Title: 1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases.
Journal: Bioorganic & medicinal chemistry 20131201
Title: Adenosine A2 receptor-mediated regulation of renal hemodynamics and glomerular filtration rate is abolished in diabetes.
Journal: Advances in experimental medicine and biology 20130101
Title: Hypoxia/reoxygenation impairs memory formation via adenosine-dependent activation of caspase 1.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20121003
Title: Presynaptic inhibition of GABAergic synaptic transmission by adenosine in mouse hypothalamic hypocretin neurons.
Journal: Neuroscience 20120110
Title: A combination of ischemic preconditioning and allopurinol protects against ischemic injury through a nitric oxide-dependent mechanism.
Journal: Nitric oxide : biology and chemistry 20120101
Title: Adenosine modulates the excitability of layer II stellate neurons in entorhinal cortex through A1 receptors.
Journal: Hippocampus 20110301
Title: Adenosine reduces GABAergic IPSC frequency via presynaptic A₁ receptors in hypothalamic paraventricular neurons projecting to rostral ventrolateral medulla.
Journal: Neuroscience letters 20110218
Title: Adenosine receptor regulation of coronary blood flow in Ossabaw miniature swine.
Journal: The Journal of pharmacology and experimental therapeutics 20101201
Title: Adenosine receptor agonists affect taurine release from mouse brain stem slices in ischemia.
Journal: Amino acids 20100501
Title: Activity-dependent release of adenosine inhibits the glutamatergic synaptic transmission and plasticity in the hypothalamic hypocretin/orexin neurons.
Journal: Neuroscience 20090915
Title: The role of the basal forebrain adenosine receptors in sleep homeostasis.
Journal: Neuroreport 20090715
Title: Functional interaction between purinergic system and opioid withdrawal: in vitro evidence.
Journal: Current drug safety 20090501
Title: Activation of A(2) adenosine receptors dilates cortical efferent arterioles in mouse.
Journal: Kidney international 20090401
Title: MDA-MB-231 produces ATP-mediated ICAM-1-dependent facilitation of the attachment of carcinoma cells to human lymphatic endothelial cells.
Journal: American journal of physiology. Cell physiology 20081101
Title: Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
Journal: European journal of pharmacology 20080414
Title: Visualisation of the effects of dilazep on rat afferent and efferent arterioles in vivo.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080201
Title: Transformation products of extracellular NAD(+) in the rat liver: kinetics of formation and metabolic action.
Journal: Molecular and cellular biochemistry 20080101
Title: Protective effect of adenosine in diabetic neuropathic pain is mediated through adenosine A1-receptors.
Journal: Indian journal of physiology and pharmacology 20080101
Title: Sodium intake determines the role of adenosine A2 receptors in control of renal medullary perfusion in the rat.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071001
Title: Adenosine A2 receptor activation attenuates afferent arteriolar autoregulation during adenosine receptor saturation in rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20071001
Title: Effect of the adenosine A2a receptor antagonist 3,7-dimethyl-propargylxanthine on anxiety-like and depression-like behavior and alcohol consumption in Wistar Rats.
Journal: Alcoholism, clinical and experimental research 20070801
Title: Characterization of the potency, selectivity, and pharmacokinetic profile for six adenosine A2A receptor antagonists.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20070401
Title: Methotrexate regulates the expression of glucocorticoid receptor alpha and beta isoforms in normal human peripheral mononuclear cells and human lymphocyte cell lines in vitro.
Journal: Molecular immunology 20070301
Title: Hypertonic stress regulates T-cell function by the opposing actions of extracellular adenosine triphosphate and adenosine.
Journal: Shock (Augusta, Ga.) 20070301
Title: Intrahepatic adenosine-mediated activation of hepatorenal reflex is via A1 receptors in rats.
Journal: Canadian journal of physiology and pharmacology 20061101
Title: Contribution of hepatic adenosine A1 receptors to renal dysfunction associated with acute liver injury in rats.
Journal: Hepatology (Baltimore, Md.) 20061001
Title: Neuroprotective effects of hibernation-regulating substances against low-temperature-induced cell death in cultured hamster hippocampal neurons.
Journal: Brain research 20060907
Title: Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation.
