Title: Peripheral ammonia as a mediator of methamphetamine neurotoxicity.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120919
Title: Cocaine-taking and cocaine-seeking behaviors in rats remain stable after systemic administration of GYKI 52466: a non-competitive AMPA receptor antagonist.
Journal: Neuroscience letters 20120206
Title: Mechanism of inhibition of the GluA2 AMPA receptor channel opening: consequences of adding an N-3 methylcarbamoyl group to the diazepine ring of 2,3-benzodiazepine derivatives.
Journal: Biochemistry 20110823
Title: Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice.
Journal: The Journal of clinical investigation 20110401
Title: The role of NMDA and AMPA/Kainate receptors in the consolidation of catalepsy sensitization.
Journal: Behavioural brain research 20110317
Title: Glutamate receptors in laryngeal cancer cells.
Journal: Anticancer research 20110201
Title: Gender specific influence of endogenous glutamate release on stress-induced fear in rats.
Journal: Endocrine regulations 20110101
Title: Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm.
Journal: The international journal of neuropsychopharmacology 20101001
Title: Involvement of non-NMDA receptors in central mediation of chemoreflexes in the shorthorn sculpin, Myoxocephalus scorpius.
Journal: Respiratory physiology & neurobiology 20100731
Title: Postnatal change of GluR5 kainate receptor expression in the substantia gelatinosa neuron of the trigeminal subnucleus caudalis in mice.
Journal: Brain research 20100730
Title: Stimulation of lateral hypothalamic AMPA receptors may induce feeding in rats.
Journal: Brain research 20100730
Title: Selective excitatory actions of DNQX and CNQX in rat thalamic neurons.
Journal: Journal of neurophysiology 20100401
Title: GYKI-52466: a potential therapeutic agent for glutamate-mediated excitotoxic injury in Cerebral Palsy.
Journal: Medical hypotheses 20100301
Title: Treatment of early and late kainic acid-induced status epilepticus with the noncompetitive AMPA receptor antagonist GYKI 52466.
Journal: Epilepsia 20100101
Title: Glutamatergic mechanisms for speed control and network operation in the rodent locomotor CpG.
Journal: Frontiers in neural circuits 20100101
Title: Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20091101
Title: Effects of GYKI 52466 on early vasospasm in rats.
Journal: Central European neurosurgery 20091101
Title: Regulation of glutamate transport in developing rat oligodendrocytes.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090617
Title: Modification of ionotropic glutamate receptor-mediated processes in the rat hippocampus following repeated, brief seizures.
Journal: Neuroscience 20090303
Title: Solution-phase parallel synthesis and evaluation of anticonvulsant activity of N-substituted-3,4-dihydroisoquinoline-2(1H)-carboxamides.
Journal: European journal of medicinal chemistry 20090301
Title: GluK2-mediated excitability within the superficial layers of the entorhinal cortex.
Journal: PloS one 20090101
Title: Pharmacological characterization, localization, and regulation of ionotropic glutamate receptors in skate horizontal cells.
Journal: Visual neuroscience 20090101
Title: CNQX and AMPA inhibit electrical synaptic transmission: a potential interaction between electrical and glutamatergic synapses.
Journal: Brain research 20080904
Title: AMPA receptor-dependent H2O2 generation in striatal medium spiny neurons but not dopamine axons: one source of a retrograde signal that can inhibit dopamine release.
Journal: Journal of neurophysiology 20080901
Title: High-frequency organization and synchrony of activity in the purkinje cell layer of the cerebellum.
Journal: Neuron 20080612
Title: Antagonism of AMPA receptors produces anxiolytic-like behavior in rodents: effects of GYKI 52466 and its novel analogues.
Journal: Psychopharmacology 20080601
Title: Synthesis and anticonvulsant evaluation of N-substituted isoquinoline AMPA receptor antagonists.
