Home Amines 155-41-9
155-41-9,MFCD00078560
Catalog No.:AA003RFI

155-41-9 | Methscopolamine bromide

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500mg
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1g
>98.0%(T)(HPLC)
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003RFI
Chemical Name:
Methscopolamine bromide
CAS Number:
155-41-9
Molecular Formula:
C18H24BrNO4
Molecular Weight:
398.2915
MDL Number:
MFCD00078560
SMILES:
OC[C@H](c1ccccc1)C(=O)O[C@@H]1C[C@@H]2[C@@H]3[C@H]([C@H](C1)[N+]2(C)C)O3.[Br-]
Properties
Properties
 
Form:
Solid  
MP:
>215ºC (dec.)  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
454  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  

Literature

Title: Purification, characterization and anticancer activity of a polysaccharide from Panax ginseng.

Journal: International journal of biological macromolecules 20121201

Title: Two seizure-onset types reveal specific patterns of high-frequency oscillations in a model of temporal lobe epilepsy.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120919

Title: Regional quantification of muscarinic acetylcholine receptors and β-adrenoceptors in human airways.

Journal: British journal of pharmacology 20120701

Title: Reversal of scopolamine-induced disruption of prepulse inhibition by clozapine in mice.

Journal: Pharmacology, biochemistry, and behavior 20120301

Title: The context preexposure facilitation effect in mice: a dose-response analysis of pretraining scopolamine administration.

Journal: Behavioural brain research 20111120

Title: Influence of tissue integrity on pharmacological phenotypes of muscarinic acetylcholine receptors in the rat cerebral cortex.

Journal: The Journal of pharmacology and experimental therapeutics 20111001

Title: Intracellular distribution of functional M(1) -muscarinic acetylcholine receptors in N1E-115 neuroblastoma cells.

Journal: Journal of neurochemistry 20110901

Title: Characterization of muscarinic receptors in the human bladder mucosa: direct quantification of subtypes using 4-DAMP mustard.

Journal: Urology 20110901

Title: Negative cooperativity in binding of muscarinic receptor agonists and GDP as a measure of agonist efficacy.

Journal: British journal of pharmacology 20110301

Title: Sensorimotor gating and vigilance-dependent choice accuracy: a within-subject correlative analysis in wild-type C57BL/6 mice.

Journal: Behavioural brain research 20110202

Title: Selective binding of bladder muscarinic receptors in relation to the pharmacokinetics of a novel antimuscarinic agent, imidafenacin, to treat overactive bladder.

Journal: The Journal of pharmacology and experimental therapeutics 20110201

Title: Subtype differences in pre-coupling of muscarinic acetylcholine receptors.

Journal: PloS one 20110101

Title: Mice lacking Melanin Concentrating Hormone 1 receptor are resistant to seizures.

Journal: Neuroscience letters 20101029

Title: Muscarinic receptors and their mRNAs in type 2 Goto-Kakizaki diabetic rat prostate.

Journal: The Prostate 20101001

Title: Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis.

Journal: Urology 20101001

Title: Investigating the interaction of McN-A-343 with the M muscarinic receptor using its nitrogen mustard derivative and ACh mustard.

Journal: British journal of pharmacology 20100701

Title: Pharmacological magnetic resonance imaging of muscarinic acetylcholine receptor activation in rat brain.

Journal: Neuropharmacology 20100601

Title: Detection of novel functional selectivity at M3 muscarinic acetylcholine receptors using a Saccharomyces cerevisiae platform.

Journal: ACS chemical biology 20100416

Title: Investigating the interaction of McN-A-343 with the M2 muscarinic receptor using its nitrogen mustard derivative.

Journal: Biochemical pharmacology 20100401

Title: Molecular mechanisms of action and in vivo validation of an M4 muscarinic acetylcholine receptor allosteric modulator with potential antipsychotic properties.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100301

Title: Acute ethanol exposure elevates muscarinic tone in the septohippocampal system.

Journal: Journal of neurophysiology 20100101

Title: Assessment of novel muscarinic acetylcholine receptors in rat cerebral cortex by a tissue segment binding method.