Journal: Kidney international 20060801
Title: Inhibitory responses to exogenous adenosine in murine proximal and distal colon.
Journal: British journal of pharmacology 20060801
Title: [Action of AMP579 and adenosine on potassium or sodium ionic channels in isolated rat and guinea pig ventricular myocytes].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060801
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Involvement of adenosine A1 and A2A receptors in (-)-linalool-induced antinociception.
Journal: Life sciences 20060418
Title: Involvement of adenosine in the effect of fluoxetine on isolated guinea-pig atria.
Journal: Pharmacological research 20060101
Title: Adenosine receptor antagonists intensify the benzodiazepine withdrawal signs in mice.
Journal: Pharmacological reports : PR 20060101
Title: Lumenal adenosine and AMP rapidly increase glucose transport by intact small intestine.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20051201
Title: Vasoconstrictor and vasodilator effects of adenosine in the mouse kidney due to preferential activation of A1 or A2 adenosine receptors.
Journal: The Journal of pharmacology and experimental therapeutics 20051201
Title: Effects of diadenosine polyphosphates on glomerular volume.
Journal: British journal of pharmacology 20050401
Title: Mechanism of vasodilation to adenosine in coronary arterioles from patients with heart disease.
Journal: American journal of physiology. Heart and circulatory physiology 20050401
Title: Adenosine receptor ligands and dizocilpine-induced antinociception in mice.
Journal: The International journal of neuroscience 20050401
Title: GABA release modified by adenosine receptors in mouse hippocampal slices under normal and ischemic conditions.
Journal: Neurochemical research 20050401
Title: Mapping interactions between dopamine and adenosine A2a receptors using pharmacologic MRI.
Journal: Synapse (New York, N.Y.) 20050201
Title: Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes.
Journal: Neuroscience research 20050101
Title: Participation of adenosine system in the ketamine-induced motor activity in mice.
Journal: Pharmacological reports : PR 20050101
Title: Modulation of seizures and synaptic plasticity by adenosinergic receptors in an experimental model of temporal lobe epilepsy induced by pilocarpine in rats.
Journal: Epilepsia 20050101
Title: Tetanic depression is overcome by tonic adenosine A(2A) receptor facilitation of L-type Ca(2+) influx into rat motor nerve terminals.
Journal: The Journal of physiology 20041001
Title: The anticonvulsant action of propofol on epileptiform activity in rat hippocampal slices.
Journal: Anesthesia and analgesia 20041001
Title: Adenosine A1-receptor modulation of glutamate-induced calcium influx in rat retinal ganglion cells.
Journal: Investigative ophthalmology & visual science 20041001
Title: P2X receptor activation elicits transporter-mediated noradrenaline release from rat hippocampal slices.
Journal: The Journal of pharmacology and experimental therapeutics 20040901
Title: Ethanol operant self-administration in rats is regulated by adenosine A2 receptors.
Journal: Alcoholism, clinical and experimental research 20040901
Title: A putative osmoreceptor system that controls neutrophil function through the release of ATP, its conversion to adenosine, and activation of A2 adenosine and P2 receptors.
Journal: Journal of leukocyte biology 20040701
Title: Mechanism of inhibitory effect of citalopram on isolated guinea-pig atria in relation to adenosine receptor.
Journal: Human psychopharmacology 20040701
Title: Roles of adenosine receptors in the regulation of kainic acid-induced neurotoxic responses in mice.
Journal: Brain research. Molecular brain research 20040618
Title: Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase.
Journal: Biochemical pharmacology 20040515
Title: The role of intraspinal adenosine A1 receptors in sympathetic regulation.
Journal: European journal of pharmacology 20040510
Title: [Role of adenosine in intraocular pressure].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040401
Title: Effects of 2-alkynyladenosine derivatives on intraocular pressure in rabbits.
Journal: European journal of pharmacology 20040223
Title: Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20031201
Title: Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031126
Title: Adenosine kinase inhibitors. 3. Synthesis, SAR, and antiinflammatory activity of a series of l-lyxofuranosyl nucleosides.
