Home Pyridines 769-49-3
769-49-3,MFCD16883574
Catalog No.:AA00G4RJ

769-49-3 | 1-methyl-4-oxo-pyridine-3-carboxamide

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5mg
≥95%
in stock  
$155.00   $108.00
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10mg
≥95%
in stock  
$276.00   $193.00
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50mg
≥95%
in stock  
$1,068.00   $747.00
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100mg
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$1,829.00   $1,280.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00G4RJ
Chemical Name:
1-methyl-4-oxo-pyridine-3-carboxamide
CAS Number:
769-49-3
Molecular Formula:
C7H8N2O2
Molecular Weight:
152.1506
MDL Number:
MFCD16883574
SMILES:
Cn1ccc(=O)c(c1)C(=O)N
Properties
Computed Properties
 
Complexity:
266  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
-0.1  

Literature

Title: Simultaneous determination of nicotinic acid and its four metabolites in rat plasma using high performance liquid chromatography with tandem mass spectrometric detection (LC/MS/MS).

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100401

Title: Comparison of the nicotinamide catabolism among rat strains.

Journal: Bioscience, biotechnology, and biochemistry 20090201

Title: Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701

Title: 1-Methylnicotinamide and nicotinamide: two related anti-inflammatory agents that differentially affect the functions of activated macrophages.

Journal: Archivum immunologiae et therapiae experimentalis 20080401

Title: Nicotinamide metabolites accumulate in the tissues of uremic rats.

Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20080101

Title: Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.

Journal: International journal of clinical pharmacology and therapeutics 20070801

Title: Relationship between uremic toxins and oxidative stress in patients with chronic renal failure.

Journal: Scandinavian journal of urology and nephrology 20070101

Title: Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure.

Journal: Pediatric nephrology (Berlin, Germany) 20060601

Title: Comparison of metabolic fates of nicotinamide, NAD+ and NADH administered orally and intraperitoneally; characterization of oral NADH.

Journal: Journal of nutritional science and vitaminology 20060401

Title: Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060201

Title: Final report of the safety assessment of niacinamide and niacin.

Journal: International journal of toxicology 20050101

Title: Conversion ratio of tryptophan to niacin in Japanese women fed a purified diet conforming to the Japanese Dietary Reference Intakes.

Journal: Journal of nutritional science and vitaminology 20041201

Title: Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography.

Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101

Title: Increase in conversion of tryptophan to niacin in pregnant rats.

Journal: Advances in experimental medicine and biology 20030101

Title: Identification of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-5-carboxamide as components in urine extracts of individuals consuming coffee.

Journal: Journal of pharmaceutical and biomedical analysis 20021015

Title: Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.

Journal: Bioscience, biotechnology, and biochemistry 20020601

Title: Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.

Journal: Bioscience, biotechnology, and biochemistry 20010601

Title: [Effect of feeding with a poisonous mushroom Clitocybe acromelalga on the metabolism of tryptophan-niacin in rats].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010601

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