenosine A1 and A2A antagonists on the effort-related effects of dopamine D2 antagonism.

Journal: Behavioural brain research 20090719

Title: Impaired glial buffering hampers antidromic conduction of CA1 neurons during hypoxia.

Journal: Brain research 20090714

Title: Adenosine A1 receptors presynaptically modulate excitatory synaptic input onto subiculum neurons.

Journal: Brain research 20090714

Title: Caffeine and a selective adenosine A2A receptor antagonist induce reward and sensitization behavior associated with increased phospho-Thr75-DARPP-32 in mice.

Journal: Psychopharmacology 20090601

Title: Activation of adenosine(1) (A(1)) receptors suppresses head shakes induced by a serotonergic hallucinogen in rats.

Journal: Neuropharmacology 20090601

Title: Adenosine deamination to inosine in isolated basolateral membrane from kidney proximal tubule: implications for modulation of the membrane-associated protein kinase A.

Journal: Archives of biochemistry and biophysics 20090601

Title: Adenosine and adenosine receptors: Newer therapeutic perspective.

Journal: Indian journal of pharmacology 20090601

Title: Synthesis of a series of 8-(substituted-phenyl)xanthines and a study on the effects of substitution pattern of phenyl substituents on affinity for adenosine A(1) and A(2A) receptors.

Journal: European journal of medicinal chemistry 20090501

Title: The adenosine A2A antagonist MSX-3 reverses the effects of the dopamine antagonist haloperidol on effort-related decision making in a T-maze cost/benefit procedure.

Journal: Psychopharmacology 20090501

Title: Regulation of somatostatin release by adenosine in the mouse stomach.

Journal: The Journal of pharmacology and experimental therapeutics 20090501

Title: Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine.

Journal: Journal of cardiovascular pharmacology 20090501

Title: Does adenosine A(1) receptor stimulation causes QRS prolongation by blocking beta adrenergic receptors in amitriptyline poisoning?

Journal: Toxicology letters 20090425

Title: Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a new scaffold to develop potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.

Journal: Journal of medicinal chemistry 20090423

Title: N6-Cycloalkyl- and N6-bicycloalkyl-C5'(C2')-modified adenosine derivatives as high-affinity and selective agonists at the human A1 adenosine receptor with antinociceptive effects in mice.

Journal: Journal of medicinal chemistry 20090423

Title: Noradrenergic control of associative synaptic plasticity by selective modulation of instructive signals.

Journal: Neuron 20090416

Title: A1 and A2a receptors mediate inhibitory effects of adenosine on the motor activity of human colon.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090401

Title: Characterization of the A2B adenosine receptor from mouse, rabbit, and dog.

Journal: The Journal of pharmacology and experimental therapeutics 20090401

Title: Early renal post-ischaemic tissue damage and dysfunction with contribution of A1-adenosine receptor activation in rat.

Journal: Nephrology (Carlton, Vic.) 20090401

Title: 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands.

Journal: Bioorganic & medicinal chemistry 20090401

Title: Endogenous activation of adenosine A1 receptors promotes post-ischemic electrocortical burst suppression.

Journal: Neuroscience 20090331

Title: Allosteric modulation of adenosine receptors.

Journal: Purinergic signalling 20090301

Title: Adenosine A1 and A2a receptors modulate insulinemia, glycemia, and lactatemia in fetal sheep.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090301

Title: Adenosine receptor antagonists improve short-term object-recognition ability of spontaneously hypertensive rats: a rodent model of attention-deficit hyperactivity disorder.

Journal: Behavioural pharmacology 20090301

Title: Mechanisms of glycine release in mouse brain stem slices.

Journal: Neurochemical research 20090201

Title: Adenosine as an endogenous regulating factor of hippocampal sharp waves.

Journal: Hippocampus 20090201

Title: Caffeine modulates TNF-alpha production by cord blood monocytes: the role of adenosine receptors.

Journal: Pediatric research 20090201

Title: Relative contribution of ecto-ATPase and ecto-ATPDase pathways to the biphasic effect of ATP on acetylcholine release from myenteric motoneurons.

Journal: British journal of pharmacology 20090201

Title: Adenosine A(1) and A(2A) receptors in mouse prefrontal cortex modulate acetylcholine release and behavioral arousal.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090121

Title: Brainstem adenosine A1 receptor signaling masks phosphorylated extracellular signal-regulated kinase 1/2-dependent hypotensive action of clonidine in conscious normotensive rats.

Journal: The Journal of pharmacology and experimental therapeutics 20090101

Title: Adenosine A1 and A3 receptor agonists inhibit nonadrenergic, noncholinergic relaxations in the guinea pig isolated trachea.

Journal: Respiration; international review of thoracic diseases 20090101

Title: Effects of adenosine A1 receptor antagonism on lipogenesis and lipolysis in isolated rat adipocytes.

Journal: Physiological research 20090101

Title: Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors.

Journal: British journal of pharmacology 20090101

Title: Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception.

Journal: PloS one 20090101

Title: Antidipsogenic effects of central adenosine-5'-triphosphate.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20090101

Title: Drug-eluting stent for delivery of signal pathway-specific 1,3-dipropyl-8-cyclopentyl xanthine.

Journal: Molecular pharmaceutics 20090101

Title: Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in vivo.

Journal: PloS one 20090101

Title: Involvement of A(1) adenosine receptors in osmotic volume regulation of retinal glial cells in mice.

Journal: Molecular vision 20090101

Title: Presynaptic M1, M2, and A1 receptors play roles in tetanic fade induced by pancuronium or cisatracurium.

Journal: Journal of anesthesia 20090101

Title: Purinergic mechanosensory transduction and visceral pain.

Journal: Molecular pain 20090101

Title: Adenosine modulates alpha2-adrenergic receptors within specific subnuclei of the nucleus tractus solitarius in normotensive and spontaneously hypertensive rats.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20081201

Title: The potential role of the nodose ganglion adenosine A1 receptor in regulation of breathing in anaesthetized rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20081201

Title: Tianeptine: an antidepressant with memory-protective properties.

Journal: Current neuropharmacology 20081201

Title: cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.

Journal: Journal of medicinal chemistry 20081127

Title: Adenosine modulates excitatory synaptic transmission and suppresses neuronal death induced by ischaemia in rat spinal motoneurones.

Journal: Pflugers Archiv : European journal of physiology 20081101

Title: MDA-MB-231 produces ATP-mediated ICAM-1-dependent facilitation of the attachment of carcinoma cells to human lymphatic endothelial cells.

Journal: American journal of physiology. Cell physiology 20081101

Title: Adenosine and adenosine uptake inhibitors potentiate the neuromuscular blocking action of rocuronium mediated by adenosine A(1) receptors in isolated rat diaphragms.

Journal: Acta anaesthesiologica Scandinavica 20081101

Title: Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage.

Journal: European journal of pharmacology 20081031

Title: The effects of adenosine A2A receptor antagonists on haloperidol-induced movement disorders in primates.

Journal: Psychopharmacology 20081001

Title: Activation of adenosine A1 receptor-induced neural stem cell proliferation via MEK/ERK and Akt signaling pathways.

Journal: Journal of neuroscience research 20081001

Title: Correlation of intrinsic optical signal, cerebral blood flow, and evoked potentials during activation of rat somatosensory cortex.

Journal: Journal of neurosurgery 20081001

Title: Selective inhibitory effect of adenosine A1 receptor agonists on the proliferation of human tumor cell lines.

Journal: Iranian biomedical journal 20081001

Title: Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924

Title: Adenosine receptor subtypes in the airways responses to 5'-adenosine monophosphate inhalation of sensitized guinea-pigs.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20080901

Title: 2-Amino-6-furan-2-yl-4-substituted nicotinonitriles as A2A adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20080814

Title: Regional haemodynamic responses to adenosine receptor activation vary across time following lipopolysaccharide treatment in conscious rats.

Journal: British journal of pharmacology 20080801

Title: Effects of adenosine receptor antagonists on amitriptyline-induced QRS prolongation in isolated rat hearts.

Journal: Clinical toxicology (Philadelphia, Pa.) 20080801

Title: The interaction of gabapentin and N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) on mechanical allodynia in rats with a spinal nerve ligation.

Journal: Journal of Korean medical science 20080801

Title: Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.

Journal: Journal of medicinal chemistry 20080724

Title: Effect of purines on calcium-independent acetylcholine release at the mouse neuromuscular junction.

Journal: Neuroscience 20080717

Title: Ischaemic and pharmacological preconditionings protect liver via adenosine and redox status following hepatic ischaemia/reperfusion in rats.

Journal: Clinical science (London, England : 1979) 20080701

Title: Adenosine A1 receptors inhibit GABAergic transmission in rat tuberomammillary nucleus neurons.

Journal: Journal of neurochemistry 20080701

Title: Adenosine induces a cholinergic tracheal reflex contraction in guinea pigs in vivo via an adenosine A1 receptor-dependent mechanism.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080701

Title: Sex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist.

Journal: Alcoholism, clinical and experimental research 20080701

Title: Adenosine A1 receptor activation mediates NMDA receptor activity in a pertussis toxin-sensitive manner during normoxia but not anoxia in turtle cortical neurons.

Journal: Brain research 20080605

Title: Endogenous A1 adenosine receptors protect against hepatic ischemia reperfusion injury in mice.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080601

Title: Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line.

Journal: American journal of physiology. Heart and circulatory physiology 20080601

Title: Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20080601

Title: Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20080601

Title: Activity of adenosine receptors type 1 Is required for CX3CL1-mediated neuroprotection and neuromodulation in hippocampal neurons.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20080601

Title: Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080515

Title: Caffeine and a selective adenosine A(2B) receptor antagonist but not imidazoline receptor antagonists modulate antinociception induced by diphenyl diselenide in mice.

Journal: Neuroscience letters 20080509

Title: Adenosine-mediated alteration of vascular reactivity and inflammation in a murine model of asthma.

Journal: American journal of physiology. Heart and circulatory physiology 20080501

Title: Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats is regulated by adenosine A1 receptors.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080430

Title: Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.

Journal: European journal of pharmacology 20080414

Title: Up-regulation of adenosine receptors in the frontal cortex in Alzheimer's disease.

Journal: Brain pathology (Zurich, Switzerland) 20080401

Title: A positive inotropic effect of ATP in the human cardiac atrium.

Journal: American journal of physiology. Heart and circulatory physiology 20080401

Title: Administration of phosphodiesterase inhibitors and an adenosine A1 receptor antagonist induces phrenic nerve recovery in high cervical spinal cord injured rats.

Journal: Experimental neurology 20080401

Title: Changes in the control of gastric motor activity during metamorphosis in the amphibian Xenopus laevis, with special emphasis on purinergic mechanisms.

Journal: The Journal of experimental biology 20080401

Title: Derivatives of 4-amino-6-hydroxy-2-mercaptopyrimidine as novel, potent, and selective A3 adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20080327

Title: A new generation of adenosine receptor antagonists: from di- to trisubstituted aminopyrimidines.

Journal: Bioorganic & medicinal chemistry 20080315

Title: Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats.

Journal: The international journal of neuropsychopharmacology 20080301

Title: Synthesis and adenosine receptor binding studies of some novel triazolothienopyrimidines.

