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114-76-1,MFCD00149109
Catalog No.:AA000A7D

114-76-1 | Sodium phenylpyruvate monohydrate

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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000A7D
Chemical Name:
Sodium phenylpyruvate monohydrate
CAS Number:
114-76-1
Molecular Formula:
C9H7NaO3
Molecular Weight:
186.1398
MDL Number:
MFCD00149109
SMILES:
O=C(C(=O)[O-])Cc1ccccc1.[Na+]
Properties
Properties
 
Form:
Solid  
MP:
>300 °C(lit.)  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
185  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:UNIVERSITYOFCALIFORNIA-US2007/60773,2007,A1Locationinpatent:Page/Pagecolumn8-10

143-66-8    16858-01-8    114-76-1   
cobalt(II)perchloratehexahydrate 
  1418284-81-7 

[1]EuropeanJournalofInorganicChemistry,2012,p.5843-5853

Literature

Title: Phenylpyruvic acid decreases glucose-6-phosphate dehydrogenase activity in rat brain.

Journal: Cellular and molecular neurobiology 20121001

Title: Characterization of D-lactate dehydrogenase from Pediococcus acidilactici that converts phenylpyruvic acid into phenyllactic acid.

Journal: Biotechnology letters 20120501

Title: Resolving phenylalanine metabolism sheds light on natural synthesis of penicillin G in Penicillium chrysogenum.

Journal: Eukaryotic cell 20120201

Title: Characterization of D-lactate dehydrogenase producing D-3-phenyllactic acid from Pediococcus pentosaceus.

Journal: Bioscience, biotechnology, and biochemistry 20120101

Title: Novel fungal phenylpyruvate reductase belongs to d-isomer-specific 2-hydroxyacid dehydrogenase family.

Journal: Biochimica et biophysica acta 20111201

Title: Exploring the catalytic potential of the 3-His mononuclear nonheme Fe(II) center: discovery and characterization of an unprecedented maltol cleavage activity.

Journal: Journal of inorganic biochemistry 20110901

Title: Identification of genes in the phenylalanine metabolic pathway by ectopic expression of a MYB transcription factor in tomato fruit.

Journal: The Plant cell 20110701

Title: Novel potential markers of nasopharyngeal carcinoma for diagnosis and therapy.

Journal: Clinical biochemistry 20110601

Title: Study on urinary metabolic profile of phenylketonuria by micellar electrokinetic capillary chromatography with dual electrochemical detection--potential clinical application in fast diagnosis of phenylketonuria.

Journal: Analytica chimica acta 20110523

Title: Efficient conversion of phenylpyruvic acid to phenyllactic acid by using whole cells of Bacillus coagulans SDM.

Journal: PloS one 20110101

Title: Bioconversion of phenylpyruvate to phenyllactate: gene cloning, expression, and enzymatic characterization of D- and L1-lactate dehydrogenases from Lactobacillus plantarum SK002.

Journal: Applied biochemistry and biotechnology 20100901

Title: Kinetic-based high-throughput screening assay to discover novel classes of macrophage migration inhibitory factor inhibitors.

Journal: Journal of biomolecular screening 20100401

Title: Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid.

Journal: Experimental & molecular medicine 20100227

Title: 3-Phenyllactic acid production by substrate feeding and pH-control in fed-batch fermentation of Lactobacillus sp. SK007.

Journal: Bioresource technology 20091101

Title: Purification and partial characterization of Lactobacillus species SK007 lactate dehydrogenase (LDH) catalyzing phenylpyruvic acid (PPA) conversion into phenyllactic acid (PLA).

Journal: Journal of agricultural and food chemistry 20080409

Title: Mechanism of benzaldehyde lyase studied via thiamin diphosphate-bound intermediates and kinetic isotope effects.

Journal: Biochemistry 20080325

Title: Crystal structure of VioE, a key player in the construction of the molecular skeleton of violacein.

Journal: The Journal of biological chemistry 20080307

Title: Organic acid concentrations in amniotic fluid found in normal and Down syndrome pregnancies.

Journal: Fetal diagnosis and therapy 20080201

Title: Near-ultraviolet photolysis of beta-phenylpyruvic acid generates free radicals and results in DNA damage.

Journal: Journal of photochemistry and photobiology. B, Biology 20071214

Title: Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction?

Journal: Biochemistry 20070821

Title: Nucleophile selectivity of chorismate-utilizing enzymes.

Journal: Chembiochem : a European journal of chemical biology 20070416

Title: Biotransformation of phenylpyruvic acid to phenyllactic acid by growing and resting cells of a Lactobacillus sp.

Journal: Biotechnology letters 20070401

Title: Characterization and application of D-amino acid oxidase and catalase within permeabilized Pichia pastoris cells in bioconversions.

Journal: Applied biochemistry and biotechnology 20070301

Title: Iron-catalyzed C2-C3 bond cleavage of phenylpyruvate with O2: insight into aliphatic C-C bond-cleaving dioxygenases.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: Chemical conversion of alpha-amino acids into alpha-keto acids by 4,5-epoxy-2-decenal.

Journal: Journal of agricultural and food chemistry 20060809

Title: Engineered phenylalanine dehydrogenase in organic solvents: homogeneous and biphasic enzymatic reactions.

Journal: Organic & biomolecular chemistry 20051221

Title: Plant-derived anti-inflammatory compounds affect MIF tautomerase activity.

Journal: International immunopharmacology 20050501

Title: A molecularly imprinted polymer-based synthetic transaminase.

Journal: Journal of the American Chemical Society 20040714

Title: Estrogen-inducible uterine flavonoid binding sites: is it time to reconsider?

Journal: The Journal of steroid biochemistry and molecular biology 20040401

Title: Beta-phenylpyruvate and glucose uptake in isolated mouse soleus muscle and cultured C2C12 muscle cells.

Journal: Journal of cellular biochemistry 20031201

Title: Glutamine:phenylpyruvate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8.

Journal: Journal of biochemistry 20031201

Title: Effects of phenylalanine and phenylpyruvate on ATP-ADP hydrolysis by rat blood serum.

Journal: Amino acids 20030601

Title: Characterization of the inhibition of pyruvate kinase caused by phenylalanine and phenylpyruvate in rat brain cortex.

Journal: Brain research 20030411

Title: Glucose-lowering effect of beta-phenylpyruvate in neonatal mice: a possible mechanism for phenylketonuria-related neurodegenerative changes.

Journal: Brain research. Developmental brain research 20030314

Title: Asbjørn Følling and the discovery of phenylketonuria.

Journal: Journal of the history of the neurosciences 20030301

Title: (4-Hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis: the basis for ordered substrate addition.

Journal: Biochemistry 20030225

Title: [Characterization of phenylpyruvic acid and beta-benzyl phenylpyruvic acid by UV, IR, MS, and 1H NMR].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20030201

Title: p-Sulfooxyphenylpyruvic acid from the red macro alga Ceratodictyon spongiosum and its sponge symbiont Haliclona cymaeformis.

Journal: Phytochemistry 20020601

Title: Aromatic amino acid biosynthesis and production of related compounds from p-hydroxyphenylpyruvic acid by rumen bacteria, protozoa and their mixture.

Journal: Amino acids 20020101

Title: Phenylalanine and phenylpyruvate inhibit ATP diphosphohydrolase from rat brain cortex.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20011101

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