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Home Other Building Blocks 2162-31-4
2162-31-4,MFCD00185588
Catalog No.:AA003UME

2162-31-4 | 2-(Tetrahydro-2h-pyran-2-yloxy)ethanol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
95%
in stock  
$7.00   $5.00
- +
1g
95%
in stock  
$18.00   $13.00
- +
5g
95%
in stock  
$73.00   $51.00
- +
10g
95%
in stock  
$125.00   $88.00
- +
25g
98%
in stock  
$286.00   $200.00
- +
100g
95%
in stock  
$809.00   $567.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003UME
Chemical Name:
2-(Tetrahydro-2h-pyran-2-yloxy)ethanol
CAS Number:
2162-31-4
Molecular Formula:
C7H14O3
Molecular Weight:
146.1843
MDL Number:
MFCD00185588
SMILES:
OCC(C1CCCCO1)O
Properties
Properties
 
BP:
255.3°C at 760 mmHg  
Form:
Liquid  
Refractive Index:
n20/D 1.457  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
84.9  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.3  

Downstream Synthesis Route

[1]Eshghi,Hossein;Shafieyoon,Parvaneh[Phosphorus,SulfurandSiliconandtheRelatedElements,2004,vol.179,#10,p.2149-2152]

[2]Li,Kai;Ran,Li;Yu,Yi-Hua;Tang,Yong[JournalofOrganicChemistry,2004,vol.69,#11,p.3986-3989]

[3]Ravindranath;Ramesh;Das[Synlett,2001,#11,p.1777-1778]

[4]Li,Lingjun;Zhu,Lizhi;Zhang,Xinying;Zhang,Guisheng;Qu,Guirong[CanadianJournalofChemistry,2005,vol.83,#8,p.1120-1123]

[5]Kreibich,Michael;Petrović,Denis;Brückner,Reinhard[JournalofOrganicChemistry,2018,vol.83,#3,p.1116-1133]

[6]He,Tao;Li,Dejin;Sheng,Xia;Zhao,Bin[Macromolecules,2004,vol.37,#9,p.3128-3135]

[7]Vries,ErikF.J.de;Steenwinkel,Pablo;Brussee,Johannes;Kruse,ChrisG.;Gen,Arnevander[JournalofOrganicChemistry,1993,vol.58,#16,p.4315-4325]

[8]Namboodiri,VasudevanV;Varma,RajenderS[TetrahedronLetters,2002,vol.43,#7,p.1143-1146]

[9]Namboodiri,VasudevanV.;Varma,RajenderS.[ChemicalCommunications,2002,#4,p.342-343]

[10]Yue,Xuyi;Taraban,MarcB.;Hyland,LauraL.;Yu,YihuaBruce[JournalofOrganicChemistry,2012,vol.77,#20,p.8879-8887]

[11]Locationinpatent:experimentalpartBeuerle,Florian;Hirsch,Andreas[Chemistry-AEuropeanJournal,2009,vol.15,#30,p.7434-7446]

[12]Hamel,Jean-Denys;Paquin,Jean-François[JournalofFluorineChemistry,2018,vol.216,p.11-23]

[13]Lee,ChungRyul;Lee,SangYeul;Nam,Tae-Gyu[SyntheticCommunications,2014,vol.44,#17,p.2488-2493]

[14]Ihara,Toshihiro;Sato,Yoshinobu;Shimada,Hiroshi;Jyo,Akinori[Nucleosides,nucleotidesandnucleicacids,2008,vol.27,#9,p.1084-1096]

[15]Inouye,Masahiko;Akamatsu,Kaori;Nakazumi,Hiroyuki[JournaloftheAmericanChemicalSociety,1997,vol.119,#39,p.9160-9165]

[16]Lyttle;Satyam;Hocker;Bauer;Caldwell;Hui;Morgan;Mergia;Kauvar[JournalofMedicinalChemistry,1994,vol.37,#10,p.1501-1507]

[17]CurrentPatentAssignee:3-DMATRIX,LTD.-US10835637,2020,B2Locationinpatent:Page/Pagecolumn9-10

[18]CurrentPatentAssignee:FOGHORNTHERAPEUTICSINC-WO2021/155321,2021,A2Locationinpatent:Page/Pagecolumn313

[19]CurrentPatentAssignee:COCRYSTALPHARMA,INC.-WO2016/154241,2016,A1Locationinpatent:Paragraph607;611

[20]Chou,Teh-Chang;Chen,Shing-Yi;Chen,Yie-Hsung[Tetrahedron,2003,vol.59,#50,p.9939-9950]

[21]CurrentPatentAssignee:LONZAGROUPAG-EP2332929,2011,A1Locationinpatent:Page/Pagecolumn23-24

[22]CurrentPatentAssignee:LONZAGROUPAG-WO2011/64300,2011,A1Locationinpatent:Page/Pagecolumn35

[1]Vries,ErikF.J.de;Steenwinkel,Pablo;Brussee,Johannes;Kruse,ChrisG.;Gen,Arnevander[JournalofOrganicChemistry,1993,vol.58,#16,p.4315-4325]

[2]CurrentPatentAssignee:HAMAMATSUPHOTONICSKK-US2015/225368,2015,A1Locationinpatent:Paragraph0109-0111

[3]CurrentPatentAssignee:HAMAMATSUPHOTONICSKK-US2016/256578,2016,A1Locationinpatent:Paragraph0122;0123

[4]Weber,Edwin[LiebigsAnnalenderChemie,1983,#5,p.770-801]

[5]CurrentPatentAssignee:COMMONWEALTHSCIENTIFICANDINDUSTRIALRESEARCHORGANISATION-US2016/75716,2016,A1Locationinpatent:Paragraph0140-0143

[1]Inouye,Masahiko;Akamatsu,Kaori;Nakazumi,Hiroyuki[JournaloftheAmericanChemicalSociety,1997,vol.119,#39,p.9160-9165]

[2]CurrentPatentAssignee:ROCHEHOLDINGAG;ARVINAS-US2019/300521,2019,A1Locationinpatent:Paragraph0728-0729

2-2-(4-Trifluoromethyl-benzyloxy)-ethoxy-tetrahydro-pyran 
  2162-31-4    6140-17-6 

[1]JournalofOrganicChemistry,1998,vol.63,p.4172-4173

[1]CurrentPatentAssignee:LONZAGROUPAG-EP2332929,2011,A1Locationinpatent:Page/Pagecolumn23-24

[2]CurrentPatentAssignee:LONZAGROUPAG-WO2011/64300,2011,A1Locationinpatent:Page/Pagecolumn35

[3]Novak,MarkJ.[BioorganicandMedicinalChemistryLetters,1999,vol.9,#1,p.31-34]

Literature

Title: Versatile and selective synthesis of 'click chemistry' compatible heterobifunctional poly(ethylene glycol)s possessing azide and alkyne functionalities.

Journal: Bioconjugate chemistry 20100217

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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SDS
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