Journal: Journal of medicinal chemistry 20031023
Title: Hypersensitivity of pulmonary C fibers induced by adenosine in anesthetized rats.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20030901
Title: Polydeoxyribonucleotide (PDRN) promotes human osteoblast proliferation: a new proposal for bone tissue repair.
Journal: Life sciences 20030829
Title: Modification of cardiovascular response of posterior hypothalamic adenosine A(2) receptor stimulation by adenylate cylase, guanylate cyclase and by K(ATP) channel blockade in anesthetized rats.
Journal: Neuroscience letters 20030619
Title: Antinociceptive mechanisms of orally administered decursinol in the mouse.
Journal: Life sciences 20030613
Title: Intraspinal adenosine induces spinal cord norepinephrine release in spinal nerve-ligated rats but not in normal or sham controls.
Journal: Anesthesiology 20030601
Title: Adenosine A1 receptor activation reduces myocardial reperfusion effects on intrinsic cardiac nervous system.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030501
Title: Endogenous adenosine prevents post-tetanic release facilitation mediated by alpha3beta2 nicotinic autoreceptors.
Journal: European journal of pharmacology 20030319
Title: Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.
Journal: European journal of pharmacology 20030124
Title: Cross-talk among noradrenaline, adenosine and protein kinase C in the mechanisms of ischemic preconditioning in rabbits.
Journal: Journal of cardiovascular pharmacology 20030101
Title: Synthesis and evaluation of no-carrier-added 8-cyclopentyl-3-(3-[(18)F]fluoropropyl)-1-propylxanthine ([(18)F]CPFPX): a potent and selective A(1)-adenosine receptor antagonist for in vivo imaging.
Journal: Journal of medicinal chemistry 20021107
Title: Comparison of the ability of adenosine kinase inhibitors and adenosine receptor agonists to attenuate thermal hyperalgesia and reduce motor performance in rats.
Journal: Pharmacology, biochemistry, and behavior 20021001
Title: Actions of specific adenosine receptor A1 and A2 agonists and antagonists in recovery of phrenic motor output following upper cervical spinal cord injury in adult rats.
Journal: Clinical and experimental pharmacology & physiology 20021001
Title: Glucose-induced islet blood flow increase in rats: interaction between nervous and metabolic mediators.
Journal: American journal of physiology. Endocrinology and metabolism 20020901
Title: Role of extracellular ATP metabolism in regulation of platelet reactivity.
Journal: The Journal of laboratory and clinical medicine 20020901
Title: Protective effect of resveratrol against pentylenetetrazole-induced seizures and its modulation by an adenosinergic system.
Journal: Pharmacology 20020701
Title: Adenosine and purine nucleosides protect rat primary astrocytes from peroxynitrite-potentiated, glucose deprivation-induced death: preservation of intracellular ATP level.
Journal: Experimental neurology 20020701
Title: Inhibition of vaccinia virus replication by adenosine in BSC-40 cells: involvement of A(2) receptor-mediated PKA activation.
Journal: Archives of virology 20020701
Title: The involvement of nitric oxide on the adenosine A(2) receptor-induced cardiovascular inhibitory responses in the posterior hypothalamus of rats.
Journal: Neuroscience letters 20020621
Title: Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.
Journal: The American journal of pathology 20020601
Title: Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
Journal: Journal of medicinal chemistry 20020523
Title: Adenosine acts through an A3 receptor to prevent the induction of murine anti-CD3-activated killer T cells.
Journal: International journal of cancer 20020520
Title: Spinal noradrenergic activation mediates allodynia reduction from an allosteric adenosine modulator in a rat model of neuropathic pain.
Journal: Pain 20020501
Title: Adenosine inhibits calcium channel currents via A1 receptors on salamander retinal ganglion cells in a mini-slice preparation.
Journal: Journal of neurochemistry 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Dopaminergic mechanism for caffeine-produced cocaine seeking in rats.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020401
Title: Involvement of adenosine A2 receptors in the changes of tissue factor-dependent coagulant activity induced by polymorphonuclear leukocytes in endothelial cells.
Journal: Japanese journal of pharmacology 20020401
Title: Activation of adenosine A2a receptor pathway reduces leukocyte infiltration but enhances edema formation in rat caerulein pancreatitis.
Journal: Pancreas 20020101
Title: Adenosine receptor ligands and cocaine in conditioned place preference (CPP) test in rats.