Journal: Journal of pharmacological sciences 20100101

Title: Exploring the mechanism of agonist efficacy: a relationship between efficacy and agonist dissociation rate at the muscarinic M3 receptor.

Journal: Molecular pharmacology 20090901

Title: Weak toxin WTX from Naja kaouthia cobra venom interacts with both nicotinic and muscarinic acetylcholine receptors.

Journal: The FEBS journal 20090901

Title: Role of acetylcholine in negative patterning in turtles (Chrysemys picta).

Journal: Behavioral neuroscience 20090801

Title: Immediate and delayed consequences of xanomeline wash-resistant binding at the M3 muscarinic receptor.

Journal: Neurochemical research 20090601

Title: Mechanisms of M3 muscarinic receptor regulation by wash-resistant xanomeline binding.

Journal: Pharmacology 20090501

Title: Scopolamine induced deficits in a battery of rat cognitive tests: comparisons of sensitivity and specificity.

Journal: Behavioural pharmacology 20090501

Title: Pharmacologically relevant receptor binding characteristics and 5alpha-reductase inhibitory activity of free Fatty acids contained in saw palmetto extract.

Journal: Biological & pharmaceutical bulletin 20090401

Title: Quantitative analysis of the loss of muscarinic receptors in various peripheral tissues in M1-M5 receptor single knockout mice.

Journal: British journal of pharmacology 20090401

Title: Membrane cholesterol content influences binding properties of muscarinic M2 receptors and differentially impacts activation of second messenger pathways.

Journal: European journal of pharmacology 20090315

Title: Nucleus accumbens acetylcholine and food intake: decreased muscarinic tone reduces feeding but not food-seeking.

Journal: Behavioural brain research 20090302

Title: Divergence of allosteric effects of rapacuronium on binding and function of muscarinic receptors.

Journal: BMC pharmacology 20090101

Title: Different interactions between MT7 toxin and the human muscarinic M1 receptor in its free and N-methylscopolamine-occupied states.

Journal: Molecular pharmacology 20081201

Title: Combined blockade of serotonergic and muscarinic transmission disrupts the anterior thalamic head direction signal.

Journal: Behavioral neuroscience 20081201

Title: G protein coupling and signaling pathway activation by m1 muscarinic acetylcholine receptor orthosteric and allosteric agonists.

Journal: The Journal of pharmacology and experimental therapeutics 20081101

Title: Use of acetylcholine mustard to study allosteric interactions at the M(2) muscarinic receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20081101

Title: Binding of orthosteric ligands to the allosteric site of the M(2) muscarinic cholinergic receptor.

Journal: Molecular pharmacology 20080901

Title: Two-state models and the analysis of the allosteric effect of gallamine at the M2 muscarinic receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20080601

Title: The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions.

Journal: The Journal of pharmacology and experimental therapeutics 20080601

Title: Diphenidol-related diamines as novel muscarinic M4 receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20080501

Title: Bronchodilatory effects of S-isopetasin, an antimuscarinic sesquiterpene of Petasites formosanus, on obstructive airway hyperresponsiveness.

Journal: European journal of pharmacology 20080428

Title: Impairment of muscarinic transmission in transgenic APPswe/PS1dE9 mice.

Journal: Neurobiology of aging 20080301

Title: Assessment of muscarinic receptor subtypes in human and rat lower urinary tract by tissue segment binding assay.

Journal: Journal of pharmacological sciences 20080201

Title: Cysteine pairs in the third intracellular loop of the muscarinic m1 acetylcholine receptor play a role in agonist-induced internalization.

Journal: The Journal of pharmacology and experimental therapeutics 20080101

Title: Activation of 5-HT(1A) receptors attenuates tachycardia induced by restraint stress in rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080101

Title: Effects of chlorpyrifos oxon on M2 muscarinic receptor internalization in different cell types.

Journal: Journal of toxicology and environmental health. Part A 20080101

Title: Oxotremorine-induced hypothermia as a method for evaluating long-term neuronal changes following poisoning by cholinesterase inhibitors in rats.