Journal: European journal of medicinal chemistry 20080301

Title: Adenosine receptor ligands protect against a combination of apoptotic and necrotic cell death in cerebellar granule neurons.

Journal: Experimental brain research 20080301

Title: Alcohol related changes in regulation of NMDA receptor functions.

Journal: Current neuropharmacology 20080301

Title: Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy.

Journal: Journal of medicinal chemistry 20080214

Title: Stimulation of adenosine A2A receptor inhibits LPS-induced expression of intercellular adhesion molecule 1 and production of TNF-alpha in human peripheral blood mononuclear cells.

Journal: Shock (Augusta, Ga.) 20080201

Title: Cloning and functional expression of a novel Gi protein-coupled receptor for adenine from mouse brain.

Journal: Molecular pharmacology 20080201

Title: Visualisation of the effects of dilazep on rat afferent and efferent arterioles in vivo.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080201

Title: A1 and A2A receptor activation by endogenous adenosine is required for VIP enhancement of K+ -evoked [3H]-GABA release from rat hippocampal nerve terminals.

Journal: Neuroscience letters 20080117

Title: Ozone oxidative preconditioning is mediated by A1 adenosine receptors in a rat model of liver ischemia/ reperfusion.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080101

Title: Connexins 37 and 40 transduce purinergic signals mediating renal autoregulation.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080101

Title: Renal interstitial adenosine is increased in angiotensin II-induced hypertensive rats.

Journal: American journal of physiology. Renal physiology 20080101

Title: Effect of glutamate intake during gestation on adenosine A(1) receptor/adenylyl cyclase pathway in both maternal and fetal rat brain.

Journal: Journal of neurochemistry 20080101

Title: Tuning adenosine A1 and A2A receptors activation mediates L-citrulline-induced inhibition of [3H]-acetylcholine release depending on nerve stimulation pattern.

Journal: Neurochemistry international 20080101

Title: Anti-inflammatory preconditioning by agonists of adenosine A1 receptor.

Journal: PloS one 20080101

Title: Effect of the pyridoindole SMe1EC2 and compounds affecting A(1) and A(2A) adenosine receptors in rat hippocampus under ischemia in vitro.

Journal: Pharmacological reports : PR 20080101

Title: Rhythm generation by the pre-Bötzinger complex in medullary slice and island preparations: effects of adenosine A(1) receptor activation.

Journal: BMC neuroscience 20080101

Title: A role of p38 mitogen-activated protein kinase in adenosine A₁ receptor-mediated synaptic depotentiation in area CA1 of the rat hippocampus.

Journal: Molecular brain 20080101

Title: Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats.

Journal: Molecular pain 20080101

Title: [Influence of the antagonist of adenosine A1 receptors, 8-cyclopentyl-1 ,3-dipropylxanthine, upon the anticonvulsant activity of antiepileptic drugs in mice].

Journal: Przeglad lekarski 20080101

Title: Protective effect of adenosine in diabetic neuropathic pain is mediated through adenosine A1-receptors.

Journal: Indian journal of physiology and pharmacology 20080101

Title: The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors.

Journal: Behavioural brain research 20071211

Title: Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury.

Journal: American journal of physiology. Heart and circulatory physiology 20071201

Title: C-Jun N-terminal kinase regulates adenosine A1 receptor-mediated synaptic depression in the rat hippocampus.

Journal: Neuropharmacology 20071201

Title: Up-regulation of adenosine A1 receptors in frontal cortex from Pick's disease cases.

Journal: The European journal of neuroscience 20071201

Title: Adenosine A1 receptor-mediated inhibition of dopamine release from rat striatal slices is modulated by D1 dopamine receptors.

Journal: The European journal of neuroscience 20071201

Title: 5-amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a versatile scaffold to obtain potent and selective A3 adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20071115

Title: Offsetting of aberrations associated with seizure proneness in rat hippocampus area CA1 by theta pulse stimulation-induced activity pattern.

Journal: Neuroscience 20071109

Title: Hexarelin suppresses cardiac fibroblast proliferation and collagen synthesis in rat.

Journal: American journal of physiology. Heart and circulatory physiology 20071101

Title: Adenosine A(1) receptor mediates delayed cardioprotective effect of sildenafil in mouse.

Journal: Journal of molecular and cellular cardiology 20071101

Title: Theophylline inhibits free oxygen radicals production by human monocytes via phosphodiesterase inhibition.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071101

Title: Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus.

Journal: Neuroscience 20071012

Title: Modelling the restoration of wild-type dynamic behaviour in DeltaF508-CFTR NBD1 by 8-cyclopentyl-1,3-dipropylxanthine.

Journal: Journal of molecular graphics & modelling 20071001

Title: Modulation of postsynaptic potentials in rat cortical neurons by valerian extracts macerated with different alcohols: involvement of adenosine A(1)- and GABA(A)-receptors.

Journal: Phytotherapy research : PTR 20071001

Title: Influence of adenosine A(1)-receptor blockade and vagotomy on the gasping and heart rate response to hypoxia in rats during early postnatal maturation.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20071001

Title: Caffeine and accumbens shell dopamine.

Journal: Journal of neurochemistry 20071001

Title: Dual acting antioxidant A1 adenosine receptor agonists.

Journal: Bioorganic & medicinal chemistry letters 20071001

Title: Pharmacologic characterization of novel adenosine A2A receptor agonists in equine neutrophils.

Journal: American journal of veterinary research 20070901

Title: Ectonucleotidases in Müller glial cells of the rodent retina: Involvement in inhibition of osmotic cell swelling.

Journal: Purinergic signalling 20070901

Title: New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.

Journal: Journal of medicinal chemistry 20070823

Title: Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines.

Journal: European journal of pharmacology 20070813

Title: Determination of adenosine effects and adenosine receptors in murine corpus cavernosum.

Journal: The Journal of pharmacology and experimental therapeutics 20070801

Title: The adenosine A1 receptor antagonist SLV320 reduces myocardial fibrosis in rats with 5/6 nephrectomy without affecting blood pressure.

Journal: British journal of pharmacology 20070801

Title: Activation of the A1 adenosine receptor increases insulin-stimulated glucose transport in isolated rat soleus muscle.

Journal: Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20070801

Title: Co-localization and functional cross-talk between A1 and P2Y1 purine receptors in rat hippocampus.

Journal: The European journal of neuroscience 20070801

Title: Presynaptic adenosine A1 receptors modulate excitatory synaptic transmission in the posterior piriform cortex in rats.

Journal: Brain research 20070702

Title: Adenosine stimulates the basolateral 50 pS K channels in the thick ascending limb of the rat kidney.

Journal: American journal of physiology. Renal physiology 20070701

Title: ATP modulates the release of noradrenaline through two different prejunctional receptors on the adrenergic nerves of rat prostate.

Journal: Clinical and experimental pharmacology & physiology 20070701

Title: L-citrulline inhibits [3H]acetylcholine release from rat motor nerve terminals by increasing adenosine outflow and activation of A1 receptors.

Journal: British journal of pharmacology 20070601

Title: Endogenous expression of adenosine A1, A2 and A3 receptors in rat C6 glioma cells.

Journal: Neurochemical research 20070601

Title: Activity-dependent depression of local excitatory connections in the CA1 region of mouse hippocampus.

Journal: Journal of neurophysiology 20070601

Title: Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices.

Journal: Purinergic signalling 20070601

Title: Staurosporine-induced apoptosis in astrocytes is prevented by A1 adenosine receptor activation.

Journal: Neuroscience letters 20070511

Title: The enhancement of dopamine D1 receptor desensitization by adenosine A1 receptor activation.

Journal: European journal of pharmacology 20070507

Title: Developmental changes of purinergic control of intestinal motor activity during metamorphosis in the African clawed frog, Xenopus laevis.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070501

Title: Role of adenosine receptor subtypes in rat jejunum in unfed state versus glucose-induced hyperemia.

Journal: The Journal of surgical research 20070501

Title: Suppression of reactive oxygen species production enhances neuronal survival in vitro and in vivo in the anoxia-tolerant turtle Trachemys scripta.

Journal: Journal of neurochemistry 20070501

Title: Ischemic postconditioning reduces infarct size by activation of A1 receptors and K+(ATP) channels in both normal and hypercholesterolemic rabbits.

Journal: Journal of cardiovascular pharmacology 20070501

Title: Reduced basal and lipopolysaccharide-stimulated adenosine A1 receptor expression in the brain of nuclear factor-kappaB p50-/- mice.

Journal: Neuroscience 20070425

Title: Disruption of adenosinergic modulation of ventilation at rest and during hypercapnia by neonatal caffeine in young rats: role of adenosine A(1) and A(2A) receptors.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070401

Title: Antilipolytic activity of a novel partial A1 adenosine receptor agonist devoid of cardiovascular effects: comparison with nicotinic acid.

Journal: The Journal of pharmacology and experimental therapeutics 20070401

Title: Does nitric oxide modulate transmitter release at the mammalian neuromuscular junction?

Journal: Clinical and experimental pharmacology & physiology 20070401

Title: Mechanisms of direct peritoneal resuscitation-mediated splanchnic hyperperfusion following hemorrhagic shock.

Journal: Shock (Augusta, Ga.) 20070401

Title: Synergistic effects of adenosine A2A antagonist and L-DOPA on rotational behaviors in 6-hydroxydopamine-induced hemi-Parkinsonian mouse model.

Journal: Journal of pharmacological sciences 20070301

Title: Effect of 2-(6-cyano-1-hexyn-1-yl)adenosine on ocular blood flow in rabbits.

Journal: Life sciences 20070227

Title: 2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20070222

Title: Ischemic preconditioning modulates ischemia-reperfusion injury in the rat lung: role of adenosine receptors.

Journal: European journal of pharmacology 20070205

Title: Effects of tianeptine on onset time of pentylenetetrazole-induced seizures in mice: possible role of adenosine A1 receptors.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070201

Title: Presynaptic modulation of parallel fibre signalling to Bergmann glia.

Journal: Neuropharmacology 20070201

Title: Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus.

Journal: Neuropharmacology 20070201

Title: ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic efficacies on constitutively active mutants of the human adenosine A2B receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20070201

Title: Pretreatment with adenosine and adenosine A1 receptor agonist protects against intestinal ischemia-reperfusion injury in rat.

Journal: World journal of gastroenterology 20070128

Title: Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.

Journal: Journal of medicinal chemistry 20070111

Title: Depletion of ATP and release of presynaptic inhibition in the CA1 region of hippocampal slices during hypoglycemic hypoxia.

Journal: Neuroscience letters 20070103

Title: The A2a/A2b receptor antagonist ZM-241385 blocks the cardioprotective effect of adenosine agonist pretreatment in in vivo rat myocardium.

Journal: American journal of physiology. Heart and circulatory physiology 20070101

Title: A comparison of the antagonist affinities for the Gi- and Gs-coupled states of the human adenosine A1-receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine.

Journal: Experimental physiology 20070101

Title: Contractile activity of ATP and diadenosine tetraphosphate on urinary bladder in the rat: role of A1- and P2X-purinoceptors and nitric oxide.

Journal: Autonomic & autacoid pharmacology 20070101

Title: Effects of adenosine receptor antagonists on amitriptyline-induced vasodilation in rat isolated aorta.

Journal: Clinical toxicology (Philadelphia, Pa.) 20070101

Title: Regulation of pharmacology by hetero-oligomerization between A1 adenosine receptor and P2Y2 receptor.