Journal: Bioorganic & medicinal chemistry 20080301
Title: Structure-activity study of 2,3-benzodiazepin-4-ones noncompetitive AMPAR antagonists: identification of the 1-(4-amino-3-methylphenyl)-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4-one as neuroprotective agent.
Journal: Bioorganic & medicinal chemistry 20080301
Title: Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test.
Journal: Neuropharmacology 20080301
Title: [Involvement of the amygdala on place aversion induced by naloxone in single-dose morphine-treated rats].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080301
Title: The role of hippocampal GluR1 and GluR2 receptors in manic-like behavior.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080102
Title: Blockade of AMPA-receptors attenuates 4-aminopyridine seizures, decreases the activation of inhibitory neurons but is ineffective against seizure-related astrocytic swelling.
Journal: Epilepsy research 20080101
Title: Spontaneous release from mossy fiber terminals inhibits Ni2+-sensitive T-type Ca2+ channels of CA3 pyramidal neurons in the rat organotypic hippocampal slice.
Journal: Hippocampus 20080101
Title: Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in complete Freund's adjuvant-induced inflammatory pain.
Journal: Molecular pain 20080101
Title: AMPA antagonists inhibit the extracellular signal regulated kinase pathway and suppress lung cancer growth.
Journal: Cancer biology & therapy 20071201
Title: AMPA receptor antagonists reverse effects of extended habit training on signaled food approach responding in rats.
Journal: Psychopharmacology 20071101
Title: Activation of extrasynaptic NMDA receptors induces a PKC-dependent switch in AMPA receptor subtypes in mouse cerebellar stellate cells.
Journal: The Journal of physiology 20070901
Title: Benzodiazepine-induced hippocampal CA1 neuron alpha-amino-3-hydroxy-5-methylisoxasole-4-propionic acid (AMPA) receptor plasticity linked to severity of withdrawal anxiety: differential role of voltage-gated calcium channels and N-methyl-D-aspartic acid receptors.
Journal: Behavioural pharmacology 20070901
Title: Presynaptic AMPA and kainate receptors increase the size of GABAergic terminals and enhance GABA release.
Journal: Neuropharmacology 20070601
Title: Differential contribution of kainate receptors to excitatory postsynaptic currents in superficial layer neurons of the rat medial entorhinal cortex.
Journal: Neuroscience 20070525
Title: Effects of 2,3-benzodiazepine AMPA receptor antagonists on dopamine turnover in the striatum of rats with experimental parkinsonism.
Journal: Brain research bulletin 20070315
Title: Acute effects of AMPA-type glutamate receptor antagonists on intermale social behavior in two mouse lines bidirectionally selected for offensive aggression.
Journal: Pharmacology, biochemistry, and behavior 20070101
Title: Cyclothiazide prolongs low [Mg2+]-induced seizure-like events.
Journal: Journal of neurophysiology 20061201
Title: Novel potent anticonvulsant agent containing a tetrahydroisoquinoline skeleton.
Journal: Journal of medicinal chemistry 20060907
Title: Purine release from spinal cord microglia after elevation of calcium by glutamate.
Journal: Molecular pharmacology 20060901
Title: Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060705
Title: 3D pharmacophore models for 1,2,3,4-tetrahydroisoquinoline derivatives acting as anticonvulsant agents.
Journal: Archiv der Pharmazie 20060701
Title: Neural overexcitation and implication of NMDA and AMPA receptors in a mouse model of temporal lobe epilepsy implying zinc chelation.
Journal: Epilepsia 20060501
Title: Effect of glutamate receptor antagonists and antirheumatic drugs on proliferation of synoviocytes in vitro.
Journal: European journal of pharmacology 20060327
Title: Methamphetamine-induced spectrin proteolysis in the rat striatum.
Journal: Journal of neurochemistry 20060301
Title: Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060301
Title: Limited regulation of somatodendritic dopamine release by voltage-sensitive Ca channels contrasted with strong regulation of axonal dopamine release.