Journal: Toxicology 20071205

Title: Long-term changes in the muscarinic M1 receptor induced by instantaneous formation of wash-resistant xanomeline-receptor complex.

Journal: The Journal of pharmacology and experimental therapeutics 20071201

Title: Caveolae facilitate muscarinic receptor-mediated intracellular Ca2+ mobilization and contraction in airway smooth muscle.

Journal: American journal of physiology. Lung cellular and molecular physiology 20071201

Title: Muscarinic receptor antagonism of the nucleus accumbens core causes avoidance to flavor and spatial cues.

Journal: Behavioral neuroscience 20071201

Title: Functional analysis of transmembrane domain 2 of the M1 muscarinic acetylcholine receptor.

Journal: The Journal of biological chemistry 20071102

Title: Allosteric interaction of the neuromuscular blockers vecuronium and pancuronium with recombinant human muscarinic M2 receptors.

Journal: European journal of pharmacology 20070813

Title: A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptor.

Journal: Molecular pharmacology 20070801

Title: Hemodynamic consequences of chronic parasympathetic blockade with a peripheral muscarinic antagonist.

Journal: American journal of physiology. Heart and circulatory physiology 20070801

Title: Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors.

Journal: Molecular pharmacology 20070801

Title: Cholesterol as a determinant of cooperativity in the M2 muscarinic cholinergic receptor.

Journal: Biochemical pharmacology 20070715

Title: Recovery of oligomers and cooperativity when monomers of the M2 muscarinic cholinergic receptor are reconstituted into phospholipid vesicles.

Journal: Biochemistry 20070703

Title: Cytokine modulation of muscarinic receptors in the murine intestine.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701

Title: Wash-resistantly bound xanomeline inhibits acetylcholine release by persistent activation of presynaptic M(2) and M(4) muscarinic receptors in rat brain.

Journal: The Journal of pharmacology and experimental therapeutics 20070701

Title: Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain.

Journal: Life sciences 20070606

Title: A non-spatial, stimulus-comparison working memory task in rats and disruption by scopolamine.

Journal: Neuroscience 20070330

Title: Mutational disruption of a conserved disulfide bond in muscarinic acetylcholine receptors attenuates positive homotropic cooperativity between multiple allosteric sites and has subtype-dependent effects on the affinities of muscarinic allosteric ligands.

Journal: Molecular pharmacology 20070301

Title: Opposing effects on muscarinic acetylcholine receptors in the piriform cortex of odor-trained rats.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20070301

Title: Urodynamics and bladder muscarinic receptors in rats with cerebral infarction and bladder outlet obstruction.

Journal: Neuroscience letters 20070227

Title: Segment-dependent expression of muscarinic acetylcholine receptors and G-protein coupling in the equine respiratory tract.

Journal: Veterinary research communications 20070201

Title: Parasympathetic dysfunction is associated with baroreflex and chemoreflex impairment in streptozotocin-induced diabetes in rats.

Journal: Autonomic neuroscience : basic & clinical 20070130

Title: Autonomic control of bronchial blood flow and airway dimensions during strenuous exercise in sheep.

Journal: Pulmonary pharmacology & therapeutics 20070101

Title: Effects of graded exercise on bronchial blood flow and airway dimensions in sheep.

Journal: Pulmonary pharmacology & therapeutics 20070101

Title: Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents.

Journal: Biological & pharmaceutical bulletin 20070101

Title: Long-term wash-resistant effects of brief interaction of xanomeline at the M1 muscarinic receptor.

Journal: Neuroscience letters 20061213

Title: Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20061101

Title: Migrastatin acts as a muscarinic acetylcholine receptor antagonist.

Journal: The Journal of antibiotics 20061101

Title: Differences in kinetics of xanomeline binding and selectivity of activation of G proteins at M(1) and M(2) muscarinic acetylcholine receptors.

Journal: Molecular pharmacology 20060801

Title: Enhancing effects of nicotine and impairing effects of scopolamine on distinct aspects of performance in computerized attention and working memory tasks in marmoset monkeys.

