Home Amines 13115-71-4
13115-71-4,MFCD00150855
Catalog No.:AA000VK7

13115-71-4 | Glycyl-l-glutamine

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1g
98%
in stock  
$23.00   $16.00
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5g
97%
in stock  
$23.00   $16.00
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10g
97%
in stock  
$44.00   $31.00
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25g
97%
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$73.00   $51.00
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100g
98%
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$261.00   $183.00
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500g
98%
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$809.00   $567.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000VK7
Chemical Name:
Glycyl-l-glutamine
CAS Number:
13115-71-4
Molecular Formula:
C7H13N3O4
Molecular Weight:
203.1958
MDL Number:
MFCD00150855
SMILES:
NCC(=O)N[C@H](C(=O)O)CCC(=O)N
Properties
Properties
 
BP:
643.1°C at 760 mmHg  
Form:
Solid  
MP:
194 °C  
Refractive Index:
-7 ° (C=3, 1mol/L HCl)  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
241  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  
XLogP3:
-4.6  

Literature

Title: A liquid chromatography-tandem mass spectrometry assay for detection and quantitation of the dipeptide Gly-Gln in rat brain.

Journal: Analytical biochemistry 20120615

Title: Influence of TiO2 on prebiotic thermal synthesis of the Gly-Gln polymer.

Journal: Amino acids 20120601

Title: Glutamine: A novel approach to chemotherapy-induced toxicity.

Journal: Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20120101

Title: Functional and structural determinants of reverse operation in the pH-dependent oligopeptide transporter PepT1.

Journal: Cellular and molecular life sciences : CMLS 20110901

Title: Enteral supplementation with glycyl-glutamine improves intestinal barrier function after liver transplantation in rats.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20110801

Title: Residues R282 and D341 act as electrostatic gates in the proton-dependent oligopeptide transporter PepT1.

Journal: The Journal of physiology 20110201

Title: Unified modeling of the mammalian and fish proton-dependent oligopeptide transporter PepT1.

Journal: Channels (Austin, Tex.) 20110101

Title: Targeted Therapy of Ewing's Sarcoma.

Journal: Sarcoma 20110101

Title: Glutamine supplementation in sick children: is it beneficial?

Journal: Journal of nutrition and metabolism 20110101

Title: Glycyl-glutamine (beta-endorphin(30-31)) inhibits morphine-induced dopamine efflux in the nucleus accumbens.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100501

Title: The impact of glutamine dipeptide-supplemented parenteral nutrition on outcomes of surgical patients: a meta-analysis of randomized clinical trials.

Journal: JPEN. Journal of parenteral and enteral nutrition 20100101

Title: Mammalian oocytes are targets for prostaglandin E2 (PGE2) action.

Journal: Reproductive biology and endocrinology : RB&E 20100101

Title: Effects of dietary glycyl-glutamine on growth performance, small intestinal integrity, and immune responses of weaning piglets challenged with lipopolysaccharide.

Journal: Journal of animal science 20091201

Title: Electrophysiological characterization of electrolyte and nutrient transport across the small intestine in horses.

Journal: Journal of animal physiology and animal nutrition 20090601

Title: Inhibition of intracellular dipeptide hydrolysis uncovers large outward transport currents of the peptide transporter PEPT1 in Xenopus oocytes.

Journal: Pflugers Archiv : European journal of physiology 20090201

Title: Amino acids - Guidelines on Parenteral Nutrition, Chapter 4.

Journal: German medical science : GMS e-journal 20090101

Title: Substrate-induced changes in the density of peptide transporter PEPT1 expressed in Xenopus oocytes.

Journal: American journal of physiology. Cell physiology 20081101

Title: Characterisation of electrogenic nutrient absorption in the Cftr TgH(neoim)Hgu mouse model.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20080801

Title: Cyclo-glycyl-glutamine inhibits ethanol intake in P and Sprague-Dawley rats.

Journal: Peptides 20080301

Title: Glycyl-glutamine reduces ethanol intake at three reward sites in P rats.

Journal: Alcohol (Fayetteville, N.Y.) 20080301

Title: Synthesis and characterization of complex of glycyl-L-glutamine and bismuth trichloride.

Journal: Protein and peptide letters 20080101

Title: Tripeptides of RS1 (RSC1A1) inhibit a monosaccharide-dependent exocytotic pathway of Na+-D-glucose cotransporter SGLT1 with high affinity.

Journal: The Journal of biological chemistry 20070928

Title: Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake.

Journal: The Journal of pharmacology and experimental therapeutics 20070801

Title: [Protective effects of glycyl-glutamine dipeptide supplement on the heart function in burn rats].

Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20070801

Title: The effect of glutamine-supplemented total parenteral nutrition on nutrition and intestinal absorptive function in a rat model.

Journal: Pediatric surgery international 20060601

Title: Enteral feeding of glycyl-glutamine dipeptide improves the structure and absorptive function of the small intestine after allogenetic liver transplantation in rats.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20060501

Title: High-affinity peptide transporter PEPT2 (SLC15A2) of the zebrafish Danio rerio: functional properties, genomic organization, and expression analysis.

Journal: Physiological genomics 20060214

Title: Glycyl-glutamine inhibits nicotine conditioned place preference and withdrawal.

Journal: European journal of pharmacology 20060113

Title: Glycyl-glutamine, an endogenous beta-endorphin-derived peptide, inhibits morphine-induced conditioned place preference, tolerance, dependence, and withdrawal.

Journal: The Journal of pharmacology and experimental therapeutics 20051101

Title: Glycyl-glutamine in nucleus accumbens reduces ethanol intake in alcohol preferring (P) rats.

Journal: Brain research 20051005

Title: Glycyl-L-glutamine disposition in rat choroid plexus epithelial cells in primary culture: role of PEPT2.

Journal: Pharmaceutical research 20050801

Title: Mouse embryo development following IVF in media containing either L-glutamine or glycyl-L-glutamine.

Journal: Human reproduction (Oxford, England) 20050501

Title: Enhanced effect of glycyl-L-glutamine on mouse preimplantation embryos in vitro.

Journal: Reproductive biomedicine online 20040701

Title: Direct visualization of peptide uptake activity in the central nervous system of the rat.

Journal: Neuroscience letters 20040624

Title: Randomized, double-blind, controlled study of glycyl-glutamine-dipeptide in the parenteral nutrition of patients with acute leukemia undergoing intensive chemotherapy.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20040301

Title: Glycyl-glutamine-supplemented long-term total parenteral nutrition selectively improves structure and function in heterotopic small-bowel autotransplantation in the pig.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20031201

Title: Choline potentiates the pressor response evoked by glycyl-glutamine or naloxone in haemorrhaged rats.

Journal: Clinical and experimental pharmacology & physiology 20030901

Title: Characterisation of intestinal peptide transporter of the Antarctic haemoglobinless teleost Chionodraco hamatus.

Journal: The Journal of experimental biology 20030201

Title: Perioperative GLY-GLN infusion diminishes the surgery-induced period of immunosuppression: accelerated restoration of the lipopolysaccharide-stimulated tumor necrosis factor-alpha response.

Journal: Annals of surgery 20030101

Title: Renal assimilation of short chain peptides: visualization of tubular peptide uptake.

Journal: Pharmaceutical research 20020801

Title: Characteristics of lysophosphatidylcholine in its inhibition of taurine uptake by human intestinal Caco-2 cells.

Journal: Bioscience, biotechnology, and biochemistry 20020401

Title: Bidirectional electrogenic transport of peptides by the proton-coupled carrier PEPT1 in Xenopus laevis oocytes: its asymmetry and symmetry.

Journal: The Journal of physiology 20011015

Title: No evidence for active peptide transport in forestomach epithelia of sheep.

Journal: Journal of animal physiology and animal nutrition 20011001

Title: Influence of glutamine and glycyl-glutamine on in vitro lymphocyte proliferation in children with solid tumors.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20010601

Title: Inhibition of interleukin-1beta and prostaglandin E(2) thermogenesis by glycyl-glutamine, a pro-opiomelanocortin-derived peptide.

Journal: Brain research 20010316

Title: Postoperative glycyl-glutamine infusion reduces immunosuppression: partial prevention of the surgery induced decrease in HLA-DR expression on monocytes.

Journal: Clinical nutrition (Edinburgh, Scotland) 20010201

Title: Effect of beta-endorphin C-terminal peptides on glucose uptake in isolated skeletal muscles of the mouse.

Journal: Peptides 19970101

Title: Unal CB1, et al. Beta-endorphin-induced cardiorespiratory depression is inhibited by glycyl-L-glutamine, a dipeptide derived from beta-endorphin processing.J Pharmacol Exp Ther. 1994 Nov;271(2):952-8

Title: Roth E, et al. Influence of two glutamine-containing dipeptides on growth of mammalian cells.In Vitro Cell Dev Biol. 1988 Jul;24(7):696-8.

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Tags:13115-71-4 Molecular Formula|13115-71-4 MDL|13115-71-4 SMILES|13115-71-4 Glycyl-l-glutamine