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104-03-0,MFCD00007383
Catalog No.:AA003LTE

104-03-0 | 4-Nitrophenylacetic acid

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10g
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$6.00   $4.00
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25g
97%
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$13.00   $9.00
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100g
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500g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003LTE
Chemical Name:
4-Nitrophenylacetic acid
CAS Number:
104-03-0
Molecular Formula:
C8H7NO4
Molecular Weight:
181.1455
MDL Number:
MFCD00007383
SMILES:
OC(=O)Cc1ccc(cc1)[N+](=O)[O-]
NSC Number:
5398
Properties
Properties
 
BP:
377.6 °C at 760 mmHg  
Form:
Solid  
MP:
150-155 °C  
Refractive Index:
1.5468 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
203  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.4  

Literature

Title: Species difference of esterase expression and hydrolase activity in plasma.

Journal: Journal of pharmaceutical sciences 20121001

Title: Carbonic anhydrase immobilized on encapsulated magnetic nanoparticles for CO2 sequestration.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120917

Title: Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols and their derivatives including natural products: vidalol B.

Journal: European journal of medicinal chemistry 20120801

Title: Expression and characterization of codon-optimized carbonic anhydrase from Dunaliella species for CO(2) sequestration application.

Journal: Applied biochemistry and biotechnology 20120801

Title: The impact of heavy metals on the activity of carbonic anhydrase from rainbow trout (Oncorhynchus mykiss) kidney.

Journal: Toxicology and industrial health 20120501

Title: Paraoxonase 1 in chronic kidney failure.

Journal: Journal of lipids 20120101

Title: Characterization of a novel immobilized biocatalyst obtained by matrix-assisted refolding of recombinant polyhydroxyoctanoate depolymerase from Pseudomonas putida KT2442 isolated from inclusion bodies.

Journal: Journal of industrial microbiology & biotechnology 20110901

Title: Molecular mechanism of uncaging CO2 from nitrophenylacetate provides general guidelines for improved ortho-nitrobenzyl cages.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20110801

Title: In Vitro inhibition of human carbonic anhydrase I and II isozymes with natural phenolic compounds.

Journal: Chemical biology & drug design 20110601

Title: Acylation of heteroaromatic amines: facile and efficient synthesis of a new class of 1,2,3-triazolo[4,5-b]pyridine and pyrazolo[4,3-b]pyridine derivatives.

Journal: Molecules (Basel, Switzerland) 20110504

Title: Synthesis and characterization of novel 2, 2'-bipyrimidine fluorescent derivative for protein binding.

Journal: Chemistry Central journal 20110101

Title: Cured of 'stickiness', poly-L β-hairpin is promoted with LL-to-DD mutation as a protein and a hydrolase mimic.

Journal: The journal of physical chemistry. B 20101223

Title: Continuous reduction of plasma paraoxonase activity with increasing dialysis vintage in hemodialysis patients.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20101201

Title: A novel and one-pot synthesis of new 1-tosyl pyrrol-2-one derivatives and analysis of carbonic anhydrase inhibitory potencies.

Journal: Bioorganic & medicinal chemistry 20100615

Title: Carbonic anhydrase inhibitors: Inhibition of human erythrocyte isozymes I and II with a series of phenolic acids.

Journal: Chemical biology & drug design 20100501

Title: Hyperthermostable acetyl xylan esterase.

Journal: Microbial biotechnology 20100101

Title: Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours.

Journal: British journal of cancer 20090818

Title: Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.

Journal: Bioorganic & medicinal chemistry 20090415

Title: Partially irreversible inactivation of mitochondrial aldehyde dehydrogenase by nitroglycerin.

Journal: The Journal of biological chemistry 20081107

Title: CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay.

Journal: Chembiochem : a European journal of chemical biology 20081103

Title: A new lipase isolated from oleaginous seeds from Pachira aquatica (Bombacaceae).

Journal: Applied biochemistry and biotechnology 20080901

Title: Ethyl 4-nitro-phenyl-acetate.

Journal: Acta crystallographica. Section E, Structure reports online 20080201

Title: Effects of some metals on carbonic anhydrase from brains of rainbow trout.

Journal: Biological trace element research 20080101

Title: Purification and some kinetic properties of carbonic anhydrase from rainbow trout (Oncorhynchus mykiss) liver and metal inhibition.

Journal: Protein and peptide letters 20080101

Title: Synthesis of cyclic oligomers from histidine-derived building blocks using dynamic combinatorial chemistry.

Journal: The Journal of organic chemistry 20071123

Title: Specificity of procaine and ester hydrolysis by human, minipig, and rat skin and liver.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20071101

Title: Change in the acid hydrolysis mechanism of esters enforced by strongly acid microemulsions.

Journal: The journal of physical chemistry. B 20071004

Title: Involvement of up-regulation of hepatic breast cancer resistance protein in decreased plasma concentration of 7-ethyl-10-hydroxycamptothecin (SN-38) by coadministration of S-1 in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070901

Title: Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Aspirin is a substrate for paraoxonase-like activity: implications in atherosclerosis.