Journal: Neuropharmacology 20060801

Title: Interaction studies of multiple binding sites on m4 muscarinic acetylcholine receptors.

Journal: Molecular pharmacology 20060801

Title: Quantifying the association and dissociation rates of unlabelled antagonists at the muscarinic M3 receptor.

Journal: British journal of pharmacology 20060801

Title: Allosteric interactions with muscarinic acetylcholine receptors: complex role of the conserved tryptophan M2422Trp in a critical cluster of amino acids for baseline affinity, subtype selectivity, and cooperativity.

Journal: Molecular pharmacology 20060701

Title: Development of a rat pilocarpine model of seizure/status epilepticus that mimics chemical warfare nerve agent exposure.

Journal: Toxicology and industrial health 20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Function-specific blockage of M(1) and M(3) muscarinic acetylcholine receptors by VX and echothiophate.

Journal: Brain research 20060426

Title: Muscarinic allosteric modulators: atypical structure-activity-relationships in bispyridinium-type compounds.

Journal: Archiv der Pharmazie 20060401

Title: M1 muscarinic receptors contribute to, whereas M4 receptors inhibit, dopamine D1 receptor-induced [3H]-cyclic AMP accumulation in rat striatal slices.

Journal: Neurochemical research 20060401

Title: A G protein gamma subunit peptide stabilizes a novel muscarinic receptor state.

Journal: Biochemical and biophysical research communications 20060324

Title: Advantages for transdermal over oral oxybutynin to treat overactive bladder: Muscarinic receptor binding, plasma drug concentration, and salivary secretion.

Journal: The Journal of pharmacology and experimental therapeutics 20060301

Title: Effects of rat sinoaortic denervation on the vagal responsiveness and expression of muscarinic acetylcholine receptors.

Journal: Journal of cardiovascular pharmacology 20060301

Title: Soft quaternary anticholinergics: comprehensive quantitative structure-activity relationship (QSAR) with a linearized biexponential (LinBiExp) model.

Journal: Journal of medicinal chemistry 20060209

Title: Effects of biasing the location of stimulus presentation, and the muscarinic cholinergic receptor antagonist scopolamine, on performance of a 5-choice serial reaction time attention task in rats.

Journal: Behavioural pharmacology 20060201

Title: Differential effects of cocaine-induced seizures and lethality on M(1)-like muscarinic and dopaminergic D (1)- and D (2)-like binding receptors in mice brain.

Journal: Cellular and molecular neurobiology 20060201

Title: Probing the molecular mechanism of interaction between 4-n-butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the muscarinic M(1) receptor: direct pharmacological evidence that AC-42 is an allosteric agonist.

Journal: Molecular pharmacology 20060101

Title: Effects of cochlear ablation on muscarinic acetylcholine receptor binding in the rat cochlear nucleus.

Journal: Journal of neuroscience research 20060101

Title: Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060101

Title: Determination of phenylephrine hydrochloride, chlorpheniramine maleate, and methscopolamine nitrate in tablets or capsules by liquid chromatography with two UV absorbance detectors in series.

Journal: Journal of AOAC International 20060101

Title: Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors.

Journal: Journal of molecular neuroscience : MN 20060101

Title: Rapacuronium augments acetylcholine-induced bronchoconstriction via positive allosteric interactions at the M3 muscarinic receptor.

Journal: Anesthesiology 20051201

Title: Single unit activity in the medial prefrontal cortex during Pavlovian heart rate conditioning: Effects of peripheral autonomic blockade.

Journal: Neurobiology of learning and memory 20051101

Title: In vitro evidence and age-related changes for nicotinic but not muscarinic acetylcholine receptors in the central nervous system of Sepia officinalis.

Journal: Neuroscience letters 20051028

Title: Persistent binding and functional antagonism by xanomeline at the muscarinic M5 receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20051001

Title: Pilocarpine-induced status epilepticus: monoamine level, muscarinic and dopaminergic receptors alterations in striatum of young rats.