Journal: Journal of neurochemistry 20060201
Title: Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125
Title: New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20060101
Title: Localization and function of pre- and postsynaptic kainate receptors in the rat globus pallidus.
Journal: The European journal of neuroscience 20060101
Title: C-type natriuretic peptide modulates glutamate receptors on cultured rat retinal amacrine cells.
Journal: Neuroscience 20060101
Title: A comparison of release kinetics and glutamate receptor properties in shaping rod-cone differences in EPSC kinetics in the salamander retina.
Journal: The Journal of physiology 20051215
Title: Activation of c-Jun NH2-terminal kinase 3 is mediated by the GluR6.PSD-95.MLK3 signaling module following cerebral ischemia in rat hippocampus.
Journal: Brain research 20051102
Title: The effects of AMPA receptor antagonists in models of stroke and neurodegeneration.
Journal: European journal of pharmacology 20050905
Title: Novel alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor antagonists of 2,3-benzodiazepine type: chemical synthesis, in vitro characterization, and in vivo prevention of acute neurodegeneration.
Journal: Journal of medicinal chemistry 20050714
Title: Effect of glutamate receptor antagonists on place aversion induced by naloxone in single-dose morphine-treated rats.
Journal: British journal of pharmacology 20050701
Title: A method for producing overactive bladder in the rat and investigation of the effects of GABAergic receptor agonists and glutamatergic receptor antagonists on the cystometrogram.
Journal: The Journal of urology 20050501
Title: C-terminal truncation affects kinetic properties of GluR1 receptors.
Journal: Molecular and cellular neurosciences 20050501
Title: Role of NMDA and AMPA glutamate receptors in the induction and the expression of dopamine-mediated sensitization in 6-hydroxydopamine-lesioned rats.
Journal: Synapse (New York, N.Y.) 20050401
Title: Malignant glioma-induced neuronal cell death in an organotypic glioma invasion model. Technical note.
Journal: Journal of neurosurgery 20050401
Title: AMPA/kainate receptor-mediated downregulation of GABAergic synaptic transmission by calcineurin after seizures in the developing rat brain.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050330
Title: Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050209
Title: Glutamate receptor antagonists and benzodiazepine inhibit the progression of granule cell dispersion in a mouse model of mesial temporal lobe epilepsy.
Journal: Epilepsia 20050201
Title: p21(WAF1/Cip1) is not involved in kainic acid-induced apoptosis in murine cerebellar granule cells.
Journal: Brain research 20041231
Title: Excitotoxic and post-ischemic neurodegeneration: Involvement of transglutaminases.
Journal: Amino acids 20041201
Title: Transient Ca2+-permeable AMPA receptors in postnatal rat primary auditory neurons.
Journal: The European journal of neuroscience 20041201
Title: Effect of two noncompetitive AMPA receptor antagonists GYKI 52466 and GYKI 53405 on vigilance, behavior and spike-wave discharges in a genetic rat model of absence epilepsy.
Journal: Brain research 20040522
Title: Synthesis and anticonvulsant activity of N-3 substituted 2,3-benzodiazepines.
Journal: Farmaco (Societa chimica italiana : 1989) 20040501
Title: Omeprazole and talampanel as two examples of retrometabolic drug design.
Journal: Die Pharmazie 20040501
Title: Immunocytochemical localization and expression of heme oxygenase-1 in primary astroglial cell cultures during differentiation: effect of glutamate.
Journal: Biochemical and biophysical research communications 20040305
Title: Activation of ionotropic glutamate receptors on peripheral axons of primary motoneurons mediates transmitter release at the zebrafish NMJ.
Journal: Journal of neurophysiology 20040201
Title: Synthesis and anticonvulsant properties of tetrahydroisoquinoline derivatives.
Journal: Farmaco (Societa chimica italiana : 1989) 20040101
Title: Neurotransmitter actions on transient amacrine and ganglion cells of the turtle retina.
