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504-33-6,MFCD00007536
Catalog No.:AA0000UR

504-33-6 | Dl-homocysteic acid

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1g
96%
in stock  
$22.00   $15.00
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5g
96%
in stock  
$77.00   $54.00
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10g
96%
in stock  
$134.00   $94.00
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25g
96%
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$211.00   $148.00
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100g
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$610.00   $427.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0000UR
Chemical Name:
Dl-homocysteic acid
CAS Number:
504-33-6
Molecular Formula:
C4H9NO5S
Molecular Weight:
183.1830
MDL Number:
MFCD00007536
SMILES:
OC(=O)C(CCS(=O)(=O)O)N
Properties
Properties
 
Form:
Solid  
MP:
273 °C  
Refractive Index:
1.5480 (estimate)  
Solubility:
water: soluble50mg/mL, clear to slightly hazy, colorless to yellow  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
227  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-3.6  

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,1984,vol.27,p.600-604

504-33-6   
2-Amino-4-chlorosulfonyl-butyrylchloride 

[1]BioorganicChemistry,1997,vol.25,p.283-296

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Journal: Epilepsia 20030301

Title: Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine.

Journal: Experimental neurology 20030301

Title: Influence of respiratory network drive on phrenic motor output evoked by activation of cat pre-Botzinger complex.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030201

Title: Descending influences from the lateral hypothalamus and amygdala converge onto medullary taste neurons.

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Title: Taste responses of neurons in the hamster solitary nucleus are modulated by the central nucleus of the amygdala.

Journal: Journal of neurophysiology 20021201

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Title: Cerebellar stimulation modulates the intensity of a visceral nociceptive reflex in the rat.

Journal: Experimental brain research 20020901

Title: Sympathoexcitation to intravenous interleukin-1beta is dependent on forebrain neural circuits.

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Title: Stimulation in the rat fastigial nucleus enhances the responses of neurons in the dorsal column nuclei to innocuous stimuli.

Journal: Neuroscience letters 20020712

Title: alpha(2)-Adrenergic receptors in NTS facilitate baroreflex function in adult spontaneously hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology 20020601

Title: Modulation of expiratory motor output evoked by chemical activation of pre-Bötzinger complex in vivo.

Journal: Respiratory physiology & neurobiology 20020601

Title: DL-Homocysteic acid application disrupts calcium homeostasis and induces degeneration of spinal motor neurons in vivo.

Journal: Acta neuropathologica 20020501

Title: Depressor and tachypneic responses to chemical stimulation of the ventral respiratory group are reduced by ablation of neurokinin-1 receptor-expressing neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020501

Title: Role of the medullary raphé in thermoregulatory vasomotor control in rats.

Journal: The Journal of physiology 20020415

Title: Taste responses of neurons of the hamster solitary nucleus are enhanced by lateral hypothalamic stimulation.

Journal: Journal of neurophysiology 20020401

Title: Modulation of gasp frequency by activation of pre-Bötzinger complex in vivo.

Journal: Journal of neurophysiology 20020301

Title: Evidence for postjunctional serotonin (5-HT1) receptors in the trigeminocervical complex.

Journal: Annals of neurology 20011201

Title: Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists.

Journal: Brain research 20010727

Title: The role of glutamate and vasopressin in the excitation of RVL neurones by paraventricular neurones.

Journal: Brain research 20010720

Title: Is the tricuspid position suitable for testing replacement bioprosthetic valves in the sheep model?

Journal: The Journal of heart valve disease 20010701

Title: Sympathetic nerve and cardiovascular responses to chemical activation of the midbrain defense region.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010601

Title: Influence of metabolic control on growth in homocystinuria due to cystathionine B-synthase deficiency.

Journal: Pediatric research 20010601

Title: Blockade of delta opioid receptors in the ventrolateral periaqueductal gray region inhibits the fall in arterial pressure evoked by hemorrhage.

Journal: The Journal of pharmacology and experimental therapeutics 20010501

Title: How protein kinase C activation protects nerve cells from oxidative stress-induced cell death.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010501

Title: The behavioural importance of dynamically activated descending inhibition from the nucleus reticularis gigantocellularis pars alpha.

Journal: Pain 20010501

Title: Sympathoinhibition from ventrolateral periaqueductal gray mediated by 5-HT(1A) receptors in the RVLM.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010401

Title: Sequence-selective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons.

Journal: Annals of neurology 20010301

Title: Involvement of GABA in medullary raphe-evoked modulation of neuronal activity in the periaqueductal grey matter in the rat.

Journal: Experimental brain research 20010301

Title: Periaqueductal grey mediated inhibition of responses to noxious stimulation is dynamically activated in a rat model of neuropathic pain.

Journal: Neuroscience letters 20010126

Title: Activation of the ventrolateral periaqueductal gray reduces locomotion but not mean arterial pressure in awake, freely moving rats.

Journal: Neuroscience 20010101

Title: [Adaptation of synaptic transmission to high concentrations of homocysteinic acid].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101

Title: Measurement of excitatory sulfur amino acids, cysteine sulfinic acid, cysteic acid, homocysteine sulfinic acid, and homocysteic acid in serum by stable isotope dilution gas chromatography-mass spectrometry and selected ion monitoring.

Journal: Analytical biochemistry 19940801

Title: Glycine antagonism by RU 5135.

Journal: European journal of pharmacology 19850416

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