Journal: Biochemical and biophysical research communications 20061215

Title: Co-modulation of acute ethanol-induced motor impairment by mouse cerebellar adenosinergic A1 and GABA(A) receptor systems.

Journal: Brain research bulletin 20061211

Title: Loss of vascular adenosine A1 receptors with age in the rat heart.

Journal: Vascular pharmacology 20061201

Title: A preliminary study on the interaction of fluvoxamine and adenosine receptor on isolated Guinea-pig atria.

Journal: The International journal of neuroscience 20061201

Title: Moderate cerebral venous congestion induces rapid cerebral protection via adenosine A1 receptor activation.

Journal: Brain research 20061129

Title: Effects of postconditioning of adenosine and acetylcholine on the ischemic isolated rat ventricular myocytes.

Journal: European journal of pharmacology 20061107

Title: NAD(P)H fluorescence transients after synaptic activity in brain slices: predominant role of mitochondrial function.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20061101

Title: Endogenous activation of adenosine A(1) receptors accelerates ischemic suppression of spontaneous electrocortical activity.

Journal: Journal of neurophysiology 20061101

Title: Flavonoids as antagonists at A1 adenosine receptors.

Journal: Phytotherapy research : PTR 20061101

Title: Nitric oxide-induced adenosine inhibition of hippocampal synaptic transmission depends on adenosine kinase inhibition and is cyclic GMP independent.

Journal: The European journal of neuroscience 20061101

Title: Intrahepatic adenosine-mediated activation of hepatorenal reflex is via A1 receptors in rats.

Journal: Canadian journal of physiology and pharmacology 20061101

Title: Novel selective antagonist radioligands for the pharmacological study of A(2B) adenosine receptors.

Journal: Purinergic signalling 20061101

Title: Activation of adenosine A1 receptor modulates dopamine D1 receptor activity in stably cotransfected human embryonic kidney 293 cells.

Journal: European journal of pharmacology 20061024

Title: Chronic activation of spinal adenosine A1 receptors results in hypersensitivity.

Journal: Neuroreport 20061023

Title: Modulation of dopamine D1 receptor signaling by adenosine A1 receptors in Sf9 cells requires expression of Gi proteins.

Journal: Neuroscience letters 20061009

Title: Activation of adenosine A1 receptors reduces anxiety-like behavior during acute ethanol withdrawal (hangover) in mice.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20061001

Title: Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells.

Journal: American journal of respiratory cell and molecular biology 20061001

Title: Adenosine sensory transduction pathways contribute to activation of the sensory irritation response to inspired irritant vapors.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20061001

Title: ST 1535: a preferential A2A adenosine receptor antagonist.

Journal: The international journal of neuropsychopharmacology 20061001

Title: Contribution of hepatic adenosine A1 receptors to renal dysfunction associated with acute liver injury in rats.

Journal: Hepatology (Baltimore, Md.) 20061001

Title: Presynaptic inhibition of spontaneous acetylcholine release mediated by P2Y receptors at the mouse neuromuscular junction.

Journal: Neuroscience 20060929

Title: Respiratory and body temperature modulation by adenosine A1 receptors in the anteroventral preoptic region during normoxia and hypoxia.

Journal: Respiratory physiology & neurobiology 20060928

Title: Increased density and synapto-protective effect of adenosine A2A receptors upon sub-chronic restraint stress.

Journal: Neuroscience 20060915

Title: Evidence for both adenosine A1 and A2A receptors activating single vagal sensory C-fibres in guinea pig lungs.

Journal: The Journal of physiology 20060901

Title: The role of adenosine in the early respiratory and cardiovascular changes evoked by chronic hypoxia in the rat.

Journal: The Journal of physiology 20060815

Title: Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum.

Journal: Neuroscience 20060811

Title: Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation.

Journal: Kidney international 20060801

Title: Inhibitory responses to exogenous adenosine in murine proximal and distal colon.

Journal: British journal of pharmacology 20060801

Title: Potentiation of adenosine A1 receptor agonist CPA-induced antinociception by paeoniflorin in mice.

Journal: Biological & pharmaceutical bulletin 20060801

Title: Improving potency, selectivity, and water solubility of adenosine A1 receptor antagonists: xanthines modified at position 3 and related pyrimido[1,2,3-cd]purinediones.

Journal: ChemMedChem 20060801

Title: [Action of AMP579 and adenosine on potassium or sodium ionic channels in isolated rat and guinea pig ventricular myocytes].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060801

Title: DPCPX-resistant hypoxic synaptic depression in the CA1 region of hippocampal slices: possible role of intracellular accumulation of monocarboxylates.

Journal: Neuroscience letters 20060731

Title: Role of A1 adenosine receptor in the regulation of coronary flow.

Journal: American journal of physiology. Heart and circulatory physiology 20060701

Title: Adenosine receptor antagonism in acute tacrolimus toxicity.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Adenosine A2A receptor mediated protective effect of 2-(6-cyano-1-hexyn-1-yl)adenosine on retinal ischaemia/reperfusion damage in rats.

Journal: The British journal of ophthalmology 20060701

Title: Negative cross-talk between presynaptic adenosine and acetylcholine receptors.

Journal: The European journal of neuroscience 20060701

Title: Caffeine inhibition of rat carotid body chemoreceptors is mediated by A2A and A2B adenosine receptors.

Journal: Journal of neurochemistry 20060701

Title: 4-amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as new potent and selective human A3 adenosine receptor antagonists. synthesis, pharmacological evaluation, and ligand-receptor modeling studies.

Journal: Journal of medicinal chemistry 20060629

Title: Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20060615

Title: A1 adenosine receptor knockout mice are protected against acute radiocontrast nephropathy in vivo.

Journal: American journal of physiology. Renal physiology 20060601

Title: Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinson's disease by activation of adenosine A1 receptor.

Journal: British journal of pharmacology 20060601

Title: Valerian extract Ze 911 inhibits postsynaptic potentials by activation of adenosine A1 receptors in rat cortical neurons.

Journal: Planta medica 20060601

Title: Peripheral anti-hyperalgesia by oxcarbazepine: involvement of adenosine A1 receptors.

Journal: Die Pharmazie 20060601

Title: A novel partial agonist of the A(1)-adenosine receptor and evidence of receptor homogeneity in adipocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20060501

Title: Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.

Journal: Cardiovascular research 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Characterization of adenosine receptors in the human bladder carcinoma T24 cell line.

Journal: European journal of pharmacology 20060424

Title: Involvement of adenosine A1 and A2A receptors in (-)-linalool-induced antinociception.

Journal: Life sciences 20060418

Title: Mechanism of adenosine-induced airways obstruction in allergic guinea pigs.

Journal: British journal of pharmacology 20060401

Title: Post-hypoxic hypoperfusion is associated with suppression of cerebral metabolism and increased tissue oxygenation in near-term fetal sheep.

Journal: The Journal of physiology 20060401

Title: Radioligand binding and functional responses of ligands for human recombinant adenosine A(3) receptors.

Journal: Autonomic & autacoid pharmacology 20060401

Title: Peripheral antinociception by carbamazepine in an inflammatory mechanical hyperalgesia model in the rat: a new target for carbamazepine?

Journal: Journal of pharmacological sciences 20060401

Title: Role of the second transmembrane domain of rat adenosine A1 receptor in ligand-receptor interaction.

Journal: Biochemical pharmacology 20060314

Title: Progress in the pursuit of therapeutic adenosine receptor antagonists.

Journal: Medicinal research reviews 20060301

Title: Allosteric modulation, thermodynamics and binding to wild-type and mutant (T277A) adenosine A1 receptors of LUF5831, a novel nonadenosine-like agonist.

Journal: British journal of pharmacology 20060301

Title: NMDA-induced preconditioning attenuates synaptic plasticity in the rat hippocampus.

Journal: Brain research 20060216

Title: Activation of receptors negatively coupled to adenylate cyclase is required for induction of long-term synaptic depression at Schaffer collateral-CA1 synapses.

Journal: Journal of neurobiology 20060215

Title: Combination of adenosine A1 and A2A receptor blocking agents induces caffeine-like locomotor stimulation in mice.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060201

Title: Adenosine A1 receptor antagonist blunts urinary potassium excretion, but not renal hemodynamic effects, induced by carbonic anhydrase inhibitor in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20060201

Title: Isoflurane tolerance against focal cerebral ischemia is attenuated by adenosine A1 receptor antagonists.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060201

Title: Contractile effects of adenosine A1 and A2A receptors in isolated murine hearts.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Involvement of adenosine in the effect of fluoxetine on isolated guinea-pig atria.

Journal: Pharmacological research 20060101

Title: The cellular mechanisms by which adenosine evokes release of nitric oxide from rat aortic endothelium.

Journal: The Journal of physiology 20060101

Title: Hypoxia-induced desensitization and internalization of adenosine A1 receptors in the rat hippocampus.

Journal: Neuroscience 20060101

Title: Effects of the A 2A adenosine receptor antagonist KW6002 in the nucleus accumbens in vitro and in vivo.

Journal: Pharmacology, biochemistry, and behavior 20060101

Title: Endogenous signalling system involved in parotid gland adenosine A(1) receptor-amylase release.

Journal: Acta physiologica (Oxford, England) 20060101

Title: Involvement of peripheral adenosine A2 receptors in adenosine A1 receptor-mediated recovery of respiratory motor function after upper cervical spinal cord hemisection.

Journal: The journal of spinal cord medicine 20060101

Title: Effect of theophylline and aminophylline on transmitter release at the mammalian neuromuscular junction is not mediated by cAMP.

Journal: Clinical and experimental pharmacology & physiology 20060101

Title: 2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching.

Journal: Journal of medicinal chemistry 20051229

Title: 1,2,4-Triazolo[1,5-a]quinoxaline as a versatile tool for the design of selective human A3 adenosine receptor antagonists: synthesis, biological evaluation, and molecular modeling studies of 2-(hetero)aryl- and 2-carboxy-substituted derivatives.

Journal: Journal of medicinal chemistry 20051215

Title: Effects of urea pretreatment on the binding properties of adenosine A1 receptors.

Journal: British journal of pharmacology 20051201

Title: Adenosine-stimulated atrial natriuretic peptide release through A1 receptor subtype.

Journal: Hypertension (Dallas, Tex. : 1979) 20051201

Title: Supersensitivity of P2X receptors in cerebrocortical cell cultures after in vitro ischemia.

Journal: Journal of neurochemistry 20051201

Title: Cortical spreading depression (CSD)-induced tolerance to transient focal cerebral ischemia in halothane anesthetized rats is affected by anesthetic level but not ATP-sensitive potassium channels.

Journal: Brain research 20051116

Title: 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.

Journal: Journal of medicinal chemistry 20051103

Title: In vivo co-ordinated interactions between inhibitory systems to control glutamate-mediated hippocampal excitability.

Journal: Journal of neurochemistry 20051101

Title: Synthesis and evaluation of [11C]FR194921 as a nonxanthine-type PET tracer for adenosine A1 receptors in the brain.

Journal: Nuclear medicine and biology 20051101

Title: Inhibitory action of L-type Ca2+ current by paeoniflorin, a major constituent of peony root, in NG108-15 neuronal cells.

