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6950-84-1,MFCD00021444
Catalog No.:AA005L30

6950-84-1 | 1-(Naphthalen-1-yl)urea

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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA005L30
Chemical Name:
1-(Naphthalen-1-yl)urea
CAS Number:
6950-84-1
Molecular Formula:
C11H10N2O
Molecular Weight:
186.2099
MDL Number:
MFCD00021444
SMILES:
NC(=O)Nc1cccc2c1cccc2
NSC Number:
65627
UN Number:
1652
Properties
Properties
 
BP:
353.9°C at 760 mmHg  
Form:
Solid  
MP:
219.5℃  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
217  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
1.1  

Downstream Synthesis Route
6950-84-1    77-25-8   
5,5-diethyl-1-1naphthyl-barbituricacid 

[1]JournaloftheAmericanChemicalSociety,1936,vol.58,p.1284

6950-84-1    77-24-7   
5-ethyl-5-isopentyl-1-1naphthyl-barbituricacid 

[1]Buck[JournaloftheAmericanChemicalSociety,1936,vol.58,p.2059]

[1]Nasrollahzadeh,Mahmoud;Azarian,Abbas;Ehsani,Ali;Sajadi,S.Mohammad;Babaei,Ferydon[MaterialsResearchBulletin,2014,vol.55,p.168-175]

[1]Azarifar,Davood;Golbaghi,Maryam[JournalofSulfurChemistry,2016,vol.37,#1,p.1-13]

[1]CurrentPatentAssignee:NANJINGUNIVERSITYOFSCIENCEANDTECHNOLOGY-CN103664704,2016,BLocationinpatent:Paragraph0160-0163

Literature

Title: Structures, substrates, and regulators of Mammalian sirtuins - opportunities and challenges for drug development.

Journal: Frontiers in pharmacology 20120101

Title: The development of drugs for treatment of sleeping sickness: a historical review.

Journal: Parasites & vectors 20100101

Title: An electrochemical method for fluoride analysis based on a naphthalene urea derivative as a selective receptor.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080901

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Synthesis and biological evaluation of new symmetrical derivatives as cytotoxic agents and apoptosis inducers.

Journal: Bioorganic & medicinal chemistry 20050315

Title: Suramin has adjuvant properties and promotes expansion of antigen-specific Th1 and Th2 cells in vivo.

Journal: International immunopharmacology 20040101

Title: Ground-state conformational equilibrium and photochemical behavior of syn and anti N,N'-dimethyl-N,N'-di-1-naphthylurea protophanes.

Journal: Journal of the American Chemical Society 20031112

Title: A new fluoride selective fluorescent as well as chromogenic chemosensor containing a naphthalene urea derivative.

Journal: Journal of the American Chemical Society 20031015

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SDS
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