Journal: Neuroscience letters 20050701

Title: Antiepileptic effect of acylpolyaminetoxin JSTX-3 on rat hippocampal CA1 neurons in vitro.

Journal: Brain research 20050628

Title: Blood-brain barrier and electromagnetic fields: effects of scopolamine methylbromide on working memory after whole-body exposure to 2.45 GHz microwaves in rats.

Journal: Behavioural brain research 20050620

Title: In vivo demonstration of muscarinic receptor binding activity of N-desethyl-oxybutynin, active metabolite of oxybutynin.

Journal: Life sciences 20050408

Title: Effects of saw palmetto extract on micturition reflex of rats and its autonomic receptor binding activity.

Journal: The Journal of urology 20050401

Title: Cremastrine, a pyrrolizidine alkaloid from Cremastra appendiculata.

Journal: Journal of natural products 20050401

Title: Muscarinic allosteric enhancers of ligand binding: pivotal pharmacophoric elements in hexamethonio-type agents.

Journal: Journal of medicinal chemistry 20050324

Title: Quantitative analysis of binding parameters of [3H]N-methylscopolamine in central nervous system of muscarinic acetylcholine receptor knockout mice.

Journal: Brain research. Molecular brain research 20050105

Title: Anticonvulsant activity of ginseng on seizures induced by chemical convulsants.

Journal: Epilepsia 20050101

Title: Inhibition of ligand binding to G protein-coupled receptors by arachidonic acid.

Journal: Journal of molecular neuroscience : MN 20050101

Title: Cholinergic stimulation of salivary secretion studied with M1 and M3 muscarinic receptor single- and double-knockout mice.

Journal: Molecular pharmacology 20040801

Title: Action of the muscarinic toxin MT7 on agonist-bound muscarinic M1 receptors.

Journal: European journal of pharmacology 20040308

Title: Application of a kinetic model to the apparently complex behavior of negative and positive allosteric modulators of muscarinic acetylcholine receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20040301

Title: Cocaine treatment causes early and long-lasting changes in muscarinic and dopaminergic receptors.

Journal: Cellular and molecular neurobiology 20040201

Title: Vinburnine decelerates [3H]N-methylscopolamine binding to recombinant human muscarinic M1-M4 acetylcholine receptors.

Journal: European journal of pharmacology 20040112

Title: Differential profiles of cholinesterase inhibition and neurobehavioral effects in rats exposed to fenamiphos or profenofos.

Journal: Neurotoxicology and teratology 20040101

Title: Site of action of the general anesthetic propofol in muscarinic M1 receptor-mediated signal transduction.

Journal: The Journal of pharmacology and experimental therapeutics 20031201

Title: Carbamoylcholine homologs: novel and potent agonists at neuronal nicotinic acetylcholine receptors.

Journal: Molecular pharmacology 20031001

Title: N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits ligand binding to certain G protein-coupled receptors.

Journal: European journal of pharmacology 20030801

Title: Contribution of lateral substituents in symmetrical and non-symmetrical heptane-bisammonio compounds to the allosteric stabilization of N-methylscopolamine binding to muscarinic M2 receptors.

Journal: Archiv der Pharmazie 20030801

Title: Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors.

Journal: Molecular pharmacology 20030701

Title: Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors.

Journal: Molecular pharmacology 20030701

Title: Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors.

Journal: Bioorganic & medicinal chemistry 20030612

Title: An unusual form of the association binding kinetics of N-[3H]methylscopolamine to the split muscarinic M2trunk/M2tail receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20030501

Title: Comparison of the pharmacological antagonism of M2 and M3 muscarinic receptors expressed in isolation and in combination.

Journal: Biochemical pharmacology 20030415

Title: Cooperative interactions at M2 muscarinic acetylcholine receptors: structure/activity relationships in stepwise shortened bispyridinium- and bis(ammonio)alkane-type allosteric modulators.

Journal: Neurochemical research 20030401

Title: Intravenous atropine treatment in infantile hypertrophic pyloric stenosis.

Journal: Archives of disease in childhood 20030101

Title: Selective interaction of bile acids with muscarinic receptors: a case of molecular mimicry.