Journal: Polish journal of pharmacology 20020101
Title: Cocaine-induced hyperactivity is more influenced by adenosine receptor agonists than amphetamine-induced hyperactivity.
Journal: Polish journal of pharmacology 20020101
Title: Regulation of K(+) current in human airway epithelial cells by exogenous and autocrine adenosine.
Journal: American journal of physiology. Cell physiology 20011201
Title: Adenosine modulates Mg(2+) uptake in distal convoluted tubule cells via A(1) and A(2) purinoceptors.
Journal: American journal of physiology. Renal physiology 20011201
Title: Evidence for the presence of A(1) adenosine receptors in the aorta of spontaneously hypertensive rats.
Journal: British journal of pharmacology 20011201
Title: Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidil.
Journal: The Journal of investigative dermatology 20011201
Title: In vivo effects of adenosine A(2) receptor agonist and antagonist on neuronal and astrocytic intermediary metabolism studied with ex vivo (13)C MR spectroscopy.
Journal: Journal of neurochemistry 20011101
Title: A novel analgesic compound OT-7100 attenuates nociceptive responses in animal models of inflammatory and neuropathic hyperalgesia: a possible involvement of adenosinergic anti-nociception.
Journal: Japanese journal of pharmacology 20011101
Title: Adenosine A(2a) receptor antagonists: potential therapeutic and neuroprotective effects in Parkinson's disease.
Journal: Neurotoxicity research 20011101
Title: Role of adenosine in renal protection induced by a brief episode of ischemic preconditioning in rats.
Journal: Japanese journal of pharmacology 20011001
Title: Methotrexate suppresses NF-kappaB activation through inhibition of IkappaBalpha phosphorylation and degradation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010901
Title: The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells.
Journal: British journal of pharmacology 20010901
Title: Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
Journal: British journal of pharmacology 20010901
Title: Synergism between A(2A)-adenosine receptor activation and vasoactive intestinal peptide to facilitate [3H]-acetylcholine release from the rat motor nerve terminals.
Journal: Neuroscience letters 20010824
Title: Adenosine A(1) receptors mediate plasma exudation from the oral mucosa.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010801
Title: Withdrawal and bidirectional cross-withdrawal responses in rats treated with adenosine agonists and morphine.
Journal: Life sciences 20010706
Title: Sparks and puffs in oligodendrocyte progenitors: cross talk between ryanodine receptors and inositol trisphosphate receptors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601
Title: Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010515
Title: Adenosine inhibits neutrophil vascular endothelial growth factor release and transendothelial migration via A2B receptor activation.
Journal: Shock (Augusta, Ga.) 20010401
Title: Adenosine receptor-adenylate cyclase system in the trout testis: involvement in the regulation of germ cell proliferation.
Journal: Molecular reproduction and development 20010301
Title: Müller cell Ca2+ waves evoked by purinergic receptor agonists in slices of rat retina.
Journal: Journal of neurophysiology 20010201
Title: Signal pathway involved in the development of hypoxic preconditioning in rat hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20010101
Title: Efferent arteriole tubuloglomerular feedback in the renal nephron.
Journal: Kidney international 20010101
Title: Protection by aspirin of indomethacin-induced small intestinal damage in rats: mediation by salicylic acid.
Journal: Journal of physiology, Paris 20010101
Title: Effect of adenosine A1 and A2 receptor stimulation on hypoxia-induced convulsions in adult mice.
Journal: Polish journal of pharmacology 20010101
Title: Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20001001
Title: Evidence against a major role of adenosine in oxygen-dependent regulation of erythropoietin in rats.
Journal: Kidney international 19970801
Title: Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.
Journal: European journal of pharmacology 19970611
Title: Involvement of spinal adenosine A1 and A2 receptors in fentanyl-induced muscular rigidity in the rat.
Journal: Neuroscience letters 19970321
Title: Haloperidol-induced catalepsy is influenced by adenosine receptor antagonists.
Journal: Polish journal of pharmacology 19970101
Title: Adenosine antagonists potentiate D2 dopamine-dependent activation of Fos in the striatopallidal pathway.
Journal: Neuroscience 19951001
