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1026016-83-0,MFCD08461052
Catalog No.:AA0007ST

1026016-83-0 | Tetrabenazine (+)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25mg
97%
in stock  
$124.00   $87.00
- +
100mg
97%
in stock  
$251.00   $176.00
- +
1g
97%
in stock  
$600.00   $420.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0007ST
Chemical Name:
Tetrabenazine (+)-
CAS Number:
1026016-83-0
Molecular Formula:
C19H27NO3
Molecular Weight:
317.4226
MDL Number:
MFCD08461052
SMILES:
COc1cc2c(cc1OC)CCN1[C@@H]2CC(=O)[C@@H](C1)CC(C)C
Properties
Computed Properties
 
Complexity:
425  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
2.9  

Literature

Title: Tetrabenazine for the treatment of chorea and other hyperkinetic movement disorders.

Journal: Expert review of neurotherapeutics 20111101

Title: Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors.

Journal: European journal of medicinal chemistry 20110501

Title: Quadriparesis and dysarthria due to tetrabenazine therapy in a child with rheumatic chorea.

Journal: Indian journal of pharmacology 20110101

Title: Dantrolene is neuroprotective in Huntington's disease transgenic mouse model.

Journal: Molecular neurodegeneration 20110101

Title: Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders.

Journal: The American journal of geriatric pharmacotherapy 20100801

Title: Calcium signaling and neurodegeneration.

Journal: Acta naturae 20100401

Title: ELBARA II, an L-band radiometer system for soil moisture research.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Tetrabenazine in the treatment of Huntington's disease.

Journal: Neuropsychiatric disease and treatment 20071001

Title: Podurgiel SJ et al. The MAO-B inhibitor deprenyl reduces the oral tremor and the dopamine depletion induced by the VMAT-2 inhibitor tetrabenazine. Behav Brain Res. 2016 Feb 1;298(Pt B):188-91.

Title: Peter D et al. Chimeric vesicular monoamine transporters identify structural domains that influence substrate affinity and sensitivity to tetrabenazine. J Biol Chem. 1996 Feb 9;271(6):2979-86.

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