Journal: European journal of pharmacology 20021220

Title: Interaction of intravenous anesthetics with recombinant human M1-M3 muscarinic receptors expressed in chinese hamster ovary cells.

Journal: Anesthesia and analgesia 20021201

Title: Muscarinic receptors in equine airways.

Journal: Veterinary research communications 20021201

Title: Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice.

Journal: Molecular pharmacology 20021101

Title: Effects of N-ethylmaleimide on conformational equilibria in purified cardiac muscarinic receptors.

Journal: The Journal of biological chemistry 20020927

Title: Expression of peripheral blood lymphocyte muscarinic cholinergic receptor subtypes in airway hyperresponsiveness.

Journal: Journal of neuroimmunology 20020801

Title: Use of an in situ disulfide cross-linking strategy to map proximities between amino acid residues in transmembrane domains I and VII of the M3 muscarinic acetylcholine receptor.

Journal: Biochemistry 20020618

Title: Allosteric modulation by persistent binding of xanomeline of the interaction of competitive ligands with the M1 muscarinic acetylcholine receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20020601

Title: Cooperativity and oligomeric status of cardiac muscarinic cholinergic receptors.

Journal: Biochemistry 20020430

Title: Attenuating effects of melatonin on pilocarpine-induced seizures in rats.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020401

Title: Substituted pentacyclic carbazolones as novel muscarinic allosteric agents: synthesis and structure-affinity and cooperativity relationships.

Journal: Journal of medicinal chemistry 20020314

Title: Peripheral cholinergic pathway modulates hyperthermia induced by stress in rats exposed to open-field stress.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020201

Title: Muscarinic cholinergic receptor blockade impairs free fatty acid mobilization during fasting in pigeons (Columba livia).

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020201

Title: Central anticholinergics to treat nerve-agent poisoning.

Journal: Lancet (London, England) 20020119

Title: A new enzymic method for the isolation and culture of human bladder body smooth muscle cells.

Journal: Neurourology and urodynamics 20020101

Title: Heart rate changes accompanying jaw movement Pavlovian conditioning in rabbits: concomitant blood pressure adjustments and effects of peripheral autonomic blockade.

Journal: Integrative physiological and behavioral science : the official journal of the Pavlovian Society 20020101

Title: Peripheral blood lymphocytes muscarinic cholinergic receptor subtypes in Alzheimer's disease: a marker of cholinergic dysfunction?

Journal: Journal of neuroimmunology 20011203

Title: Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors.

Journal: Brain research 20011005

Title: Apparent capacity of cardiac muscarinic receptors for different radiolabeled antagonists.

Journal: Biochemical pharmacology 20011001

Title: Intestinal serotonin acts as paracrine substance to mediate pancreatic secretion stimulated by luminal factors.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20011001

Title: Changes of cooperativity between N-methylscopolamine and allosteric modulators alcuronium and gallamine induced by mutations of external loops of muscarinic M(3) receptors.

Journal: Molecular pharmacology 20011001

Title: Identification of muscarinic receptor subtypes of cultured smooth muscle cells and tissue of human bladder body.

Journal: International journal of urology : official journal of the Japanese Urological Association 20011001

Title: Substance P and its transglutaminase-synthesized spermine derivative elicit yawning behavior via nitric oxide in rats.

Journal: Peptides 20010901

Title: Effects of molsidomine on scopolamine-induced amnesia and hypermotility in the rat.

Journal: European journal of pharmacology 20010831

Title: Influence of benzodiazepine binding site ligands on fear-conditioned contextual memory.

Journal: European journal of pharmacology 20010824

Title: Muscarinic allosteric modulation: M2/M3 subtype selectivity of gallamine is independent of G-protein coupling specificity.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010801

Title: Peripheral versus central muscarinic effects on blood pressure, cardiac contractility, heart rate, and body temperature in the rat monitored by radiotelemetry.

Journal: Pharmacology & toxicology 20010701

Title: Activity-induced expression of common reference genes in individual cns neurons.

