Home Pyridines 103-74-2
103-74-2,MFCD00006364
Catalog No.:AA0037YI

103-74-2 | 2-Pyridineethanol

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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0037YI
Chemical Name:
2-Pyridineethanol
CAS Number:
103-74-2
Molecular Formula:
C7H9NO
Molecular Weight:
123.1525
MDL Number:
MFCD00006364
SMILES:
OCCc1ccccn1
Properties
Computed Properties
 
Complexity:
75.3  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
0.1  

Upstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1939,vol.61,p.961,963

[2]JournaloftheAmericanChemicalSociety,1946,vol.68,p.1572,1575

[3]JournaloftheAmericanChemicalSociety,1958,vol.80,p.2217,2219

[4]JournaloftheAmericanChemicalSociety,1947,vol.69,p.630,631

[5]JournaloftheAmericanChemicalSociety,1958,vol.80,p.2217,2219

[6]JournaloftheAmericanChemicalSociety,1947,vol.69,p.630,631

[7]Patent:US6258955,2001,B1,

[8]Patent:US6258955,2001,B1,

[1]Patent:US6258955,2001,B1,

[1]SyntheticCommunications,2017,vol.47,#10,p.968-974

[1]ChemischeBerichte,1889,vol.22,p.2584

[2]ChemischeBerichte,1891,vol.24,p.1620

[3]ChemischeBerichte,1907,vol.40,p.1328

[4]JustusLiebigsAnnalenderChemie,1898,vol.301,p.133

[5]ChemischeBerichte,1891,vol.24,p.1623

[6]KobunshiKagaku,1951,vol.8,p.467,469

[7]Chem.Abstr.,1953,p.9663

[8]JournaloftheAmericanChemicalSociety,1939,vol.61,p.1713

[9]Patent:US2848456,1956,,

[10]YakugakuZasshi,1952,vol.72,p.490

[11]Chem.Abstr.,1953,p.6418

[12]JournaloftheAmericanChemicalSociety,1951,vol.73,p.1838

[13]JournaloftheAmericanChemicalSociety,1949,vol.61,p.961

[14]Sovesc.PiridinaChinolinaRiga,1957,p.119,122

[15]Chem.Abstr.,1961,p.16546

[16]Z.obs.Chim.,1957,vol.27,p.2974,engl.Ausg.S.3005

[17]KogyoKagakuZasshi,1954,vol.57,p.902

[18]Chem.Abstr.,1956,p.999

[19]CHEMTECH,1955,vol.7,p.511,517

[20]KogyoKagakuZasshi,1954,vol.57,p.902

[21]Chem.Abstr.,1956,p.999

[22]JustusLiebigsAnnalenderChemie,1951,vol.573,p.85,90

[23]JustusLiebigsAnnalenderChemie,1952,vol.578,p.171,174

[24]Patent:US2512660,1946,,

[25]Patent:CN106748977,2017,A,.Locationinpatent:Page/Pagecolumn2

[26]Patent:CN107827813,2018,A,.Locationinpatent:Paragraph0009

[1]OrganicLetters,2007,vol.9,#6,p.1165-1167

Downstream Synthesis Route

[1]Shapiroetal.[JournaloftheAmericanPharmaceuticalAssociation(1912),1957,vol.46,p.333,335]Nortonetal.[JournaloftheAmericanChemicalSociety,1946,vol.68,p.1572,1575]

103-74-2    2908-71-6   
1-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-2-(2-hydroxy-ethyl)-pyridinium;bromidehydrobromide 

[1]JournalofOrganicChemistry,1939,vol.4,p.365,373

[1]Patent:US2018/72670,2018,A1.Locationinpatent:Paragraph0096-0097

[2]JournalofMedicinalChemistry,2019,vol.62,p.3707-3721

[3]YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1952,vol.72,p.490    Chem.Abstr.,1953,p.6418

[4]Chimica,1958,vol.34,p.146

[5]JournaloftheChemicalSociety.PerkinTransactions2(2001),2001,p.778-781

[6]JournalofMedicinalChemistry,2011,vol.54,p.4721-4734

[1]Wrobel,JerzyT.;Hejchman,Elzbieta[Synthesis,1987,#5,p.452-455]

[2]CurrentPatentAssignee:FirmenichInternationalSA-US2006/263411,2006,A1Locationinpatent:Page/Pagecolumn37

[3]CurrentPatentAssignee:MAPIPHARMALTD.-WO2016/132343,2016,A1Locationinpatent:Page/Pagecolumn21;24;25

103-74-2    42074-68-0    196814-73-0   
(S)-2-(2-Benzoyl-phenylamino)-3-4-(2-pyridin-2-yl-ethoxy)-phenyl-propionicacid 

[1]JournalofMedicinalChemistry,1998,vol.41,p.5037-5054

Literature

Title: Nitric oxide reactivity of copper(II) complexes of bidentate amine ligands: effect of chelate ring size on the stability of a [Cu(II)-NO] intermediate.

Journal: Dalton transactions (Cambridge, England : 2003) 20120821

Title: Bis(acetato-κO)bis-[2-(pyridin-2-yl)ethanol-κ(2)N,O]copper(II).