Journal: European journal of pharmacology 20051031

Title: Allosteric modulators affect the internalization of human adenosine A1 receptors.

Journal: European journal of pharmacology 20051017

Title: Astrocytic purinergic signaling coordinates synaptic networks.

Journal: Science (New York, N.Y.) 20051007

Title: Blockade of adenosine and dopamine receptors inhibits the development of rapid tolerance to ethanol in mice.

Journal: Psychopharmacology 20051001

Title: A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma.

Journal: The Journal of pharmacology and experimental therapeutics 20051001

Title: Neuroprotective effect of paeoniflorin on cerebral ischemic rat by activating adenosine A1 receptor in a manner different from its classical agonists.

Journal: British journal of pharmacology 20051001

Title: Adenosine down-regulates giant depolarizing potentials in the developing rat hippocampus by exerting a negative control on glutamatergic inputs.

Journal: Journal of neurophysiology 20051001

Title: Blood pressure-dependent inhibition of Renin secretion requires A1 adenosine receptors.

Journal: Hypertension (Dallas, Tex. : 1979) 20051001

Title: Cell-signaling evidence for adenosine stimulation of coronary smooth muscle proliferation via the A1 adenosine receptor.

Journal: Circulation research 20050916

Title: Persistent upregulation of mu-opioid, but not adenosine, receptors in brains of long-term withdrawn escalating dose 'binge' cocaine-treated rats.

Journal: Synapse (New York, N.Y.) 20050901

Title: Adenosine inhibits PDGF-induced growth of human glomerular mesangial cells via A(2B) receptors.

Journal: Hypertension (Dallas, Tex. : 1979) 20050901

Title: Indirect activation of adenosine A1 receptors in cultured rat hippocampal neurons by volatile anaesthetics.

Journal: European journal of anaesthesiology 20050901

Title: Isoflurane preconditioning decreases glutamate receptor overactivation-induced Purkinje neuronal injury in rat cerebellar slices.

Journal: Brain research 20050830

Title: 2-(1-Hexyn-1-yl)adenosine-induced intraocular hypertension is mediated via K+ channel opening through adenosine A2A receptor in rabbits.

Journal: European journal of pharmacology 20050822

Title: Evidence against adenosine analogues being agonists at the growth hormone secretagogue receptor.

Journal: Biochemical pharmacology 20050815

Title: Distinct molecular phenotype of malignant CD34(+) hematopoietic stem and progenitor cells in chronic myelogenous leukemia.

Journal: Oncogene 20050811

Title: Long-term depression is not modulated by ATP receptors in the rat CA1 hippocampal region.

Journal: Neuroscience letters 20050805

Title: A1 adenosine receptor knockout mice exhibit increased mortality, renal dysfunction, and hepatic injury in murine septic peritonitis.

Journal: American journal of physiology. Renal physiology 20050801

Title: Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050706

Title: Cerebral oxygenation during postasphyxial seizures in near-term fetal sheep.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050701

Title: Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.

Journal: Cardiovascular research 20050701

Title: Antagonistic interaction between adenosine A2A and dopamine D2 receptors modulates the social recognition memory in reserpine-treated rats.

Journal: Behavioural pharmacology 20050701

Title: Long-term potentiation is impaired in middle-aged rats: regional specificity and reversal by adenosine receptor antagonists.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050622

Title: ATP contributes to the generation of network-driven giant depolarizing potentials in the neonatal rat hippocampus.

Journal: The Journal of physiology 20050615

Title: Does conversion of ATP to adenosine terminate ATP-stimulated vasopressin release from hypothalamo-neurohypophyseal explants?

Journal: Brain research 20050614

Title: Rapid tolerance to focal cerebral ischemia in rats is induced by preconditioning with electroacupuncture: window of protection and the role of adenosine.

Journal: Neuroscience letters 20050601

Title: Requisite roles of A2A receptors, nitric oxide, and KATP channels in retinal arteriolar dilation in response to adenosine.

Journal: Investigative ophthalmology & visual science 20050601

Title: Adenosine A2A-receptor blockade abolishes the roll-off respiratory response to hypoxia in awake lambs.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050501

Title: A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade.

Journal: American journal of physiology. Heart and circulatory physiology 20050501

Title: Luminal adenosine stimulates chloride secretion through A1 receptor in mouse jejunum.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050501

Title: In vivo adenosine receptor preconditioning reduces myocardial infarct size via subcellular ERK signaling.

Journal: American journal of physiology. Heart and circulatory physiology 20050501

Title: Human breast cancer cell line MDA-MB-231 expresses endogenous A2B adenosine receptors mediating a Ca2+ signal.

Journal: British journal of pharmacology 20050501

Title: Enhanced antinociception by intracerebroventricularly and intrathecally-administered orexin A and B (hypocretin-1 and -2) in mice.

Journal: Peptides 20050501

Title: Activation of adenosine receptors in the posterior cingulate cortex impairs memory retrieval in the rat.

Journal: Neurobiology of learning and memory 20050501

Title: Effects of AMP579 and adenosine on L-type Ca2+ current in isolated rat ventricular myocytes.

Journal: Acta pharmacologica Sinica 20050501

Title: Blockade of adenosine A2A receptors reverses short-term social memory impairments in spontaneously hypertensive rats.

Journal: Behavioural brain research 20050430

Title: Adenosine A1 receptors modulate the discharge activities of inspiratory and biphasic expiratory neurons in the medial region of Nucleus Retrofacialis of neonatal rat in vitro.

Journal: Neuroscience letters 20050429

Title: ATP-stimulated ANP release through P1 receptor subtype.

Journal: Regulatory peptides 20050415

Title: The phosphodiesterase 3 inhibitor cilostamide enhances inotropic responses to glucagon but not to dobutamine in rat ventricular myocardium.

Journal: European journal of pharmacology 20050411

Title: Pharmacological characterisation of the adenosine receptor mediating increased ion transport in the mouse isolated trachea and the effect of allergen challenge.

Journal: British journal of pharmacology 20050401

Title: Effects of diadenosine polyphosphates on glomerular volume.

Journal: British journal of pharmacology 20050401

Title: Mechanism of vasodilation to adenosine in coronary arterioles from patients with heart disease.

Journal: American journal of physiology. Heart and circulatory physiology 20050401

Title: Adenosine agonist regulation of outward active transport of fluorescein across retinal pigment epithelium in rabbits.

Journal: Experimental eye research 20050401

Title: Adenosine receptor ligands and dizocilpine-induced antinociception in mice.

Journal: The International journal of neuroscience 20050401

Title: Involvement of adenosine A2a receptor in intraocular pressure decrease induced by 2-(1-octyn-1-yl)adenosine or 2-(6-cyano-1-hexyn-1-yl)adenosine.

Journal: Journal of pharmacological sciences 20050401

Title: GABA release modified by adenosine receptors in mouse hippocampal slices under normal and ischemic conditions.

Journal: Neurochemical research 20050401

Title: A series of ligands displaying a remarkable agonistic-antagonistic profile at the adenosine A1 receptor.

Journal: Journal of medicinal chemistry 20050324

Title: Development of spin-labeled probes for adenosine receptors.

Journal: Journal of medicinal chemistry 20050324

Title: Induction of delta-opioid receptor function in the midbrain after chronic morphine treatment.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050323

Title: Modulation of short-term social memory in rats by adenosine A1 and A(2A) receptors.

Journal: Neuroscience letters 20050316

Title: The role of extracellular adenosine in regulating mossy fiber synaptic plasticity.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050316

Title: Adenosine contributes to mu-opioid synaptic inhibition in rat substantia gelatinosa in vitro.

Journal: Neuroscience letters 20050311

Title: A 'locked-on,' constitutively active mutant of the adenosine A1 receptor.

Journal: European journal of pharmacology 20050307

Title: Acute adenosine preconditioning is mediated by p38 MAPK activation in discrete subcellular compartments.

Journal: American journal of physiology. Heart and circulatory physiology 20050301

Title: Role of A1 adenosine receptors in regulation of vascular tone.

Journal: American journal of physiology. Heart and circulatory physiology 20050301

Title: Adenosine produces nitric oxide and prevents mitochondrial oxidant damage in rat cardiomyocytes.

Journal: Cardiovascular research 20050301

Title: [Effect of adenosine A1-receptors on the respiratory rhythmical discharge activity in neonatal rat brainstem slice in vitro].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050301

Title: Reversal of neuromuscular effects of adenosine by specific adenosine A1-receptor antagonist in live rats.

Journal: The International journal of neuroscience 20050301

Title: Scavenging of nitric oxide by an antagonist of adenosine receptors.

Journal: The Journal of pharmacy and pharmacology 20050301

Title: Adenosine A1 receptors are involved in the modulation of the rhythmical respiration in neonatal rat brainstem slice in vitro.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20050225

Title: Metabotropic P2Y purinoceptor-mediated presynaptic and postsynaptic enhancement of cerebellar GABAergic transmission.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050223

Title: First visualization of adenosine A(2A) receptors in the human brain by positron emission tomography with [11C]TMSX.

Journal: Synapse (New York, N.Y.) 20050201

Title: Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum.

Journal: Journal of neurochemistry 20050201

Title: Increased nociceptive response in mice lacking the adenosine A1 receptor.

Journal: Pain 20050201

Title: Modulating effect of adenosine deaminase on function of adenosine A1 receptors.

Journal: Acta pharmacologica Sinica 20050201

Title: Effects of adenosine agonist R-phenylisopropyl-adenosine on halothane anesthesia and antinociception in rats.

Journal: Acta pharmacologica Sinica 20050201

Title: Morphine can enhance the antiallodynic effect of intrathecal R-PIA in rats with nerve ligation injury.

Journal: Anesthesia and analgesia 20050201

Title: Adenosine postsynaptically modulates supraoptic neuronal excitability.

Journal: Journal of neurophysiology 20050101

Title: Stimulation of the proximal tubule Na+-ATPase activity by adenosine A(2A) receptor.

Journal: The international journal of biochemistry & cell biology 20050101

Title: Inhibition of phenylephrine-induced cardiomyocyte hypertrophy by activation of multiple adenosine receptor subtypes.

Journal: The Journal of pharmacology and experimental therapeutics 20050101

Title: Adenosine A1 receptors and the anticonvulsant potential of drugs effective in the model of 3-nitropropionic acid-induced seizures in mice.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050101

Title: Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.

Journal: Neuroscience research 20050101

Title: Participation of adenosine system in the ketamine-induced motor activity in mice.

Journal: Pharmacological reports : PR 20050101

Title: S-nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner.

Journal: BMC cell biology 20050101

Title: Decreased adenosine receptor binding in dystonic brains of the dt(sz) mutant.

Journal: Neuroscience 20050101

Title: Long-term effect of convulsive behavior on the density of adenosine A1 and A 2A receptors in the rat cerebral cortex.

Journal: Epilepsia 20050101

Title: Modulation of seizures and synaptic plasticity by adenosinergic receptors in an experimental model of temporal lobe epilepsy induced by pilocarpine in rats.

Journal: Epilepsia 20050101

Title: Renal blood flow in sepsis.

Journal: Critical care (London, England) 20050101

Title: 2-Chloro-N6-cyclopentyladenosine enhances the anticonvulsant action of carbamazepine in the mouse maximal electroshock-induced seizure model.