Journal: Laboratory investigation; a journal of technical methods and pathology 20010601

Title: Interaction of edrophonium with muscarinic acetylcholine M2 and M3 receptors.

Journal: Anesthesiology 20010501

Title: Hexamethonium-type allosteric modulators of the muscarinic receptors bearing lateral dibenzazepine moieties.

Journal: Archiv der Pharmazie 20010401

Title: Interactions between allosteric modulators and 4-DAMP and other antagonists at muscarinic receptors: potential significance of the distance between the N and carboxyl C atoms in the molecules of antagonists.

Journal: Neurochemical research 20010401

Title: The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria.

Journal: European journal of pharmacology 20010330

Title: Dual effects of muscarinic M(2) acetylcholine receptors on the synthesis of cyclic AMP in CHO cells: dependence on time, receptor density and receptor agonists.

Journal: British journal of pharmacology 20010301

Title: Kinetic evidence for different mechanisms of interaction of black mamba toxins MT alpha and MT beta with muscarinic receptors.

Journal: Toxicon : official journal of the International Society on Toxinology 20010101

Title: Lateral parabrachial lesions impair taste aversion learning induced by blood-borne visceral stimuli.

Journal: Pharmacology, biochemistry, and behavior 20010101

Title: Allosteric interactions of staurosporine and other indolocarbazoles with N-[methyl-(3)H]scopolamine and acetylcholine at muscarinic receptor subtypes: identification of a second allosteric site.

Journal: Molecular pharmacology 20000701

Title: Selectivity profile of muscarinic toxin 3 in functional assays of cloned and native receptors.

Journal: The Journal of pharmacology and experimental therapeutics 19990101

Title: Allosteric effects of four stereoisomers of a fused indole ring system with 3H-N-methylscopolamine and acetylcholine at M1-M4 muscarinic receptors.

Journal: Life sciences 19990101

Title: On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor.

Journal: Molecular pharmacology 19980601

Title: Central cardiovascular effects of tacrine in the conscious dog: a role for catecholamines and vasopressin release.

Journal: European journal of pharmacology 19980508

Title: Subtype-selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: radioligand binding studies.

Journal: Molecular pharmacology 19980301

Title: Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors.

Journal: Molecular pharmacology 19970701

Title: Selective labeling and localization of the M4 (m4) muscarinic receptor subtype.

Journal: Molecular pharmacology 19941201

Title: Binding profile of the selective muscarinic receptor antagonist tripitramine.

Journal: European journal of pharmacology 19940816

Title: Binding and functional properties of hexocyclium and sila-hexocyclium derivatives to muscarinic receptor subtypes.

Journal: British journal of pharmacology 19940601

Title: Time gradient for post-test vulnerability to scopolamine-induced amnesia following the initial acquisition session of a spatial reference memory task in mice.

Journal: Behavioral and neural biology 19930901

Title: Application of transfected cell lines in studies of functional receptor subtype selectivity of muscarinic agonists.

Journal: The Journal of pharmacology and experimental therapeutics 19930701

Title: Carbamazepine-induced neurotoxicity and its prevention by NMDA in cultured cerebellar granule cells.

Journal: Neuroscience letters 19920203

Title: Antagonist binding profiles of five cloned human muscarinic receptor subtypes.

Journal: The Journal of pharmacology and experimental therapeutics 19910201

Title: Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy.

Journal: Neuroscience and biobehavioral reviews 19900101

Title: Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.

Journal: Molecular pharmacology 19890401

Title: CR-1409: a potent inhibitor of cholecystokinin-stimulated amylase release and cholecystokinin binding in rat pancreatic acini.

Journal: Pancreas 19870101

Title: Effects of physostigmine on pulse, blood pressure, and serum epinephrine levels.

Journal: The American journal of psychiatry 19850601

Title: Central cholinergic mechanisms in L-DOPA induced hyperactive urinary bladder of the rat.

Journal: Urological research 19820101

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Tags:155-41-9 Molecular Formula|155-41-9 MDL|155-41-9 SMILES|155-41-9 Methscopolamine bromide