Home Amines 111821-58-0
111821-58-0,MFCD00078584
Catalog No.:AA008SD2

111821-58-0 | (S)-(-)-3-AMINO-1-HYDROXYPYRROLIDIN-2-ONE

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10mg
≥98%(HPLC)
in stock  
$165.00   $115.00
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50mg
≥98%(HPLC)
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$515.00   $360.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA008SD2
Chemical Name:
(S)-(-)-3-AMINO-1-HYDROXYPYRROLIDIN-2-ONE
CAS Number:
111821-58-0
Molecular Formula:
C4H8N2O2
Molecular Weight:
116.1185
MDL Number:
MFCD00078584
SMILES:
O=C1[C@@H](N)CCN1O
Properties
Computed Properties
 
Complexity:
115  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
XLogP3:
-1.5  

Literature

Title: B A Morrow, et al. (S)-(-)-HA-966, a gamma-hydroxybutyrate-like agent, prevents enhanced mesocorticolimbic dopamine metabolism and behavioral correlates of restraint stress, conditioned fear and cocaine sensitization. J Pharmacol Exp Ther. 1997 Nov;283(2):712-21.

Title: L Singh, et al. Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative. Proc Natl Acad Sci U S A. 1990 Jan;87(1):347-51.

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SDS
Tags:111821-58-0 Molecular Formula|111821-58-0 MDL|111821-58-0 SMILES|111821-58-0 (S)-(-)-3-AMINO-1-HYDROXYPYRROLIDIN-2-ONE