Home Bromides 1022-79-3
1022-79-3,MFCD00047496
Catalog No.:AA0006T7

1022-79-3 | 5-Bromo-2'-deoxycytidine

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1g
95%
in stock  
$54.00   $38.00
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5g
99%
in stock  
$80.00   $56.00
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25g
99%
in stock  
$395.00   $277.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0006T7
Chemical Name:
5-Bromo-2'-deoxycytidine
CAS Number:
1022-79-3
Molecular Formula:
C9H12BrN3O4
Molecular Weight:
306.1133
MDL Number:
MFCD00047496
SMILES:
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(Br)c(nc1=O)N
Properties
Computed Properties
 
Complexity:
398  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
-0.9  

Literature

Title: Synthesis, molecular conformation and activity against herpes simplex virus of (E)-5-(2-bromovinyl)-2'-deoxycytidine analogs.

Journal: Nucleosides, nucleotides & nucleic acids 20120401

Title: Effects of the genotoxic agent 5-bromo-2'-deoxyuridine with or without pre-pubertal gonadectomy on brain monoamines and their metabolites in female rats.

Journal: Brain research bulletin 20110530

Title: Mutational specificities of brominated DNA adducts catalyzed by human DNA polymerases.

Journal: Journal of molecular biology 20110311

Title: Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation.

Journal: Cell death & disease 20100901

Title: Reaction of 2'-deoxycytidine with peroxynitrite in the presence of ammonium bromide.

Journal: Bioorganic & medicinal chemistry 20080501

Title: Hypoxia-driven proliferation of embryonic neural stem/progenitor cells--role of hypoxia-inducible transcription factor-1alpha.

Journal: The FEBS journal 20080401

Title: Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.

Journal: Journal of medicinal chemistry 20061019

Title: Inhibition of severe acute respiratory syndrome-associated coronavirus (SARSCoV) by calpain inhibitors and beta-D-N4-hydroxycytidine.

Journal: Antiviral chemistry & chemotherapy 20040101

Title: Identification and quantification of mutagenic halogenated cytosines by gas chromatography, fast atom bombardment, and electrospray ionization tandem mass spectrometry.

Journal: Analytical biochemistry 20030615

Title: A novel concept of glomeruloid body formation in experimental cerebral metastases.

Journal: Journal of neuropathology and experimental neurology 20030601

Title: Relation of distal nephron changes to proximal tubular damage in uranyl acetate-induced acute renal failure in rats.

Journal: American journal of nephrology 20020101

Title: Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation.

Journal: The Journal of biological chemistry 20010316

Title: Synthesis and antiviral activity of phosphonoacetic and phosphonoformic acid esters of 5-bromo-2'-deoxyuridine and related pyrimidine nucleosides and acyclonucleosides.

Journal: Journal of medicinal chemistry 19890201

Title: Synthesis and antiviral properties of (E)-5-(2-bromovinyl)-2'-deoxycytidine-related compounds.

Journal: Journal of medicinal chemistry 19880101

Title: (E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19790601

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Tags:1022-79-3 Molecular Formula|1022-79-3 MDL|1022-79-3 SMILES|1022-79-3 5-Bromo-2'-deoxycytidine