Journal: Pharmacological reports : PR 20050101

Title: Isolated rat inferior mesenteric artery response to adenosine: possible participation of Na+/K+-ATPase and potassium channels.

Journal: Pharmacological reports : PR 20050101

Title: Adenosine A1/A2a receptor agonist AMP-579 induces acute and delayed preconditioning against in vivo myocardial stunning.

Journal: American journal of physiology. Heart and circulatory physiology 20041201

Title: ATP inhibits pump activity of lymph vessels via adenosine A1 receptor-mediated involvement of NO- and ATP-sensitive K+ channels.

Journal: American journal of physiology. Heart and circulatory physiology 20041201

Title: Inhibitory effects of AMP 579, a novel cardioprotective adenosine A1/A2A receptor agonist, on native IKr and cloned HERG current.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20041201

Title: Adenosine A1 receptor blockade mimics caffeine's attenuation of ethanol-induced motor incoordination.

Journal: Basic & clinical pharmacology & toxicology 20041201

Title: Anti-infarct effect of magnesium is not mediated by adenosine A1 receptors in rat globally ischaemic isolated hearts.

Journal: Clinical and experimental pharmacology & physiology 20041201

Title: Adenosine receptors involved in modulation of noradrenaline release in isolated rat tail artery.

Journal: European journal of pharmacology 20041103

Title: Cardiovascular responses to microinjection of ATP into the nucleus tractus solitarii of awake rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20041101

Title: Effects of adenosine on optic nerve head circulation in rabbits.

Journal: Experimental eye research 20041101

Title: Quantitative autoradiography of adenosine receptors and NBTI-sensitive adenosine transporters in the brains of mice deficient in the preproenkephalin gene.

Journal: Brain research 20041029

Title: The anticonvulsant action of propofol on epileptiform activity in rat hippocampal slices.

Journal: Anesthesia and analgesia 20041001

Title: Adenosine A1-receptor modulation of glutamate-induced calcium influx in rat retinal ganglion cells.

Journal: Investigative ophthalmology & visual science 20041001

Title: The in vitro and in vivo pharmacological activity of Boiga dendrophila (mangrove catsnake) venom.

Journal: Autonomic & autacoid pharmacology 20041001

Title: Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits.

Journal: European journal of pharmacology 20040919

Title: Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.

Journal: European journal of pharmacology 20040919

Title: P2X receptor activation elicits transporter-mediated noradrenaline release from rat hippocampal slices.

Journal: The Journal of pharmacology and experimental therapeutics 20040901

Title: Striatal adenosine A(2A) receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats.

Journal: Neuropharmacology 20040901

Title: Adenosine acting via A1 receptors, controls the transition to status epilepticus-like behaviour in an in vitro model of epilepsy.

Journal: Neuropharmacology 20040901

Title: 3-Morpholinylsydnonimine inhibits glutamatergic transmission in rat rostral ventrolateral medulla via peroxynitrite formation and adenosine release.

Journal: Molecular pharmacology 20040901

Title: P2X2 and P2Y1 immunofluorescence in rat neostriatal medium-spiny projection neurones and cholinergic interneurones is not linked to respective purinergic receptor function.

Journal: British journal of pharmacology 20040901

Title: Ethanol operant self-administration in rats is regulated by adenosine A2 receptors.

Journal: Alcoholism, clinical and experimental research 20040901

Title: A guinea pig hippocampal slice model of organophosphate-induced seizure activity.

Journal: The Journal of pharmacology and experimental therapeutics 20040801

Title: Role of adenosine A1 receptor in the regulation of gastrin release.

Journal: The Journal of pharmacology and experimental therapeutics 20040801

Title: Long-term potentiation is impaired in rat hippocampal slices that produce spontaneous sharp waves.

Journal: The Journal of physiology 20040801

Title: Adipocyte lipolysis, hormonal and metabolic changes in ethanol-drinking rats.

Journal: Journal of animal physiology and animal nutrition 20040801

Title: Regulation by equilibrative nucleoside transporter of adenosine outward currents in adult rat spinal dorsal horn neurons.

Journal: Brain research bulletin 20040730

Title: Histological protection against ischemia-reperfusion injury by early ischemic preconditioning in rat retina.

Journal: Brain research 20040723

Title: Changes in purine levels and adenosine receptors in kindled seizures in the rat.

Journal: Neuroreport 20040719

Title: [3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors.

Journal: Biochemical pharmacology 20040715

Title: Adenosine A1 receptors in contrast media-induced renal dysfunction in the normal rat.

Journal: European radiology 20040701

Title: 1,2,4-triazolo[4,3-a]quinoxalin-1-one moiety as an attractive scaffold to develop new potent and selective human A3 adenosine receptor antagonists: synthesis, pharmacological, and ligand-receptor modeling studies.

Journal: Journal of medicinal chemistry 20040701

Title: Adenosine A(1) receptor antagonist and mitochondrial ATP-sensitive potassium channel blocker attenuate the tolerance to focal cerebral ischemia in rats.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040701

Title: Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives.

Journal: Journal of medicinal chemistry 20040603

Title: Role of adenosine A2A receptor in the regulation of gastric somatostatin release.

Journal: The Journal of pharmacology and experimental therapeutics 20040501

Title: Presynaptic inhibition of spontaneous acetylcholine release induced by adenosine at the mouse neuromuscular junction.

Journal: British journal of pharmacology 20040501

Title: Pharmacological manipulations of ATP-dependent potassium channels and adenosine A1 receptors do not impact hippocampal ischemic preconditioning in vivo: evidence in a highly quantitative gerbil model.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040501

Title: Adenosine suppresses GABAA receptor-mediated responses in rat sacral dorsal commissural neurons.

Journal: Autonomic neuroscience : basic & clinical 20040430

Title: Injection of adenosine into the renal artery activates spontaneous activity of renal afferent nerve fibers.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20040425

Title: Inosine stimulates chemotaxis, Ca2+-transients and actin polymerization in immature human dendritic cells via a pertussis toxin-sensitive mechanism independent of adenosine receptors.

Journal: Journal of cellular physiology 20040401

Title: [Role of adenosine in intraocular pressure].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040401

Title: Adenosine A1 receptor distribution in the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20040401

Title: Repeated dosing with oral allosteric modulator of adenosine A1 receptor produces tolerance in rats with neuropathic pain.

Journal: Anesthesiology 20040401

Title: [Relation between adenosine A1 receptor and NMDA receptor on synaptic transmission in dentate gyrus of hippocampus].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040401

Title: Periodic orbit analysis reveals subtle effects of atropine on epileptiform activity in the guinea-pig hippocampal slice.

Journal: Neuroscience letters 20040311

Title: Adenosine A1 receptor agonists block the neuropathological changes in rat retrosplenial cortex after administration of the NMDA receptor antagonist dizocilpine.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040301

Title: Comparison of three different A1 adenosine receptor antagonists on infarct size and multiple cycle ischemic preconditioning in anesthetized dogs.

Journal: The Journal of pharmacology and experimental therapeutics 20040301

Title: Binding of the prototypical adenosine A(2A) receptor agonist CGS 21680 to the cerebral cortex of adenosine A(1) and A(2A) receptor knockout mice.

Journal: British journal of pharmacology 20040301

Title: Dual effects of adenosine on acetylcholine release from myenteric motoneurons are mediated by junctional facilitatory A(2A) and extrajunctional inhibitory A(1) receptors.

Journal: British journal of pharmacology 20040301

Title: Effects of 2-alkynyladenosine derivatives on intraocular pressure in rabbits.

Journal: European journal of pharmacology 20040223

Title: A1 adenosine receptor knockout mice exhibit increased renal injury following ischemia and reperfusion.

Journal: American journal of physiology. Renal physiology 20040201

Title: Hypothermic preconditioning increases survival of purkinje neurons in rat cerebellar slices after an in vitro simulated ischemia.

Journal: Anesthesiology 20040201

Title: Characteristics of taurine release induced by free radicals in mouse hippocampal slices.

Journal: Amino acids 20040201

Title: Down-regulation of rat brain adenosine A1 receptors at the end of pregnancy.

Journal: Journal of neurochemistry 20040201

Title: Chronic hypoxia up-regulates expression of adenosine A1 receptors in DDT1-MF2 cells.

Journal: Biochemical pharmacology 20040201

Title: Synthesis and biological evaluation of 2,3,5-substituted [1,2,4]thiadiazoles as allosteric modulators of adenosine receptors.

Journal: Journal of medicinal chemistry 20040129

Title: Adenosine administration produces an antidepressant-like effect in mice: evidence for the involvement of A1 and A2A receptors.

Journal: Neuroscience letters 20040123

Title: Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040121

Title: Modulation of A1 adenosine receptor signaling by peroxynitrite.

Journal: Biochemical pharmacology 20040115

Title: A1 adenosine receptor activation inhibits inflammation, necrosis, and apoptosis after renal ischemia-reperfusion injury in mice.

Journal: Journal of the American Society of Nephrology : JASN 20040101

Title: A1 and A2A adenosine receptor modulation of alpha 1-adrenoceptor-mediated contractility in human cultured prostatic stromal cells.

Journal: British journal of pharmacology 20040101

Title: Application of fluorescence correlation spectroscopy to the measurement of agonist binding to a G-protein coupled receptor at the single cell level.

Journal: Faraday discussions 20040101

Title: Modulation by adenosine of Adelta and C primary-afferent glutamatergic transmission in adult rat substantia gelatinosa neurons.

Journal: Neuroscience 20040101

Title: Involvement of adenosinergic A1 systems in the occurrence of respiratory perturbations encountered in newborns following an in utero caffeine exposure. a study on brainstem-spinal cord preparations isolated from newborn rats.

Journal: Neuroscience 20040101

Title: Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats?

Journal: Journal of toxicology. Clinical toxicology 20040101

Title: Adenosine mediates decreased cerebral metabolic rate and increased cerebral blood flow during acute moderate hypoxia in the near-term fetal sheep.

Journal: The Journal of physiology 20031215

Title: Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior.

Journal: The Journal of clinical investigation 20031215

Title: Caffeine reduces hypnotic effects of alcohol through adenosine A2A receptor blockade.

Journal: Neuropharmacology 20031201

Title: Involvement of adenosine A1 receptors in forced walking stress-induced analgesia in mice.

Journal: Methods and findings in experimental and clinical pharmacology 20031201

Title: Effect of drugs active at adenosine receptors upon chronic stress-induced hyperalgesia in rats.

Journal: European journal of pharmacology 20031128

Title: Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031126

Title: Functional expression of rat adenosine A1 receptor in the dimorphic zygomycete Mucor circinelloides.

Journal: Applied microbiology and biotechnology 20031101

Title: Activation of adenosine A1 receptor attenuates cardiac hypertrophy and prevents heart failure in murine left ventricular pressure-overload model.

Journal: Circulation research 20031017

Title: Subcellular localization of adenosine A(1) receptors in nerve terminals and synapses of the rat hippocampus.

Journal: Brain research 20031010

Title: Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction.

Journal: American journal of physiology. Heart and circulatory physiology 20031001

Title: Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.

Journal: Neuropharmacology 20031001

Title: Evaluation of 18F-CPFPX, a novel adenosine A1 receptor ligand: in vitro autoradiography and high-resolution small animal PET.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20031001

Title: Adenosine protects against angiotensin II-induced apoptosis in rat cardiocyte cultures.

