Name: Name:5,7-Dichlorothiazolo[4,5-d]pyrimidine
Brand: AABLOCKS
SKU: AA0009E2
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0009E2

Chemical Name: 5,7-Dichlorothiazolo[4,5-d]pyrimidine

CAS Number: 1137278-39-7

Molecular Formula: C5HCl2N3S

Molecular Weight: 206.0525

MDL Number: MFCD16658954

SMILES: Clc1nc(Cl)c2c(n1)ncs2

Properties

Complexity: 159

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 11

Hydrogen Bond Acceptor Count: 4

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 0

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.9

Downstream Synthesis Route

110-91-8

1137278-39-7

1137278-42-2

[1]CurrentPatentAssignee:UNIVERSITYOFBASEL-WO2010/52569,2010,A2Locationinpatent:Page/Pagecolumn235

[2]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2009/42607,2009,A1Locationinpatent:Page/Pagecolumn68

[3]Murray,JeremyM.;Sweeney,ZacharyK.;Chan,BryanK.;Balazs,Mercedesz;Bradley,Erin;Castanedo,Georgette;Chabot,Christine;Chantry,David;Flagella,Michael;Goldstein,DavidM.;Kondru,Rama;Lesnick,John;Li,Jun;Lucas,MatthewC.;Nonomiya,Jim;Pang,Jodie;Price,Stephen;Salphati,Laurent;Safina,Brian;Savy,PascalP.A.;Seward,EileenM.;Ultsch,Mark;Sutherlin,DanielP.[JournalofMedicinalChemistry,2012,vol.55,#17,p.7686-7695]

7464-09-7

1137278-39-7

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2009/42607,2009,A1Locationinpatent:Page/Pagecolumn68

[2]CurrentPatentAssignee:UNIVERSITYOFBASEL-WO2010/52569,2010,A2Locationinpatent:Page/Pagecolumn234

1137278-39-7

1093075-00-3

[1]Murray,JeremyM.;Sweeney,ZacharyK.;Chan,BryanK.;Balazs,Mercedesz;Bradley,Erin;Castanedo,Georgette;Chabot,Christine;Chantry,David;Flagella,Michael;Goldstein,DavidM.;Kondru,Rama;Lesnick,John;Li,Jun;Lucas,MatthewC.;Nonomiya,Jim;Pang,Jodie;Price,Stephen;Salphati,Laurent;Safina,Brian;Savy,PascalP.A.;Seward,EileenM.;Ultsch,Mark;Sutherlin,DanielP.[JournalofMedicinalChemistry,2012,vol.55,#17,p.7686-7695]

1137278-39-7

1257294-85-1

[1]Murray,JeremyM.;Sweeney,ZacharyK.;Chan,BryanK.;Balazs,Mercedesz;Bradley,Erin;Castanedo,Georgette;Chabot,Christine;Chantry,David;Flagella,Michael;Goldstein,DavidM.;Kondru,Rama;Lesnick,John;Li,Jun;Lucas,MatthewC.;Nonomiya,Jim;Pang,Jodie;Price,Stephen;Salphati,Laurent;Safina,Brian;Savy,PascalP.A.;Seward,EileenM.;Ultsch,Mark;Sutherlin,DanielP.[JournalofMedicinalChemistry,2012,vol.55,#17,p.7686-7695]

[2]Murray,JeremyM.;Sweeney,ZacharyK.;Chan,BryanK.;Balazs,Mercedesz;Bradley,Erin;Castanedo,Georgette;Chabot,Christine;Chantry,David;Flagella,Michael;Goldstein,DavidM.;Kondru,Rama;Lesnick,John;Li,Jun;Lucas,MatthewC.;Nonomiya,Jim;Pang,Jodie;Price,Stephen;Salphati,Laurent;Safina,Brian;Savy,PascalP.A.;Seward,EileenM.;Ultsch,Mark;Sutherlin,DanielP.[JournalofMedicinalChemistry,2012,vol.55,#17,p.7686-7695]

1137278-39-7

1257382-37-8

[1]Murray,JeremyM.;Sweeney,ZacharyK.;Chan,BryanK.;Balazs,Mercedesz;Bradley,Erin;Castanedo,Georgette;Chabot,Christine;Chantry,David;Flagella,Michael;Goldstein,DavidM.;Kondru,Rama;Lesnick,John;Li,Jun;Lucas,MatthewC.;Nonomiya,Jim;Pang,Jodie;Price,Stephen;Salphati,Laurent;Safina,Brian;Savy,PascalP.A.;Seward,EileenM.;Ultsch,Mark;Sutherlin,DanielP.[JournalofMedicinalChemistry,2012,vol.55,#17,p.7686-7695]

[2]Murray,JeremyM.;Sweeney,ZacharyK.;Chan,BryanK.;Balazs,Mercedesz;Bradley,Erin;Castanedo,Georgette;Chabot,Christine;Chantry,David;Flagella,Michael;Goldstein,DavidM.;Kondru,Rama;Lesnick,John;Li,Jun;Lucas,MatthewC.;Nonomiya,Jim;Pang,Jodie;Price,Stephen;Salphati,Laurent;Safina,Brian;Savy,PascalP.A.;Seward,EileenM.;Ultsch,Mark;Sutherlin,DanielP.[JournalofMedicinalChemistry,2012,vol.55,#17,p.7686-7695]

1137278-39-7 | 5,7-Dichlorothiazolo[4,5-d]pyrimidine