Home Other Building Blocks 500735-47-7
500735-47-7,MFCD06411574
Catalog No.:AA00DJVG

500735-47-7 | OLOMOUCINE II

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$63.00   $44.00
- +
5mg
≥98%
in stock  
$220.00   $154.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DJVG
Chemical Name:
OLOMOUCINE II
CAS Number:
500735-47-7
Molecular Formula:
C19H26N6O2
Molecular Weight:
370.4487
MDL Number:
MFCD06411574
SMILES:
CC[C@@H](Nc1nc(NCc2ccccc2O)c2c(n1)n(cn2)C(C)C)CO
NSC Number:
736738
Properties
Computed Properties
 
Complexity:
454  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.8  

Literature

Title: Transient inhibition of cell proliferation does not compromise self-renewal of mouse embryonic stem cells.

Journal: Experimental cell research 20121001

Title: Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone.

Journal: Pharmacological research 20120301

Title: Cdk2 inhibition prolongs G1 phase progression in mouse embryonic stem cells.

Journal: Stem cells and development 20100201

Title: The inhibitor of cyclin-dependent kinases, olomoucine II, exhibits potent antiviral properties.

Journal: Antiviral chemistry & chemotherapy 20100105

Title: Interactions of olomoucine II with human liver microsomal cytochromes P450.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090601

Title: Functional p53 in cells contributes to the anticancer effect of the cyclin-dependent kinase inhibitor roscovitine.

Journal: Journal of cellular biochemistry 20090601

Title: Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor.

Journal: Cellular and molecular life sciences : CMLS 20050801

Title: Synthesis and biological activity of olomoucine II.

Journal: Bioorganic & medicinal chemistry letters 20021118

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:500735-47-7 Molecular Formula|500735-47-7 MDL|500735-47-7 SMILES|500735-47-7 OLOMOUCINE II