Journal: Atherosclerosis 20070401

Title: Increased alanine concentration is associated with exposure to fenitrothion but not carbamates in Chironomus riparius larvae.

Journal: Ecotoxicology and environmental safety 20070301

Title: Accuracy and biological variation of human serum paraoxonase 1 activity and polymorphism (Q192R) by kinetic enzyme assay.

Journal: Clinical chemistry 20070201

Title: Exploiting the yeast L-A viral capsid for the in vivo assembly of chimeric VLPs as platform in vaccine development and foreign protein expression.

Journal: PloS one 20070101

Title: Cyclodecyl 4-nitrophenylacetate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20061001

Title: Examination of two independent kinetic assays for determining the inhibition of carbonic anhydrases I and II: structure-activity comparison of sulfamates and sulfamides.

Journal: Chemical biology & drug design 20060801

Title: Identification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050801

Title: From decanoate micelles to decanoic acid/dodecylbenzenesulfonate vesicles.

Journal: Langmuir : the ACS journal of surfaces and colloids 20050705

Title: Acidic residues emulate a phosphorylation switch to enhance the activity of rat hepatic neutral cytosolic cholesterol esterase.

Journal: Biochimica et biophysica acta 20050501

Title: Plasma and whole blood pharmacokinetics of topiramate: the role of carbonic anhydrase.

Journal: Epilepsy research 20050201

Title: Reduction of methemoglobin via electron transfer from photoreduced flavin: restoration of O2-binding of concentrated hemoglobin solution coencapsulated in phospholipid vesicles.

Journal: Bioconjugate chemistry 20040101

Title: Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9A resolution.

Journal: Journal of molecular biology 20030711

Title: Lack of association between serum paraoxonase 1 activities and increased oxidized low-density lipoprotein levels in impaired glucose tolerance and newly diagnosed diabetes mellitus.

Journal: The Journal of clinical endocrinology and metabolism 20030401

Title: Biochemical detection of esterases in the adult female integument of organophosphate-resistant Boophilus microplus (Acari: Ixodidae).

Journal: Journal of medical entomology 20030101

Title: Mapping of the active site of rat kidney gamma-glutamyl transpeptidase using activated esters and their amide derivatives.

Journal: Bioorganic & medicinal chemistry 20021201

Title: Secreted and tumour targeted human carboxylesterase for activation of irinotecan.

Journal: British journal of cancer 20020909

Title: Studies on the catalytic behaviour of a cholinesterase-like abzyme in an AOT microemulsion system.

Journal: Journal of biotechnology 20020807

Title: Reactions of oximate alpha-nucleophiles with esters: evidence from solvation effects for substantial decoupling of desolvation and bond formation.

Journal: Journal of the American Chemical Society 20020731

Title: [Synthesis and fluorescence property of complexes of rare-earth with p-nitrophenylacetic acid].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20020601

Title: Human and rodent carboxylesterases: immunorelatedness, overlapping substrate specificity, differential sensitivity to serine enzyme inhibitors, and tumor-related expression.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020501

Title: Determinants of the cytotoxicity of irinotecan in two human colorectal tumor cell lines.

Journal: Cancer chemotherapy and pharmacology 20020401

Title: Carbonic anhydrase activators: design of high affinity isozymes I, II, and IV activators, incorporating tri-/tetrasubstituted-pyridinium-azole moieties.

Journal: Journal of medicinal chemistry 20020117

Title: The stability of methacrylate biomaterials when enzyme challenged: kinetic and systematic evaluations.

Journal: Journal of biomedical materials research 20011215

Title: Assay of serum arylesterase activity by fitting to the reaction curve with an integrated rate equation.

Journal: Clinica chimica acta; international journal of clinical chemistry 20011201

Title: Regulation of rat carboxylesterase expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): a dose-dependent decrease in mRNA levels but a biphasic change in protein levels and activity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20011101

Title: [Synthesis, characterization and fluorescence property of europium ternary complex p-nitrophenylacetic acid and 1, 10-phenanthroline].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20011001

Title: Mutation of residues 423 (Met/Ile), 444 (Thr/Met), and 506 (Asn/Ser) confer cholesteryl esterase activity on rat lung carboxylesterase. Ser-506 is required for activation by cAMP-dependent protein kinase.

Journal: The Journal of biological chemistry 20010831

Title: Synthesis, molecular modeling, and structure-activity relationship of benzophenone-based CAAX-peptidomimetic farnesyltransferase inhibitors.

Journal: Journal of medicinal chemistry 20010830

Title: On the occurrence of multiple isoprenylated cysteine methyl ester hydrolase activities in bovine adrenal medulla.

Journal: Biochemical and biophysical research communications 20010601

Title: Biochemical mechanisms of resistance in strains of Oryzaephilus surinamensis (Coleoptera: Silvanidae) resistant to malathion and chlorpyrifos-methyl.

Journal: Journal of economic entomology 20010601

Title: Carbonic anhydrase from bovine bone.

Journal: Preparative biochemistry & biotechnology 20010201

Title: Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis.

Journal: Pharmacogenetics 20000201

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