Journal: Molecular and cellular biochemistry 20031001

Title: A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation.

Journal: Brain pathology (Zurich, Switzerland) 20031001

Title: Hypersensitivity of pulmonary C fibers induced by adenosine in anesthetized rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20030901

Title: Renal effects of adenosine A1-receptor blockade with 8-cyclopentyl-1,3-dipropylxanthine in hypoxemic newborn rabbits.

Journal: Pediatric research 20030901

Title: Convergent control of synaptic GABA release from rat dorsal horn neurones by adenosine and GABA autoreceptors.

Journal: The Journal of physiology 20030901

Title: Key neuroprotective role for endogenous adenosine A1 receptor activation during asphyxia in the fetal sheep.

Journal: Stroke 20030901

Title: Ectonucleotidases of the rabbit ciliary body nonpigmented epithelium.

Journal: Investigative ophthalmology & visual science 20030901

Title: Brief, repeated, oxygen-glucose deprivation episodes protect neurotransmission from a longer ischemic episode in the in vitro hippocampus: role of adenosine receptors.

Journal: British journal of pharmacology 20030901

Title: Potential of an adenosine A2A receptor antagonist [11C]TMSX for myocardial imaging by positron emission tomography: a first human study.

Journal: Annals of nuclear medicine 20030901

Title: Effects of adenosine receptor antagonists on pial arteriolar dilation during carbon dioxide inhalation.

Journal: European journal of pharmacology 20030829

Title: Antagonist pharmacology of adenosine A2B receptors from rat, guinea pig and dog.

Journal: European journal of pharmacology 20030815

Title: Diadenosine-5-phosphate exerts A1-receptor-mediated proarrhythmic effects in rabbit atrial myocardium.

Journal: British journal of pharmacology 20030801

Title: Comparison of effects of MgCl2 and Gpp(NH)p on antagonist and agonist radioligand binding to adenosine A1 receptors.

Journal: Acta pharmacologica Sinica 20030801

Title: Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.

Journal: Journal of neurophysiology 20030801

Title: Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats.

Journal: The European journal of neuroscience 20030801

Title: Adenosine and opioid receptor-mediated cardioprotection in the rat: evidence for cross-talk between receptors.

Journal: American journal of physiology. Heart and circulatory physiology 20030701

Title: Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701

Title: Mechanisms of sevoflurane-induced myocardial preconditioning in isolated human right atria in vitro.

Journal: Anesthesiology 20030701

Title: A1-receptor blockade: a novel approach for assessing myocardial viability in chronic ischemic cardiomyopathy.

Journal: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20030701

Title: Endogenous adenosine reduces glutamatergic output from rods through activation of A2-like adenosine receptors.

Journal: Journal of neurophysiology 20030701

Title: Partial adenosine A(1) receptor agonists inhibit sarin-induced epileptiform activity in the hippocampal slice.

Journal: European journal of pharmacology 20030620

Title: Adenosine-mediated synaptic depression and EPSP/spike dissociation following high potassium-induced depolarization in rat hippocampal slices.

Journal: Brain research 20030613

Title: Intraspinal adenosine induces spinal cord norepinephrine release in spinal nerve-ligated rats but not in normal or sham controls.

Journal: Anesthesiology 20030601

Title: Analysis of adenosine vascular effect in isolated rat aorta: possible role of Na+/K+-ATPase.

Journal: Pharmacology & toxicology 20030601

Title: Homo- and heteroexchange of adenine nucleotides and nucleosides in rat hippocampal slices by the nucleoside transport system.

Journal: British journal of pharmacology 20030601

Title: Caffeine analogs: effects on ryanodine-sensitive calcium-release channels and GABAA receptors.

Journal: Cellular and molecular neurobiology 20030601

Title: Free radicals potentiate the negative dromotropic effect of adenosine in guinea pig isolated heart.

Journal: Acta cardiologica 20030601

Title: [Effect of adenosine A1 receptor antagonist on learning and memory and analysis of its mechanism].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20030601

Title: Species comparison of adenosine A1 receptors in isolated mammalian atrial and ventricular myocardium.

Journal: Life sciences 20030509

Title: Adenosine receptors mediate glutamate-evoked arteriolar dilation in the rat cerebral cortex.

Journal: American journal of physiology. Heart and circulatory physiology 20030501

Title: Adenosine A1 receptor activation reduces myocardial reperfusion effects on intrinsic cardiac nervous system.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030501

Title: Adenosine A2A receptor-mediated facilitation of noradrenaline release involves protein kinase C activation and attenuation of presynaptic inhibitory receptor-mediated effects in the rat vas deferens.

Journal: Journal of neurochemistry 20030501

Title: Control of glutamatergic neurotransmission in the rat spinal dorsal horn by the nucleoside transporter ENT1.

Journal: The Journal of physiology 20030415

Title: Dialysis delivery of an adenosine A1 receptor agonist to the pontine reticular formation decreases acetylcholine release and increases anesthesia recovery time.

Journal: Anesthesiology 20030401

Title: Opposing facilitatory and inhibitory modulation of glutamate release elicited by cAMP production in cerebrocortical nerve terminals (synaptosomes).

Journal: Neuropharmacology 20030401

Title: Stimulatory effect of paeoniflorin on adenosine release to increase the glucose uptake into white adipocytes of Wistar rat.

Journal: Planta medica 20030401

Title: A2A and A3 receptors mediate the adenosine-induced relaxation in spontaneously active possum duodenum in vitro.

Journal: British journal of pharmacology 20030401

Title: Adenosine type 1 (A1) receptors mediate protection against myocardial infarction produced by chronic, intermittent ingestion of ethanol in dogs.

Journal: International journal of cardiology 20030401

Title: Extracellular ATP-induced calcium channel inhibition mediated by P1/P2Y purinoceptors in hamster submandibular ganglion neurons.

Journal: British journal of pharmacology 20030401

Title: Involvement of Rho-kinase in P2Y-receptor-mediated contraction of renal glomeruli.

Journal: Biochemical and biophysical research communications 20030321

Title: Adenosine promotes neuronal recovery from reactive oxygen species induced lesion in rat hippocampal slices.

Journal: Neuroscience letters 20030320

Title: The volatile anesthetic isoflurane suppresses spontaneous calcium oscillations in vitro in rat hippocampal neurons by activation of adenosine A1 receptors.

Journal: Neuroscience letters 20030306

Title: Adenosine inhibits N-type calcium channels at the rat neuromuscular junction.

Journal: Clinical and experimental pharmacology & physiology 20030301

Title: Adenosine A1 receptor-mediated presynaptic inhibition of GABAergic transmission in immature rat hippocampal CA1 neurons.

Journal: Journal of neurophysiology 20030301

Title: Responsiveness of renal glomeruli to adenosine in streptozotocin-induced diabetic rats dependent on hyperglycaemia level.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030301

Title: Differential allosteric modulation by amiloride analogues of agonist and antagonist binding at A(1) and A(3) adenosine receptors.

Journal: Biochemical pharmacology 20030215

Title: Pharmacological analysis of calcium responses mediated by the human A3 adenosine receptor in monocyte-derived dendritic cells and recombinant cells.

Journal: Molecular pharmacology 20030201

Title: Protein phosphatases mediate depotentiation induced by high-intensity theta-burst stimulation.

Journal: Journal of neurophysiology 20030201

Title: Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.

Journal: European journal of pharmacology 20030124

Title: Adenosine A1 receptors regulate the response of the mouse circadian clock to light.

Journal: Brain research 20030117

Title: Does nitric oxide allow endothelial cells to sense hypoxia and mediate hypoxic vasodilatation? In vivo and in vitro studies.

Journal: The Journal of physiology 20030115

Title: P2Y(1) receptor activation inhibits NMDA receptor-channels in layer V pyramidal neurons of the rat prefrontal and parietal cortex.

Journal: Neurochemistry international 20030101

Title: Adenosine A1 receptor blockade reverses experimental postoperative ileus in rat colon.

Journal: European journal of pharmacology 20030101

Title: Adenosine receptor subtypes mediating coronary vasodilation in rat hearts.

Journal: Journal of cardiovascular pharmacology 20030101

Title: Activity-dependent release of adenosine contributes to short-term depression at CA3-CA1 synapses in rat hippocampus.

Journal: Journal of neurophysiology 20030101

Title: Presynaptic inhibition of synaptic transmission by adenosine in rat subthalamic nucleus in vitro.

Journal: Neuroscience 20030101

Title: The roles of nitric oxide in dilating proximal and terminal arterioles of skeletal muscle during systemic hypoxia.

Journal: Journal of vascular research 20030101

Title: Cross-talk among noradrenaline, adenosine and protein kinase C in the mechanisms of ischemic preconditioning in rabbits.

Journal: Journal of cardiovascular pharmacology 20030101

Title: Adenosine suppresses the response of neurons to gaba in the superficial laminae of the rat spinal dorsal horn.

Journal: Neuroscience 20030101

Title: Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons.

Journal: Restorative neurology and neuroscience 20030101

Title: Purinergic P2 receptors trigger adenosine release leading to adenosine A2A receptor activation and facilitation of long-term potentiation in rat hippocampal slices.

Journal: Neuroscience 20030101

Title: Depression of fast excitatory synaptic transmission in large aspiny neurons of the neostriatum after transient forebrain ischemia.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021215

Title: Broad spectrum anticonvulsant activity of BW534U87: possible role of an adenosine-dependent mechanism.

Journal: Pharmacology, biochemistry, and behavior 20021201

Title: Basolateral and apical A1 adenosine receptors mediate sodium transport in cultured renal epithelial (A6) cells.

Journal: American journal of physiology. Renal physiology 20021201

Title: Microinjection of an adenosine A1 agonist into the medial pontine reticular formation increases tail flick latency to thermal stimulation.

Journal: Anesthesiology 20021201

Title: Preconditioning: myocardial function and energetics during coronary hypoperfusion and reperfusion.

Journal: The Annals of thoracic surgery 20021201

Title: Synthesis and evaluation of no-carrier-added 8-cyclopentyl-3-(3-[(18)F]fluoropropyl)-1-propylxanthine ([(18)F]CPFPX): a potent and selective A(1)-adenosine receptor antagonist for in vivo imaging.

Journal: Journal of medicinal chemistry 20021107

Title: New irreversible adenosine A(1) antagonists based on FSCPX.

Journal: Bioorganic & medicinal chemistry letters 20021104

Title: Transducing system operated by adenosine A(2A) receptors to facilitate acetylcholine release in the rat hippocampus.

Journal: European journal of pharmacology 20021101

Title: Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists.

Journal: Journal of medicinal chemistry 20021024

Title: Characterization of the cAMP binding site of purified S-adenosyl-homocysteine hydrolase from bovine kidney.

Journal: Biochemical pharmacology 20021015

Title: Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology.

Journal: Brain research 20021004

Title: Actions of specific adenosine receptor A1 and A2 agonists and antagonists in recovery of phrenic motor output following upper cervical spinal cord injury in adult rats.

Journal: Clinical and experimental pharmacology & physiology 20021001

Title: Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.

Journal: British journal of pharmacology 20021001

Title: Lignans isolated from valerian: identification and characterization of a new olivil derivative with partial agonistic activity at A(1) adenosine receptors.

