Title: Translesion polymerase η is upregulated by cancer therapeutics and confers anticancer drug resistance.
Journal: Cancer research 20141001
Title: The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140701
Title: Can ex vivo evaluation (testing) predict the sensitivity of CLL cells to therapy with purine analogs in conjunction with an alkylating agent? A comparison of in vivo and ex vivo responses to treatment.
Journal: Medical oncology (Northwood, London, England) 20120901
Title: Pilot study of systemic and intrathecal mafosfamide followed by conformal radiation for infants with intracranial central nervous system tumors: a pediatric brain tumor consortium study (PBTC-001).
Journal: Journal of neuro-oncology 20120901
Title: Mafosfamide as a new anticancer agent: preclinical investigations and clinical trials.
Journal: Anticancer research 20120701
Title: TRAIL and taurolidine enhance the anticancer activity of doxorubicin, trabectedin and mafosfamide in HT1080 human fibrosarcoma cells.
Journal: Anticancer research 20120701
Title: Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases.
Journal: The Journal of biological chemistry 20111216
Title: Zoledronic acid as a new adjuvant therapeutic strategy for Ewing's sarcoma patients.
Journal: Cancer research 20101001
Title: Roscovitine triggers apoptosis in B-cell chronic lymphocytic leukemia cells with similar efficiency as combinations of conventional purine analogs with cyclophosphamide.
Journal: Annals of the New York Academy of Sciences 20090801
Title: Calorimetric study as a potential test for choosing treatment of B-cell chronic lymphocytic leukemia.
Journal: Leukemia research 20090201
Title: Low-dose metronomic cyclophosphamide treatment mediates ischemia-dependent K-ras mutation in colorectal carcinoma xenografts.
Journal: Oncogene 20080612
Title: Apoptotic death induced by the cyclophosphamide analogue mafosfamide in human lymphoblastoid cells: contribution of DNA replication, transcription inhibition and Chk/p53 signaling.
Journal: Toxicology and applied pharmacology 20080515
Title: Synergy of karenitecin and mafosfamide in pediatric leukemia, medulloblastoma, and neuroblastoma cell lines.
Journal: Pediatric blood & cancer 20080401
Title: In vitro sensitivity of B-cell chronic lymphocytic leukemia to cladribine and its combinations with mafosfamide and/or mitoxantrone.
Journal: Oncology reports 20061201
Title: Xrcc2 deficiency sensitizes cells to apoptosis by MNNG and the alkylating anticancer drugs temozolomide, fotemustine and mafosfamide.
Journal: Cancer letters 20060808
Title: A novel triple purge strategy for eliminating chronic myelogenous leukemia (CML) cells from autografts.
Journal: Bone marrow transplantation 20060301
Title: New agents for intrathecal administration.
Journal: Cancer investigation 20060101
Title: Ex vivo expansion of mafosfamide-purged PBPC products.
Journal: Cytotherapy 20060101
Title: Mafosfamide: a new intra-CSF chemotherapy?
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051020
Title: Intrathecal mafosfamide: a preclinical pharmacology and phase I trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050301
Title: Bone marrow-resident memory T cells survive pretransplant chemotherapy and contribute to early immune reconstitution of patients with acute myeloid leukemia given mafosfamide-purged autologous bone marrow transplantation.
Journal: Experimental hematology 20050201
Title: Phase I clinical trial of mafosfamide in infants and children aged 3 years or younger with newly diagnosed embryonal tumors: a pediatric brain tumor consortium study (PBTC-001).
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050120
Title: In B-CLL, the codon 72 polymorphic variants of p53 are not related to drug resistance and disease prognosis.
Journal: BMC cancer 20050101
Title: Activation of mitochondrial apoptotic pathway in mantle cell lymphoma: high sensitivity to mitoxantrone in cases with functional DNA-damage response genes.
Journal: Oncogene 20041125
Title: Is the combination with 2-methoxyestradiol able to reduce the dosages of chemotherapeutices in the treatment of human ovarian cancer? Preliminary in vitro investigations.
Journal: European journal of gynaecological oncology 20040101
Title: Feasibility of long-term intraventricular therapy with mafosfamide (n = 26) and etoposide (n = 11): experience in 26 children with disseminated malignant brain tumors.
Journal: Journal of neuro-oncology 20030901
Title: Successful chemotherapy in a male patient with malignant lymphoma and Leber's hereditary optic neuropathy (LHON).
Journal: American journal of hematology 20030401
Title: Response of hematopoiesis to cyclophosphamide follows highly specific patterns in bone marrow and spleen.
Journal: Journal of hematotherapy & stem cell research 20030201
Title: Long-term outcome in acute myelogenous leukemia autografted with mafosfamide-purged marrow in a single institution: adverse events and incidence of secondary myelodysplasia.
Journal: Bone marrow transplantation 20020701
Title: Hyperthermia and mafosfamide in a human-derived malignant pleural mesothelioma cell line.
Journal: Journal of cancer research and clinical oncology 20020201
Title: Induction of apoptosis by cladribine (2-CdA), gemcitabine and other chemotherapeutic drugs on CD34+/CD38+ and CD34+/CD38- hematopoietic progenitor cells: selective effects of doxorubicin and 2-CdA with protection of immature cells.
Journal: Leukemia & lymphoma 20020201
Title: In vitro activity of glufosfamide in childhood acute leukemia.
Journal: Anticancer research 20020101
Title: Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells.
Journal: Molecular pharmacology 20011201
Title: Ex vivo expansion of normal progenitor cells from acute myeloid leukemia cell-contaminated CD34+ peripheral blood progenitor cells after mafosfamide purging.
Journal: Journal of hematotherapy & stem cell research 20011201
Title: High-dose melphalan with autologous hematopoietic stem cell transplantation for acute myeloid leukemia: results of a retrospective analysis of the Italian Pediatric Group for Bone Marrow Transplantation.
Journal: Bone marrow transplantation 20010701
Title: Protection of mammalian cells against chemotherapeutic agents thiotepa, 1,3-N,N'-bis(2-chloroethyl)-N-nitrosourea, and mafosfamide using the DNA base excision repair genes Fpg and alpha-hOgg1: implications for protective gene therapy applications.
Journal: The Journal of pharmacology and experimental therapeutics 20010301
Title: Overview of the treatment of infant central nervous system tumors: medulloblastoma as a model.
Journal: Journal of pediatric hematology/oncology 20010101
Title: De novo expression of transfected human class 1 aldehyde dehydrogenase (ALDH) causes resistance to oxazaphosphorine anti-cancer alkylating agents in hamster V79 cell lines. Elevated class 1 ALDH activity is closely correlated with reduction in DNA interstrand cross-linking and lethality.
Journal: The Journal of biological chemistry 19960517
Title: Oxazaphosphorine cytostatics: past-present-future. Seventh Cain Memorial Award lecture.
Journal: Cancer research 19890101
Title: Cause and prevention of mafosfamide-induced venous pain.
Journal: Investigational new drugs 19860101
Title: Phase I study of cyclohexylamine and lysine salt of mafosfamide.
Journal: Cancer chemotherapy and pharmacology 19860101
