Title: Effect of decursin on the pharmacokinetics of theophylline and its metabolites in rats.
Journal: Journal of ethnopharmacology 20121121
Title: Effect of decursinol angelate on the pharmacokinetics of theophylline and its metabolites in rats.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001
Title: Development and validation of a sensitive LC-MS/MS method for the simultaneous quantitation of theophylline and its metabolites in rat plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120315
Title: Metabolite profiling of Angelica gigas from different geographical origins using 1H NMR and UPLC-MS analyses.
Journal: Journal of agricultural and food chemistry 20110824
Title: Development and validation of a LC-MS/MS method based on a new 96-well Hybrid-SPE™-precipitation technique for quantification of CYP450 substrates/metabolites in rat plasma.
Journal: Analytical and bioanalytical chemistry 20110601
Title: Usefulness of the simultaneous determination of serum levels of theophylline and its metabolites in patients medicated with theophylline preparation.
Journal: Biomedical chromatography : BMC 20110401
Title: Nanosized rods agglomerates as a new approach for formulation of a dry powder inhaler.
Journal: International journal of nanomedicine 20110101
Title: Nitrosation of N-methyl derivatives of uric acid and their transnitrosation ability to N-acetylcysteine.
Journal: Chemical & pharmaceutical bulletin 20100901
Title: Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Journal: Bioorganic & medicinal chemistry letters 20100101
Title: A synthetic uric acid analog accelerates cutaneous wound healing in mice.
Journal: PloS one 20100101
Title: Demethylation of theophylline (1,3-dimethylxanthine) to 1-methylxanthine: the first step of an antioxidising cascade.
Journal: Redox report : communications in free radical research 20100101
Title: Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
Journal: Journal of bacteriology 20090701
Title: Relaxing and contracting effects of theophylline's metabolites on the rabbit upper gastrointestinal tract.
Journal: Fundamental & clinical pharmacology 20081001
Title: Time-dependent effects of Klebsiella pneumoniae endotoxin (KPLPS) on the pharmacokinetics of theophylline in rats: return of the parameters in 96-hour KPLPS rats to the control levels.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080501
Title: [Population pharmacokinetic analysis of two theophylline formulations in premature neonates and infants with apnea].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080401
Title: Anti-inflammatory effect of theophylline in rats and its involvement of the glucocorticoid-glucocorticoid receptor system.
Journal: Journal of pharmacological sciences 20080401
Title: Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU.
Journal: The Journal of pharmacy and pharmacology 20080101
Title: Theophylline and its metabolites produce a stimulating cholinergic effect on the small intestine and a nonadrenergic noncholinergic relaxing effect on the colon: a comparative study in the rabbit intestine.
Journal: Journal of veterinary pharmacology and therapeutics 20071201
Title: Effects of water deprivation on the pharmacokinetics of theophylline and one of its metabolites, 1,3-dimethyluric acid, after intravenous and oral administration of aminophylline to rats.
Journal: Biopharmaceutics & drug disposition 20071101
Title: 7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.
Journal: Bioorganic & medicinal chemistry 20070801
Title: Lack of effect of aciclovir on metabolism of theophylline and expression of hepatic cytochrome P450 1A2 in rats.
Journal: Biological & pharmaceutical bulletin 20070301
Title: Associations between CYP2E1 promoter polymorphisms and plasma 1,3-dimethyluric acid/theophylline ratios.
Journal: European journal of clinical pharmacology 20060801
Title: Effect of a newly developed ketolide antibiotic, telithromycin, on metabolism of theophylline and expression of cytochrome P450 in rats.
Journal: Life sciences 20060530
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Liver dysfunction markedly decreases the inhibition of cytochrome P450 1A2-mediated theophylline metabolism by fluvoxamine.
Journal: Clinical pharmacology and therapeutics 20060501
Title: Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1,3-dimethyluric acid formation.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050901
Title: Methylated purines in urinary stones.
Journal: Clinical chemistry 20050801
Title: Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice.
Journal: Pharmacogenetics and genomics 20050701
Title: Inhibition of theophylline metabolism by suplatast and its metabolites in rats.
Journal: Biological & pharmaceutical bulletin 20050601
Title: Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m).
Journal: European journal of clinical pharmacology 20050301
Title: Uric acid may inhibit glucose-induced insulin secretion via binding to an essential arginine residue in rat pancreatic beta-cells.
Journal: Bioorganic & medicinal chemistry letters 20050215
Title: High-throughput liquid chromatography-tandem mass spectrometry assay for plasma theophylline and its metabolites.
Journal: Clinical chemistry 20041101
Title: Separation, pre-concentration, and HPLC analysis of methylxanthines in urine samples.
Journal: Journal of separation science 20041001
Title: Catabolism of caffeine in plants and microorganisms.
Journal: Frontiers in bioscience : a journal and virtual library 20040501
Title: Pharmacokinetics of intravenous theophylline in mutant Nagase analbuminemic rats.
Journal: Life sciences 20030131
Title: Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1,3-dimethyluric acid formation.
Journal: The Journal of pharmacy and pharmacology 20021201
Title: Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange.
Journal: Journal of medicinal chemistry 20011220
Title: Effect of alosetron on theophylline pharmacokinetics.
Journal: British journal of clinical pharmacology 20011101
Title: Use of novel solid-phase extraction sorbent materials for high-performance liquid chromatography quantitation of caffeine metabolism products methylxanthines and methyluric acids in samples of biological origin.
Journal: Journal of chromatography. B, Biomedical sciences and applications 20010815
Title: Caffeine metabolism before and after liver transplantation.
Journal: International journal of clinical pharmacology and therapeutics 20010201
Title: Caffeine metabolism in a group of 67 patients with primary biliary cirrhosis.
Journal: International journal of clinical pharmacology and therapeutics 20010101
Title: Dose dependent pharmacokinetics of theophylline: Michaelis-Menten parameters for its major metabolic pathways.
Journal: European journal of drug metabolism and pharmacokinetics 20010101
Title: Neurotoxic convulsions induced by theophylline and its metabolites in mice.
Journal: Biological & pharmaceutical bulletin 19960601
Title: Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii.
Journal: Biochemical pharmacology 19951109
Title: Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats.
Journal: The Journal of pharmacology and experimental therapeutics 19860301