Journal: Journal of natural products 20021001

Title: Presynaptic adenosine A1 receptors regulate retinohypothalamic neurotransmission in the hamster suprachiasmatic nucleus.

Journal: Journal of neurobiology 20020905

Title: Glucose-induced islet blood flow increase in rats: interaction between nervous and metabolic mediators.

Journal: American journal of physiology. Endocrinology and metabolism 20020901

Title: Mouse cerebellar adenosine-glutamate interactions and modulation of ethanol-induced motor incoordination.

Journal: Alcoholism, clinical and experimental research 20020901

Title: Autocrine activation of adenosine A1 receptors blocks D1A but not D1B dopamine receptor desensitization.

Journal: Journal of neurochemistry 20020901

Title: Effects of A(1) and A(2A) adenosine receptor ligands in mouse acute models of pain.

Journal: Neuroscience letters 20020816

Title: Differential effects of caffeine on dopamine and acetylcholine transmission in brain areas of drug-naive and caffeine-pretreated rats.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020801

Title: Relaxation of the mouse isolated aorta and carotid artery in response to adenosine analogues in genetically-modified mice lacking the adenosine A(2A) receptor.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020801

Title: Adenosine A1 receptor down-regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats.

Journal: Journal of neurochemistry 20020801

Title: Naturally occurring cembranes from an Australian sarcophyton species.

Journal: Journal of natural products 20020801

Title: Characterization of adenosine receptors mediating the vasodilator effects of adenosine receptor agonists in the microvasculature of the hamster cheek pouch in vivo.

Journal: Autonomic & autacoid pharmacology 20020801

Title: Coronary function and adenosine receptor-mediated responses in ischemic-reperfused mouse heart.

Journal: Cardiovascular research 20020701

Title: Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.

Journal: Molecular pharmacology 20020701

Title: Adenosine and purine nucleosides protect rat primary astrocytes from peroxynitrite-potentiated, glucose deprivation-induced death: preservation of intracellular ATP level.

Journal: Experimental neurology 20020701

Title: Mechanisms of desflurane-induced preconditioning in isolated human right atria in vitro.

Journal: Anesthesiology 20020701

Title: Protein kinase C isoforms and A1 adenosine receptors in porcine coronary smooth muscle cells.

Journal: Vascular pharmacology 20020701

Title: Role of adenine nucleotides in insulin secretion from MIN6 pseudoislets.

Journal: Molecular and cellular endocrinology 20020614

Title: Adenosine A1 receptor agonists inhibit trigeminovascular nociceptive transmission.

Journal: Brain : a journal of neurology 20020601

Title: Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes.

Journal: British journal of pharmacology 20020601

Title: Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.

Journal: The American journal of pathology 20020601

Title: 3-isobutyl-1-methylxanthine (IBMX) sensitizes cardiac myocytes to anoxia.

Journal: Biochemical pharmacology 20020601

Title: Effect of purinergic agonists and antagonists on insulin secretion from INS-1 cells (insulinoma cell line) and rat pancreatic islets.

Journal: Canadian journal of physiology and pharmacology 20020601

Title: Role of adenosine receptors in spinal G-protein activation after peripheral nerve injury.

Journal: Anesthesiology 20020601

Title: Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.

Journal: Journal of medicinal chemistry 20020523

Title: Cisplatin up-regulates the adenosine A(1) receptor in the rat kidney.

Journal: European journal of pharmacology 20020510

Title: Interaction of angiotensin II and adenosine A1 and A2A receptor ligands on the writhing test in mice.

Journal: Pharmacology, biochemistry, and behavior 20020501

Title: Neuroprotective effects of hyperthermic preconditioning on infarcted volume after middle cerebral artery occlusion in rats: role of adenosine receptors.

Journal: Critical care medicine 20020501

Title: Spinal noradrenergic activation mediates allodynia reduction from an allosteric adenosine modulator in a rat model of neuropathic pain.

Journal: Pain 20020501

Title: Adenosine inhibits calcium channel currents via A1 receptors on salamander retinal ganglion cells in a mini-slice preparation.

Journal: Journal of neurochemistry 20020501

Title: Study of an adenosine A1 receptor agonist on trigeminally evoked dural blood vessel dilation in the anaesthetized rat.

Journal: Cephalalgia : an international journal of headache 20020501

Title: 5'-Deoxy congeners of 9-(3-amido-3-deoxy-beta-D-xylofuranosyl)-N(6)-cyclopentyladenine: new adenosine A(1) receptor antagonists and inverse agonists.

Journal: Journal of medicinal chemistry 20020425

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Adenosine acting on A1 receptors protects NO-triggered rebound potentiation and LTP in rat hippocampal slices.

Journal: Journal of neurophysiology 20020401

Title: Adenosine A(2A) receptors mediate hypoxic inhibition of fetal breathing in sheep.

Journal: American journal of obstetrics and gynecology 20020401

Title: The putative roles of adenosine in insulin- and exercise-mediated regulation of glucose transport and glycogen metabolism in skeletal muscle.

Journal: Canadian journal of applied physiology = Revue canadienne de physiologie appliquee 20020401

Title: 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20020328

Title: PDE7A is expressed in human B-lymphocytes and is up-regulated by elevation of intracellular cAMP.

Journal: Cellular signalling 20020301

Title: Blockade of adenosine A1 receptors in the posterior cingulate cortex facilitates memory in rats.

Journal: European journal of pharmacology 20020222

Title: Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020215

Title: Phasic and tonic attenuation of EPSPs by inward rectifier K+ channels in rat hippocampal pyramidal cells.

Journal: The Journal of physiology 20020215

Title: Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists.

Journal: Cellular signalling 20020201

Title: A phase I randomized, multicenter trial of CPX in adult subjects with mild cystic fibrosis.

Journal: Pediatric pulmonology 20020201

Title: Use of nasal potential difference and sweat chloride as outcome measures in multicenter clinical trials in subjects with cystic fibrosis.

Journal: Pediatric pulmonology 20020201

Title: Pharmacological protection of synaptic function, spatial learning, and memory from transient hypoxia in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20020201

Title: Apparent activation of cardiovascular A1 adenosine receptors by A3 agonists.

Journal: American journal of physiology. Heart and circulatory physiology 20020201

Title: Rapid tolerance to focal cerebral ischemia in rats is attenuated by adenosine A1 receptor antagonist.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020201

Title: A(2B) adenosine receptors stimulate growth of porcine and rat arterial endothelial cells.

Journal: Hypertension (Dallas, Tex. : 1979) 20020201

Title: Effects of A(3) adenosine receptor activation and gene knock-out in ischemic-reperfused mouse heart.

Journal: Cardiovascular research 20020101

Title: Intrathecal adenosine following spinal nerve ligation in rat: short residence time in cerebrospinal fluid and no change in A(1) receptor binding.

Journal: Anesthesiology 20020101

Title: Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.

Journal: Neuroscience 20020101

Title: Lipopolysaccharide binds to and activates A(1) adenosine receptors on human pulmonary artery endothelial cells.

Journal: Journal of endotoxin research 20020101

Title: Adenosine A1 receptors control dopamine D1-dependent [(3)H]GABA release in slices of substantia nigra pars reticulata and motor behavior in the rat.

Journal: Neuroscience 20020101

Title: Molecular modeling the human A1 adenosine receptor and study of the mechanisms of its selective ligand binding.

Journal: Doklady. Biochemistry and biophysics 20020101

Title: Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum.

Journal: BMC neuroscience 20020101

Title: Mechanisms of delayed preconditioning with A1 adenosine receptor activation in porcine coronary smooth muscle cells.

Journal: Polish journal of pharmacology 20020101

Title: Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine.

Journal: American journal of physiology. Cell physiology 20011201

Title: Adenosine modulates Mg(2+) uptake in distal convoluted tubule cells via A(1) and A(2) purinoceptors.

Journal: American journal of physiology. Renal physiology 20011201

Title: Antagonism of adenosine A(1) receptors in the NTS does not affect the chemoreflex in awake rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011201

Title: Distinct myoprotective roles of cardiac sarcolemmal and mitochondrial KATP channels during metabolic inhibition and recovery.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011201

Title: Adenosine inhibits excitatory transmission to substantia gelatinosa neurons of the adult rat spinal cord through the activation of presynaptic A(1) adenosine receptor.

Journal: Pain 20011201

Title: Depression of excitatory cortico-nucleus accumbens synaptic transmission in rat brain slices by dopamine, but not adenosine, depends upon intracortical mechanisms.

Journal: Experimental brain research 20011201

Title: Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidil.

Journal: The Journal of investigative dermatology 20011201

Title: Solubilisation and immunoprecipitation of rat striatal adenosine A(2A) receptors.

Journal: European journal of pharmacology 20011116

Title: Acute and chronic caffeine administration differentially alters striatal gene expression in wild-type and adenosine A(2A) receptor-deficient mice.

Journal: Synapse (New York, N.Y.) 20011101

Title: Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists.

Journal: American journal of physiology. Cell physiology 20011101

Title: Modulation of N-type Ca2+ currents by A1-adenosine receptor activation in male rat pelvic ganglion neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20011101

Title: Activation of synaptic NMDA receptors by action potential-dependent release of transmitter during hypoxia impairs recovery of synaptic transmission on reoxygenation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011101

Title: Mechanism of intracellular calcium ([Ca2+]i) inhibition of lipolysis in human adipocytes.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101

Title: Effect of adenosine receptor blockade on pial arteriolar dilation during sciatic nerve stimulation.

Journal: American journal of physiology. Heart and circulatory physiology 20011101

Title: Oxygen delivery and oxygen consumption in rat hindlimb during systemic hypoxia: role of adenosine.

Journal: The Journal of physiology 20011101

Title: Pharmacological and biochemical characterization of adenosine receptors in the human malignant melanoma A375 cell line.

Journal: British journal of pharmacology 20011101

Title: A novel analgesic compound OT-7100 attenuates nociceptive responses in animal models of inflammatory and neuropathic hyperalgesia: a possible involvement of adenosinergic anti-nociception.

Journal: Japanese journal of pharmacology 20011101

Title: Neuronal mechanisms of the anoxia-induced network oscillations in the rat hippocampus in vitro.

Journal: The Journal of physiology 20011015

Title: Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.

Journal: British journal of pharmacology 20011001

Title: Role of adenosine in renal protection induced by a brief episode of ischemic preconditioning in rats.

Journal: Japanese journal of pharmacology 20011001

Title: Different activation mechanisms of cystic fibrosis transmembrane conductance regulator expressed in Xenopus laevis oocytes.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011001

Title: Smooth muscle does not have a common P2x receptor phenotype: expression, ontogeny and function of P2x1 receptors in mouse ileum, bladder and reproductive systems.

Journal: Autonomic neuroscience : basic & clinical 20010917

Title: Effects of angiotensin III and angiotensin IV on pentylenetetrazol seizure susceptibility (threshold and kindling): interaction with adenosine A(1) receptors.

Journal: Brain research bulletin 20010915

Title: Amp 579 reduces contracture and limits infarction in rabbit heart by activating adenosine A2 receptors.

Journal: Journal of cardiovascular pharmacology 20010901

Title: Adenosine linking reduced O2 to arteriolar NO release in intestine is not formed from extracellular ATP.