Journal: Visual neuroscience 20040101
Title: Glutamate receptor subtypes in human retinal horizontal cells.
Journal: Visual neuroscience 20040101
Title: Administration of a non-NMDA antagonist, GYKI 52466, increases excitotoxic Purkinje cell degeneration caused by ibogaine.
Journal: Neuroscience 20040101
Title: Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1.
Journal: Journal of neurochemistry 20031101
Title: Synthesis and evaluation of pharmacological properties of novel annelated 2,3-benzodiazepine derivatives.
Journal: Journal of medicinal chemistry 20030814
Title: Characterization of spontaneous synaptic transmission in rat medial vestibular nucleus.
Journal: Neuroreport 20030806
Title: Glutamate-induced increases in transglutaminase activity in primary cultures of astroglial cells.
Journal: Brain research 20030718
Title: Effect of glutamate receptor antagonists on suckling-induced prolactin release in rats.
Journal: Endocrine 20030701
Title: Participation of AMPA- and NMDA-type excitatory amino acid receptors in the spinal reflex transmission, in rat.
Journal: Brain research bulletin 20030415
Title: AMPA receptors on developing medial septum/diagonal band neurons are sensitive to early postnatal binge-like ethanol exposure.
Journal: Brain research. Developmental brain research 20030414
Title: Glutamate-dependent inhibition of dopamine release in striatum is mediated by a new diffusible messenger, H2O2.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030401
Title: Neuroprotective effects of GYKI 52466 on experimental spinal cord injury in rats.
Journal: Journal of neurosurgery 20030401
Title: Characterization of the mechanism of anticonvulsant activity for a selected set of putative AMPA receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20030210
Title: Discovery of a novel and highly potent noncompetitive AMPA receptor antagonist.
Journal: Journal of medicinal chemistry 20030102
Title: The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism.
Journal: Neuroscience 20030101
Title: Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats.
Journal: Brain research bulletin 20021015
Title: Novel potent AMPA/kainate receptor antagonists: synthesis and anticonvulsant activity of a series of 2-[(4-alkylsemicarbazono)-(4-amino-phenyl)methyl]-4,5-methylenedioxyphenylacetic acid alkyl esters.
Journal: Journal of medicinal chemistry 20020926
Title: Suppression by zinc of AMPA receptor-mediated synaptic transmission in the retina.
Journal: Journal of neurophysiology 20020901
Title: Comparison of spontaneous and evoked epileptiform activity in three in vitro epilepsy models.
Journal: Brain research 20020802
Title: Molsidomine potentiates the protective activity of GYKI 52466, a non-NMDA antagonist, MK-801, a non-competitive NMDA antagonist, and riluzole against electroconvulsions in mice.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020801
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: The non-competitive AMPA receptor antagonist (GYKI 52466) blocks quisqualate-induced acetylcholine release from the rat hippocampus and striatum: an in vivo microdialysis study.
Journal: Neurochemistry international 20020401
Title: Somatostatin stimulates striatal acetylcholine release by glutamatergic receptors: an in vivo microdialysis study.
Journal: Neurochemistry international 20020301
Title: A non-excitatory paradigm of glutamate toxicity.
Journal: Journal of neurophysiology 20020301
Title: Effects of phencyclidine (PCP) and MK 801 on the EEGq in the prefrontal cortex of conscious rats; antagonism by clozapine, and antagonists of AMPA-, alpha(1)- and 5-HT(2A)-receptors.
Journal: British journal of pharmacology 20020101
Title: The Neurobiology and Neuropharmacology of Alzheimer's Disease. The ASPET - Ray Fuller Symposium. New Orleans, LA, USA, April 19-20, 2002.
Journal: CNS drug reviews 20020101
Title: beta-Adrenoceptor blockade enhances the anticonvulsant effect of glutamate receptor antagonists against maximal electroshock.