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: Bis[μ-2-(pyridin-2-yl)ethano-lato]bis-[bromidocopper(II)].

Journal: Acta crystallographica. Section E, Structure reports online 20111101

Title: Bis[2-(pyridin-2-yl)ethanol-κN,O]bis-(thio-cyanato-κN)nickel(II).

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Nuclearity of nickel and mixed sodium-nickel complexes: dependence on the spacer in chelating pyridine-alcoholate ligands.

Journal: Chemical communications (Cambridge, England) 20100921

Title: Family of Mn(III)(2)Ln(2)(mu(4)-O) compounds: syntheses, structures, and magnetic properties.

Journal: Inorganic chemistry 20100607

Title: Confirming urinary excretion of mephentermine and phentermine following the ingestion of oxethazaine by gas chromatography-mass spectrometry analysis.

Journal: Journal of analytical toxicology 20100301

Title: Bis(dicyanamido-κN)bis-[2-(2-hydroxy-ethyl)pyridine-κN,O]nickel(II).

Journal: Acta crystallographica. Section E, Structure reports online 20091201

Title: Vapor-diffusion-mediated single crystal-to-single crystal transformation of a discrete dimeric copper(II) complex to a discrete tetrameric copper(II) complex.

Journal: Inorganic chemistry 20090601

Title: 2,2'-Diamino-N,N'-(o-phenyl-ene)di-benz-amide.

Journal: Acta crystallographica. Section E, Structure reports online 20090401

Title: Oxethazaine as the source of mephentermine and phentermine in athlete's urine.

Journal: Forensic science international 20090310

Title: Bis[2-(2-hydroxyethyl)pyridinium] mu-decavanadato-bis[pentaaquamanganate(II)] tetrahydrate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20090201

Title: Comparing pain control and ability to eat and drink with standard therapy vs Gelclair: a preliminary, double centre, randomised controlled trial on patients with radiotherapy-induced oral mucositis.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20070401

Title: Palladium-catalyzed 2-pyridylmethyl transfer from 2-(2-pyridyl)ethanol derivatives to organic halides by chelation-assisted cleavage of unstrained C(sp3 )--C(sp3) bonds.

Journal: Angewandte Chemie (International ed. in English) 20070101

Title: Combinatorial computational approaches to identify tetracycline derivatives as flavivirus inhibitors.

Journal: PloS one 20070101

Title: Exploration of orally available calpain inhibitors. Part 3: Dipeptidyl alpha-ketoamide derivatives containing pyridine moiety.

Journal: Bioorganic & medicinal chemistry 20060815

Title: Intrahepatic flow disturbance: possibility of a hidden cause of drug toxicity.

Journal: Journal of pharmacological sciences 20060301

Title: Mechanisms involved in the contraction of intrahepatic portal vein branches by clomipramine and oxethazaine in isolated perfused rat livers.

Journal: Journal of pharmacological sciences 20050601

Title: Single-molecule magnets: structure and properties of [Mn18O14(O2CMe)18(hep)4(hepH)2(H2O)2](ClO4)2 with spin S = 13.

Journal: Inorganic chemistry 20050207

Title: [Clinical study on the pharmacological treatment of hemorrhoids with 0.25% oxethacaine chlorhydrate].

Journal: La Clinica terapeutica 20041001

Title: Large spin differences in structurally related Fe6 molecular clusters and their magnetostructural explanation.

Journal: Inorganic chemistry 20040906

Title: Design and synthesis of a novel family of triazine-based inhibitors of sorbitol dehydrogenase with oral activity: 1-[4-[3R,5S-dimethyl-4-(4-methyl-[1,3,5]triazin-2-yl)-piperazin-1-yl]-[1,3,5]triazin-2-yl]-(R) ethanol.

Journal: Bioorganic & medicinal chemistry 20030915

Title: Quantum tunneling of magnetization in a new [Mn18]2+ single-molecule magnet with s = 13.

Journal: Journal of the American Chemical Society 20020821

Title: Biphasic effects of oxethazaine, a topical anesthetic, on the intracellular Ca(2+) concentration of PC12 cells.

Journal: Biochemical pharmacology 20020815

Title: Metabolism of a thiazole benzenesulfonamide derivative, a potent and elective agonist of the human beta3-adrenergic receptor, in rats: identification of a novel isethionic acid conjugate.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020701

Title: Single-molecule magnets: a new family of Mn(12) clusters of formula [Mn(12)O(8)X(4)(O(2)CPh)(8)L(6)].

Journal: Journal of the American Chemical Society 20020410

Title: Effects of betahistine and of its metabolites on vestibular sensory organs.

Journal: Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 20010601

Title: Binding affinity profile of betahistine and its metabolites for central histamine receptors of rodents.

Journal: Pharmacological research 20010401

Title: [[Separation of oxetacaine and its metabolites] ].

Journal: Die Pharmazie 20010101

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Tags:103-74-2 Molecular Formula|103-74-2 MDL|103-74-2 SMILES|103-74-2 2-Pyridineethanol