Journal: American journal of physiology. Heart and circulatory physiology 20010901

Title: Adenosine-mediated inhibition of striatal GABAergic synaptic transmission during in vitro ischaemia.

Journal: Brain : a journal of neurology 20010901

Title: The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells.

Journal: British journal of pharmacology 20010901

Title: Pharmacological and biochemical characterization of A3 adenosine receptors in Jurkat T cells.

Journal: British journal of pharmacology 20010901

Title: Inhibitory effect of ischemic preconditioning on leukocyte participation in retinal ischemia-reperfusion injury.

Journal: Investigative ophthalmology & visual science 20010901

Title: Systemic adenosine given after ischemia protects renal function via A(2a) adenosine receptor activation.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20010901

Title: Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.

Journal: British journal of pharmacology 20010901

Title: Adenosine inhibits glutamate exocytosis largely without interfering with Ca2+ influx in rat cerebrocortical synaptosomes.

Journal: Neuroscience letters 20010831

Title: Adenosine A(1) receptor agonism in the immature rat brain and heart.

Journal: European journal of pharmacology 20010831

Title: Adenosine A1 receptors reduce release from excitatory but not inhibitory synaptic inputs onto lateral horn neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815

Title: Adenosine receptor antagonists cancelled the ischemic tolerance phenomenon in gerbil.

Journal: Brain research 20010810

Title: Adenosine A3 agonist cardioprotection in isolated rat and rabbit hearts is blocked by the A1 antagonist DPCPX.

Journal: American journal of physiology. Heart and circulatory physiology 20010801

Title: Isoflurane-induced protection against myocardial stunning is independent of adenosine 1 (A(1)) receptor in isolated rat heart.

Journal: British journal of anaesthesia 20010801

Title: Allosteric adenosine modulation to reduce allodynia.

Journal: Anesthesiology 20010801

Title: Control of the proinflammatory state in cystic fibrosis lung epithelial cells by genes from the TNF-alphaR/NFkappaB pathway.

Journal: Molecular medicine (Cambridge, Mass.) 20010801

Title: AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation.

Journal: Journal of molecular neuroscience : MN 20010801

Title: Withdrawal and bidirectional cross-withdrawal responses in rats treated with adenosine agonists and morphine.

Journal: Life sciences 20010706

Title: Adenosine A(1) and A(2A) receptors modulate sleep state and breathing in fetal sheep.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010701

Title: Modulation of ethanol-induced motor incoordination by mouse striatal A(1) adenosinergic receptor.

Journal: Brain research bulletin 20010701

Title: Involvement of the cerebellar adenosine A(1) receptor in cannabinoid-induced motor incoordination in the acute and tolerant state in mice.

Journal: Brain research 20010629

Title: Agonist-stimulated [35S]GTPgammaS autoradiography: optimization for high sensitivity.

Journal: European journal of pharmacology 20010622

Title: Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20010619

Title: Poly(lactic acid) microspheres for the sustained release of a selective A1 receptor agonist.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20010615

Title: Adenosine A(1) receptor-mediated inhibition of protein kinase A-induced calcitonin gene-related peptide release from rat trigeminal neurons.

Journal: Molecular pharmacology 20010601

Title: Inhibition of calcium channels by opioid- and adenosine-receptor agonists in neurons of the nucleus accumbens.

Journal: British journal of pharmacology 20010601

Title: Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010515

Title: Anti-adrenergic effect of adenosine on Na(+)-Ca(2+) exchange current recorded from guinea-pig ventricular myocytes.

Journal: Cell calcium 20010501

Title: Receptor subtypes mediating adenosine-induced dilation of cerebral arterioles.

Journal: American journal of physiology. Heart and circulatory physiology 20010501

Title: Determination of amino acid residues that are accessible from the ligand binding crevice in the seventh transmembrane-spanning region of the human A(1) adenosine receptor.

Journal: Molecular pharmacology 20010501

Title: Age-dependent decrease in adenosine A1 receptor binding sites in the rat brain. Effect of cis unsaturated free fatty acids.

Journal: European journal of biochemistry 20010501

Title: Ameliorative effects of paeoniflorin, a major constituent of peony root, on adenosine A1 receptor-mediated impairment of passive avoidance performance and long-term potentiation in the hippocampus.

Journal: Biological & pharmaceutical bulletin 20010501

Title: Electrically evoked release of glutamate in rat hippocampal slices: effects of various drugs and fimbria-fornix lesions.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010501

Title: A functional role for adenosine A3 receptors: modulation of synaptic plasticity in the rat hippocampus.

Journal: Neuroscience letters 20010413

Title: Dissociation between synaptic depression and block of long-term depression induced by raising the temperature in rat hippocampal slices.

Journal: Synapse (New York, N.Y.) 20010401

Title: Effect of an adenosine A(1) receptor agonist and a novel pyrimidoindole on membrane properties and neurotransmitter release in rat cortical and hippocampal neurons.

Journal: Neurochemistry international 20010401

Title: A depletable pool of adenosine in area CA1 of the rat hippocampus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010401

Title: [(35)S]GTPgammaS autoradiography reveals a wide distribution of G(i/o)-linked ADP receptors in the nervous system: close similarities with the platelet P2Y(ADP) receptor.

Journal: Journal of neurochemistry 20010401

Title: 2-chloro-N(6)-cyclopentyladenosine-elicited attenuation of evoked glutamate release is not sufficient to give complete protection against pilocarpine-induced seizures in rats.

Journal: Neuropharmacology 20010401

Title: Subchronic treatment with methamphetamine and phencyclidine differentially alters the adenosine A1 and A2A receptors in the prefrontal cortex, hippocampus, and striatum of the rat.

Journal: Neurochemical research 20010401

Title: Adenosine enhances neuroexcitability by inhibiting a slow postspike afterhyperpolarization in rabbit vagal afferent neurons.

Journal: Circulation 20010306

Title: Adenosine receptor-adenylate cyclase system in the trout testis: involvement in the regulation of germ cell proliferation.

Journal: Molecular reproduction and development 20010301

Title: Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning.

Journal: Cardiovascular research 20010301

Title: Relaxation of mouse isolated aorta to adenosine and its analogues does not involve adenosine A(1), A(2) or A(3) receptors.

Journal: European journal of pharmacology 20010301

Title: Adenosine A1 receptors regulate the response of the hamster circadian clock to light.

Journal: European journal of pharmacology 20010223

Title: Regulation of p42/p44 MAPK and p38 MAPK by the adenosine A(1) receptor in DDT(1)MF-2 cells.

Journal: European journal of pharmacology 20010216

Title: Distinct modulation of evoked and spontaneous EPSCs by purinoceptors in the nucleus tractus solitarii of the rat.

Journal: The Journal of physiology 20010201

Title: Adenosine-enhanced ischemic preconditioning: adenosine receptor involvement during ischemia and reperfusion.

Journal: American journal of physiology. Heart and circulatory physiology 20010201

Title: Regulation of G protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine.

Journal: American journal of respiratory cell and molecular biology 20010201

Title: Müller cell Ca2+ waves evoked by purinergic receptor agonists in slices of rat retina.

Journal: Journal of neurophysiology 20010201

Title: A1 adenosine receptors inhibit multiple voltage-gated Ca2+ channel subtypes in acutely isolated rat basolateral amygdala neurons.

Journal: British journal of pharmacology 20010201

Title: G protein activation in rat ponto-mesencephalic nuclei is enhanced by combined treatment with a mu opioid and an adenosine A1 receptor agonist.

Journal: Sleep 20010201

Title: A(2b) receptors mediate the antimitogenic effects of adenosine in cardiac fibroblasts.

Journal: Hypertension (Dallas, Tex. : 1979) 20010201

Title: Activation of presynaptic A1-receptors by endogenous adenosine inhibits acetylcholine release in the guinea-pig ileum.

Journal: Journal of autonomic pharmacology 20010201

Title: 3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: a new class of selective A1 adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 20010201

Title: K(ATP) channel blockers selectively interact with A(1)-adenosine receptor mediated modulation of acetylcholine release in the rat hippocampus.

Journal: Brain research 20010119

Title: Adenosine A(1) and A(3) receptors mediate inhibition of synaptic transmission in rat cortical neurons.

Journal: Neuropharmacology 20010101

Title: Pharmacological treatment of the ion transport defect in cystic fibrosis.

Journal: Expert opinion on investigational drugs 20010101

Title: Adenosine A(2A) receptors mediate cardiovascular responses to hypoxia in fetal sheep.

Journal: American journal of physiology. Heart and circulatory physiology 20010101

Title: Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes.

Journal: Journal of molecular and cellular cardiology 20010101

Title: Extracellular adenosine modulates a volume-sensitive-like chloride conductance in immortalized rabbit DC1 cells.

Journal: American journal of physiology. Renal physiology 20010101

Title: Adenosine activates aromatic L-amino acid decarboxylase activity in the kidney and increases dopamine.

Journal: Journal of the American Society of Nephrology : JASN 20010101

Title: Characterization of prejunctional purinoceptors inhibiting noradrenaline release in rat mesenteric arteries.

Journal: Japanese journal of pharmacology 20010101

Title: Cardioprotective effects of adenosine A1 and A3 receptor activation during hypoxia in isolated rat cardiac myocytes.

Journal: Molecular and cellular biochemistry 20010101

Title: Reduced PO(2) and adenosine formation preserve arteriolar nitric oxide synthesis during sympathetic constriction in the rat intestine.

Journal: Journal of vascular research 20010101

Title: Adenosine preferentially suppresses serotonin2A receptor-enhanced excitatory postsynaptic currents in layer V neurons of the rat medial prefrontal cortex.

Journal: Neuroscience 20010101

Title: The sulphydryl reagent, N-ethylmaleimide, disrupts sleep and blocks A1 adenosine receptor-mediated inhibition of intracellular calcium signaling in the in vitro ventromedial preoptic nucleus.

Journal: Neuroscience 20010101

Title: Pharmacology of airway afferent nerve activity.

Journal: Respiratory research 20010101

Title: [Comparative characteristics of A1-receptor agonists as neuroprotective agents].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101

Title: The CFTR-mediated protein secretion defect: pharmacological correction.

Journal: Pflugers Archiv : European journal of physiology 20010101

Title: Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20001001

Title: Inducible nitric oxide synthase mediates delayed myocardial protection induced by activation of adenosine A(1) receptors: evidence from gene-knockout mice.

Journal: Circulation 20000822

Title: Cerebellar CB(1) receptor mediation of Delta(9)-THC-induced motor incoordination and its potentiation by ethanol and modulation by the cerebellar adenosinergic A(1) receptor in the mouse.

Journal: Brain research 20000512

Title: [(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.

Journal: Molecular pharmacology 20000501

Title: A1 adenosine receptor activation increases adipocyte leptin secretion.

Journal: Endocrinology 20000401

Title: Differential expression of renal adenosine A(1) receptors induced by acute renal failure.

Journal: Biochemical pharmacology 20000315

Title: N-cycloalkyl derivatives of adenosine and 1-deazaadenosine as agonists and partial agonists of the A(1) adenosine receptor.

Journal: Journal of medicinal chemistry 20000127

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Tags:102146-07-6 Molecular Formula|102146-07-6 MDL|102146-07-6 SMILES|102146-07-6 1H-Purine-2,6-dione, 8-cyclopentyl-3,9-dihydro-1,3-dipropyl-