Journal: European journal of pharmacology 20011116
Title: Early activation of Ca(2+)-permeable AMPA receptors reduces neurite outgrowth in embryonic chick retinal neurons.
Journal: Journal of neurobiology 20011115
Title: Modulation of excitatory synaptic transmission by GABA(C) receptor-mediated feedback in the mouse inner retina.
Journal: Journal of neurophysiology 20011101
Title: Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures.
Journal: Brain research 20011026
Title: Group I metabotropic glutamate receptors limit AMPA receptor-mediated oligodendrocyte progenitor cell death.
Journal: European journal of pharmacology 20010727
Title: In vivo pharmacology of BIIR 561 CL, a novel combined antagonist of AMPA receptors and voltage-dependent Na(+) channels.
Journal: British journal of pharmacology 20010701
Title: Ampa/kainate receptor activation mediates hypoxic oligodendrocyte death and axonal injury in cerebral white matter.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010615
Title: Comparison of anticonvulsive and acute neuroprotective activity of three 2,3-benzodiazepine compounds, GYKI 52466, GYKI 53405, and GYKI 53655.
Journal: Brain research bulletin 20010601
Title: Analysis of spontaneous EPSCs in retinal horizontal cells of the carp.
Journal: Neuroscience research 20010501
Title: GYKI 52466 has positive modulatory effects on AMPA receptors.
Journal: Brain research 20010223
Title: In vivo, the direct and seizure-induced neuronal cytotoxicity of kainate and AMPA is modified by the non-competitive antagonist, GYKI 52466.
Journal: Brain research 20010126
Title: Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse.
Journal: Neuropharmacology 20010101
Title: Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated stimulation of glutamate and GABA release in the rat striatum in vivo: a dual-label microdialysis study.
Journal: Neuroscience 20010101
Title: Na(+)-K(+)-ATPase inhibition and depolarization induce glutamate release via reverse Na(+)-dependent transport in spinal cord white matter.
Journal: Neuroscience 20010101
Title: Functionally different AMPA-type glutamate receptors in morphologically identified neurons in rat superficial superior colliculus.
Journal: Neuroscience 20010101
Title: Interaction of GYKI 52466, a selective non-competitive antagonist of AMPA/kainate receptors, with conventional antiepileptic drugs in amygdala-kindled seizures in rats.
Journal: Polish journal of pharmacology 20010101
Title: AMPA-preferring receptors mediate excitatory non-NMDA responses of primate retinal ganglion cells.
Journal: Visual neuroscience 20010101
Title: Effect of ionotropic glutamate receptors antagonists on the modifications in extracellular glutamate and aspartate levels during picrotoxin seizures: a microdialysis study in freely moving rats.
Journal: Neurochemistry international 20001001
Title: Effects of AMPA/kainate glutamate receptor antagonists on cocaine-induced convulsions and lethality in mice.
Journal: European journal of pharmacology 19991215
Title: Anticonvulsants for soman-induced seizure activity.
Journal: Journal of biomedical science 19990101
Title: The vital dye Evans blue mimics limbic seizures induced by kainate or pilocarpine.
Journal: Brain research 19970411
Title: Morphine-induced catalepsy is augmented by NMDA receptor antagonists, but is partially attenuated by an AMPA receptor antagonist.
Journal: European journal of pharmacology 19960111
Title: Some central effects of GYKI 52466, a non-competitive AMPA receptor antagonist.
Journal: Polish journal of pharmacology 19950101
Title: Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil.
Journal: British journal of pharmacology 19941201
Title: The AMPA receptor antagonist GYKI 52466 reverses the anti-cataleptic effects of the competitive NMDA receptor antagonist CGP 37849.
Journal: European journal of pharmacology 19940502
Title: The non-NMDA glutamate receptor antagonist GYKI 52466 counteracts locomotor stimulation and anticataleptic activity induced by the NMDA antagonist dizocilpine.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 19931101